The F2-isoprostane approach allows for analysis of FOXO transcription factor control of endogenous oxidative stress. by Christiaan F. Labuschagne (485155)

“…DLD-1 and DL-23 cells were incubated with 4-OHT to activate FOXO3a for 24 hours, before treatment with PQ for another 8 hours. 5-iPF2α-VI levels were analyzed and data are represented as mean fold increase ± S.E.M (*p < 0.05, *** p < 0.001).…”

Corneal nerve damage in primary acute herpes simplex keratitis is due to viral proliferation and not corneal inflammation. by Kai Hu (311882)

“…<p><b>A, B:</b> Corneal nerve density was significantly decreased in PSGL1-KO mice as compared to WT mice after HSV-1 infection (n = 5/time point). …”

Neutralization of plasmas against spike-pseudotyped lentiviral particles. by Allison J. Greaney (11046384)

“…Right: summary plot of the geometric mean across cohorts of the fold-decrease in neutralization compared to Delta spike (left axis) or D614G spike (right axis). …”

DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx by Chen Zhou (466781)

“…A decrease of plasma glucose and increase of insulin and C-peptide were observed following OGTT in cetagliptin groups. …”

TGF-β1-induced suppression of COX-2 expression by transcriptional repression. by Erina Takai (465811)

“…<p>(A) Time-dependent decrease of COX-2 mRNA expression by treatment with TGF-β1 (5 ng/mL). …”

Dose response experiments. by Piotr Ruchala (197975)

Expression Modulation of Genes with Promoters Hyper- and Hypo-acetylated at H3K9. by Takahiro Suzuki (88656)

Chronic CSE treatment induced HIF1α accumulation via enhanced lactate production. by Wenyue Sun (134001)

“…HIF1α levels in OKF6 cells were determined after 4 h of culture in glucose-free Krebs buffer containing 3 or 5 mmol/L lactate. Treatment with 3 and 5 mmol/L lactate caused HIF1α accumulation by 1.3±0.1-fold and 1.9±0.2-fold, respectively. …”

Kinetics of differential gene expression after rapid degradation of endogenous OGT in MEFs. by Sara Formichetti (20536052)

“…Differentially expressed genes with p-value < 10⁻⁵ and absolute log₂FC > 0.3 (i.e. 1.2-fold increase or decrease in expression) are colored in red and their number is indicated. …”

Gene expression profiling of Ch cells. by Sebastián Cachero (233711)

“…GFP fluorescence is also detected in several <i>ato</i>-dependent head sense organs, including Bolwig's Organ (BO), Dorsal Organ (DO), and Ventral Organ (VO). (E) Venn diagram of genes enriched in <i>ato</i>GFP cells at three developmental time points, representing the first 3 h of Ch cell development. …”

Warfarin pretreatment enhances tumor Ad5ROBO4 vector expression. by Zhi Hong Lu (389413)

Clinical findings in SHIV-infected rhesus monkeys challenged with ZEBOV. by Thomas W. Geisbert (328805)

Cardiovascular and respiratory effects of lumbosacral epidural bupivacaine in isoflurane-anesthetized dogs: The effects of two volumes of 0.25% solution by Raquel Sartori Gonçalves Dias (5117654)

“…Comparisons between and within groups were performed by a mixed-model ANOVA and Friedman’s test when appropriate followed by Bonferroni post-hoc test or Dunnet’s test to compare time points within each treatment with T0 (<i>p</i> < 0.05). Mean arterial pressure decreased significantly from 15 to 90 minutes after the administration of BUP02 and from 5 to 60 minutes in BUP04, with lower values in BUP04 than in BUP02 lasting up to 30 minutes after bupivacaine administration. …”

WV phase space projection for QIF model with spike waveform, and convergent iterative theoretical predictions for <i>μ</i> > <i>μ</i>* and <i>μ</i> → 0. by Adam D. Schneider (148548)

“…Inset shows the cyan trajectory in terms of decaying variables <i>x</i>*(<i>t</i>) and <i>C</i>*(<i>t</i>), and how <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159300#pone.0159300.e084" target="_blank">Eq (22)</a> captures the initial increase and then decrease in the calcium concentration, while <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159300#pone.0159300.e083" target="_blank">Eq (21)</a> does not. …”

Adseverin expression is up-regulated during OCG in response to sRANKL. by Siavash Hassanpour (638306)

“…In BMM-derived osteoclasts, Ads expression was significantly up-regulated by 10-fold after 2 days and 23-fold after 4 days. No difference was noted between Day 4 and Day 6 cultures. …”

Critical period EB odorant experience via Or42a neurons specifically elevates VM7 serotonin signaling. by Vanessa Kay Miller (19775496)

“…Individual data points with mean ± SEM. Significance indicated as <i>p</i> < 0.0001 (****). …”

endoR captures interactions predictive of an artificial phenotype from a random forest fitted on real metagenomes. by Albane Ruaud (14259687)

“…If high values are predictive of ‘1’ or ‘-1’ depending of other variable values (e.g., Group b predicts ‘1’ if V3 takes high values, but ‘-1’ if V3 has low values), the color is grey (‘depends’). …”

FIGURE 4 from HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity by Priyanka S. Rana (15136410)

“…<b>E,</b> Shown is the peptide sequence, fold decrease, and gene accession for the 20 peptides most downregulated by bortezomib treatment. …”

Developmentally regulated promoter-switch transcriptionally controls function during embryonic hematopoiesis-5 by Amir Pozner (78042)

“…Note the 4-fold decrease in the proportions of c-Kit/B220/D19TCPs (R2) in P2FL HPC. …”

TGFβ signaling promotes NDR1 turnover. by Isabelle Pot (427025)

“…Data are presented as the mean+SEM (n = 4) of percent decrease in protein abundance of NDR1 in NMuMG cells in response to TGFβ. …”