Poly (I∶C) induces BACE1 translation in a mechanism depending on PKR-catalysed eIF2-alpha phosphorylation. by Gerard ILL-Raga (349258)

“…<p>BACE1 5′UTR fragment was inserted into the HindIII site of a luciferase reporter construct (5′UTR-luc). …”

Properties of the voltage-gated sodium current from honeybee ALNs. by Aklesso Kadala (659345)

“…<p>A, Sodium current traces obtained from an ALN for voltage steps to the indicated potential from a holding potential of −80 mV. B, Mean relative I/V curve (n = 24). C, Mean steady-state inactivation curve (n = 12). …”

Several VDAs induce abnormal vacuolar morphologies. by Helene Tournu (3713263)

Data_Sheet_1_Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers.XLSX by Helen He (345966)

“…Tape-strips from lesional and non-lesional skin were collected before and after treatment, and analyzed with the Olink proteomic assay. Using criteria of fold-change>1.5 and FDR < 0.05, 136 proteins significantly decreased after dupilumab treatment, corresponding to an overall mean improvement of 66.2% in the lesional vs. non-lesional AD proteome. …”

Supplementary Material for: Predictive Value of Thrombus Attenuation on Thin-Slice Non-Contrast CT for Persistent Occlusion after Intravenous Thrombolysis by Niesten J.M. (3231759)

“…Odds ratios for persistent occlusion were 3.1 (95% confidence interval, CI 1.6-6.0) univariate and 3.1 (95% CI 1.7-5.7) multivariate per 10 absolute HU decrease and 3.2 (95% CI 1.6-6.5) univariate and 4.1 (95% CI 1.8-9.1) multivariate per 0.20 relative HU decrease. …”

Data_Sheet_1_Coastal Flooding in the Balearic Islands During the Twenty-First Century Caused by Sea-Level Rise and Extreme Events.zip by Pau Luque (11248140)

“…According to our calculations, permanent flooding by the end of our century will extend 7.8–27.7 km² under the RCP4.5 scenario (mean sea-level rise between 32 and 80 cm by 2100), and up to 10.9–36.5 km² under RCP8.5 (mean sea-level rise between 46 and 103 cm by 2100). …”

Time course of changes in global background synaptic conductances during perfusion with bicuculline. by Stuart David Greenhill (509476)

“…The combine effect was a sustained decrease in I∶E ration that reversed in favour of excitation around the time when paroxysmal activity appeared. …”

Datasheet1_Trends in hypertension and hypertension treatment in primary care in general practices in Germany between 2013 and 2022.pdf by Karel Kostev (2577346)

“…The mean (SD) age of patients per practice was between 48.4 (21.5) and 50.5 (21.4) years, while the proportion of women was 52.1%–53.9% (p-values < 0.001). …”

Peroxide-induced perturbations to lipid metabolism in trophozoite-stage parasite cultures. by Carlo Giannangelo (8053910)

Effect of sagopilone (SAG) on cell proliferation, tubulin cytoskeleton, cell cycle and apoptosis of lung cancer cells. by Sebastian Winsel (222664)

“…Proliferation was measured with crystal violet assay. Mean IC50 values as measure of the half-maximal growth inhibition and standard deviations are shown. 1B, Immunofluorescence staining of α-tubulin (green) and DNA (red) in A549 lung cancer cells after incubation with either vehicle (0.1% ethanol), 2.5 nM, or 40 nM SAG. …”

Data Sheet 1_Monitoring career impact and satisfaction in a graduate program in dentistry.docx by Isadora dos Santos Rotta (21195653)

“…</p>Methods<p>The employed instrument comprised a total of 43 questions presenting a mix of both close and open-ended questions coupled with 5-point Likert scales. The questionnaire was hosted online and a total of 528 alumni were invited to participate through e-mail and social media outreach.…”

Determining tumor cell content in cultured malignant effusions. by Christian Ruiz (117039)

“…Example of the tumor cell decrease in a malignant effusion from a patient with lung adenocarcinoma. …”

Extended differentiation in presence of tumor cell-conditioned media preserves RANKL and PTHrP expression but promotes osteoblast apoptosis. by Shamik Das (174657)

“…At the end of each time point RNA was harvested from the differentiated osteoblastic cells and levels of BSP, osteocalcin, PTHrP and RANKL were assessed by qRT-PCR. …”

Discordant effect of rs7422195 in the presence or absence of <i>HLA-DRB1*15</i>:<i>01</i>. by Michele D. Binder (230662)

CERT function is required for <i>C. trachomatis</i> replication. by Cherilyn A. Elwell (43466)

“…CERT depletion reduced inclusion size. Red arrows point to inclusions. Scale bar = 5 µm. (G) HeLa cells were depleted of CERT for 3 days, infected with <i>C. trachomatis</i> L2 and analyzed for inclusion size and progeny formation. …”

% viability of migrated cells at 24, 48 and 72h. by Meghana Kanitkar (438168)

“…Results are represented as mean ± SD of at least 3 independent experiments (n = 4/5).…”

Training and Test Set Classification Accuracy for Naïve Bayes Method Using Motif Scores Only by Yuan Yuan (25702)

“…Including too many features will overfit the training set and thus decrease the test set accuracies. 100 random repeats of 5-fold CVs were performed, and the curves display the mean accuracies. …”

Effect of TAK-242 on LPS-induced inhibition of myogenesis. by Yuko Ono (1443175)

“…Data are the mean ± SEM of 10 independent experiments per treatment group, each examining 5 randomly selected fields (total 50 fields). …”

EP DBS does not correct forelimb asymmetry or provide neuroprotection from 6-OHDA. by D. Luke Fischer (777040)

“…<p><b>(A)</b> Rats receiving intrastriatal 6-OHDA followed by either ACTIVE or INACTIVE EP DBS were analyzed for forelimb use asymmetry in the cylinder. 6-OHDA led to a significant decrease in contralateral forelimb use. However, ACTIVE EP DBS showed no difference compared to INACTIVE DBS at any time point. …”

One Realization of System Development for 400 Infections on a 70 × 70 Lattice by Sean P Stromberg (379540)

“…For most of the simulation, expected loss <i>J, </i><a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020160#pcbi-0020160-e018" target="_blank">Equation 18</a>, tends to decrease, yet rare events are increasing in size resulting in increased variance <i>σ, </i><a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020160#pcbi-0020160-e019" target="_blank">Equation 19</a>. …”