The power for detecting association with secondary traits in selected samples. by Dajiang J. Liu (120143)

“….), where 80% of the causal variants increase the mean secondary trait value and the other 20% decrease the mean secondary trait value. …”

Analysis of TCGA data reveals SRRM4 silencing in cancer across tissue types. by Sarah A. Head (6066398)

“…(D) The sum of the number of tissues with significantly up-regulated (positive) and down-regulated (negative) expression in tumors, for each of the 202 SFs. (E) Fold change in median expression of the 4 SFs that consistently increase across all tumor types (blue) and SRRM4, which decreases in tumors (red), with each point representing 1 tissue. …”

Proteasome inhibition decouples infectious DENV2 production from viral RNA replication in THP-1 cells. by Milly M. Choy (790882)

“…(D) Proteasome inhibition showed a dose-dependent decrease in plaque titers 48 hpi. Mean ± SD. N = 4. …”

Introduction of FOXA1 into AB32 cells alters progestin response. by Christine L. Clarke (169388)

“…Red - increased log fold expression, green - decreased log fold expression. …”

Alanine-scanning mutagenesis of EnvZ. by Emily J. Capra (236597)

“…For panels C and E, the mutant kinases were autophosphorylated for 60 minutes prior to assessing phosphotransfer. …”

Bioenergetics of wildtype and <i>ATP6¹</i> animals. by Alicia M. Celotto (203614)

“…Error is S.E.M. Statistical analysis is student's t-test. …”

CgHog1 negatively regulates CgSub2-CgHtz1 interaction. by Mahima Sagar Sahu (18555062)

“…The arrow denotes CgSub2 protein band (65 kDa). Fold-decrease in CgSub2-CgHtz1 interaction (mean ± SEM; n = 3) in ferric chloride-grown <i>wt</i>, compared to YNB-grown <i>wt</i> cells (taken as 1.0), is shown underneath the blot. *, p ≤ 0.05, paired two-tailed Student’s <i>t</i> test. …”

Temporal Trends in Exposures to Six Phthalates from Biomonitoring Data: Implications for Cumulative Risk by Jeanette M. Reyes (1306353)

“…Over this period, there was a 2.2-fold decrease in the mean HI (0.34 to 0.15) and a 7.2-fold decrease in the percentage of participants with an HI > 1 (5.7% to 0.8%), indicating an overall decrease in combined exposure to these phthalates. …”

SREBP-1 is dispensable but not required for neuritogenic effect of SIM. by Varshiesh Raina (457377)

“…SIM led no change on SREBP-1 cleavage except that a significant (<i>p</i> < 0.05^*) decrease was observed at 2 hrs. Error bar graph represents the fold change (normalized to actin) in p68 protein form at different time points in presence of SIM (mean ± SEM; n = 3). …”

Mast cell density and ano-genital sensitivity following therapeutic imatinib treatment in ND4 female mice previously exposed to MI. by Jaclyn M. Kline (9565161)

“…(C) Quantification of avidin⁺ mast cell density in 10 μm labiar skin cryo-sections collected 1 day after 6 daily therapeutic Imatinib treatments or NT following 10 daily MI treatments in previously sensitized mice. Results displayed as mean ± SEM, n = 5-6/treatment group, representing 2 experiments. …”

Heatmaps of drug-induced gene expression (GE), performed two years apart. by Stacy L. Sell (7305545)

“…Genes > 1.5 fold in the same direction in at least five drug treatments vs TBI and <i>p</i>-value < .05 in at least one drug treatment vs. …”

Lack of Integration into Dentate Gyrus Memory Circuits of New Neurons Derived from Dentate Gyrus Progenitor Cells Whose Differentiation Was Anticipated by Stefano Farioli-Vecchioli (256006)

“…</p> <p>(D) New neurons were generated with equivalent frequency in the Tg<i>PC3</i> ON and Tg<i>PC3</i> OFF groups, as indicated by the similar percentage ratio between number of new neurons (BrdU⁺/NeuN⁺) and total number of neurons (NeuN⁺ cells) identified 2, 4, and 6 wk after BrdU treatment (<i>F</i>(5, 122) = 0.24; <i>p</i> > 0.05, ANOVA).</p> <p>(E) After behavioral training, the presence of activated neurons in the whole neuronal population of the dentate gyrus—measured as percentage ratio of c-fos⁺/NeuN⁺ to NeuN⁺ cells—was similar in all groups of Tg<i>PC3</i> OFF mice, whereas in Tg<i>PC3</i> ON mice the presence of activated neurons was significantly reduced in the 4- and 6-wk groups, indicating a progressive decrease in the population of active neurons (<i>F</i>(5, 112) = 16.0; <i>p</i> < 0.0001, ANOVA. …”

Cardiovascular genes are dysregulated in FVB/N KLF2−/− AV region. by Aditi R. Chiplunkar (282141)

“…FVB/N WT and mix WT were designated as100%, and KLF2−/− were compared to WT. (<b>A–C</b>) In E10.5 FVB/N KLF2−/− AV region there is significantly decreased expression of (<b>A</b>) Tbx5 (p = 0.0175), (<b>B</b>) Gata4 (p = 0.0164) and (<b>C</b>) Sox9 (p = 0.019) mRNA compared to FVB/N WT, but Mix WT and Mix KLF2−/− hearts have no differences in expression of these genes. …”

RNA-seq transcriptomics analysis in human tissue culture cells reveals changes in the expression levels of over 100 nucleolar mRNAs after PAX9 knockdown. by Katherine I. Farley-Barnes (9258036)

“…Of the 184 mRNAs whose levels were decreased and that also code for nucleolar proteins, 5 were chosen as candidates for follow-up studies. …”

Remodeling of Purkinje dendrites in the third postnatal week. by Megumi Kaneko (219519)

“…<b>D</b>: Overpassing branches per cell peak at P18, sharply decrease by P22 and plateau thereafter. <b>E</b>: The mean length of each dendritic branch decreases between P7 and P9, constantly increases until P35 and then slightly decreased by P50. …”

Rapamycin improved CA1 dendritic arborization and spine density in hippocampi from rats subjected to SE. by Amy L. Brewster (388121)

“…(<b>A</b>) Representative images of golgi-stained CA1 neurons and their respective reconstructions showing the branch points from the apical dendrites. (<b>B</b>) Branch point analysis normalized to percent of Sham+Veh (% control) shows a significant decrease in the apical dendrite branch points in the SE+Veh compared to the Sham+Veh group that is reversed in the SE+Rap group; n = 4−6 brains/group from which 4–17 cells/brain were analyzed. …”

<i>phox2b</i>, but not <i>ascl1</i>, is indispensable for sympathetic neuronal differentiation. by Desheng Pei (418653)

“…Lateral views depict a minimal decrease in expression of <i>th</i> (A,B) and <i>dbh</i> (D,E) in <i>ascl1</i> MO-injected embryos compared to control MO-injected (A,D) embryos. …”

Comparison of Bursting Activity in Real and Modelled Oxytocin Cells. by Enrico Rossoni (271791)

“…<p>(A) A typical burst in a model cell plotted as instantaneous firing rate (each point is the reciprocal of the interval since the previous spike). …”

Quantitative determination of loss of MMP in Neuro-2a cells in response to Grx1 knockdown. by Uzma Saeed (49670)

“…Loss of MMP due to the Grx1 knockdown is maintained by pretreating the cells with α-lipoic acid and cyclosporine A (E). Arrow represents time point of addition of CCCP.…”

Siglec-1 expressed in LPS mDCs capture distinct ganglioside containing vesicles, such as HIV-1 viral-like particles, liposomes, and exosomes. by Nuria Izquierdo-Useros (91232)

“…Of note, Siglec-14 shares 100% of amino acid homology with Siglec-5 in the V-set domain. Data show mean values and SEMs from three experiments including cells from nine donors. …”