Acute and chronic effects of LPS on left ventricular (LV) size and function by echocardiography. by Wilbur Y. W. Lew (400836)

“…<p>Panel A: LV fractional shortening and heart rate (beats per minute, bpm) measured before (0 hours), and 6 and 24 hours after i.p. injection of saline (control), LPS 1, 10, or 20 mg/kg (each bar, mean+SEM, n = 6). There was a mild decrease in LV fractional shortening after 6 hours with LPS 10 and 20 mg/kg (*P<0.05 vs LPS 1 mg/kg or control) that resolved by 24 hours. …”

Data_Sheet_1_Light-Induced Dynamic Change of Phytochrome B and Cryptochrome 1 Stabilizes SINATs in Arabidopsis.docx by Jin Hu (187088)

“…We previously identified a class of SINA RING-type E3 ligases of Arabidopsis thaliana (SINATs), whose protein levels decrease in the dark and increase in red and blue light, but the underlying mechanism is unclear. …”

X-ray solution scattering analysis indicating that fragmentation is radiation dose dependent. by Timothy R. Stachowski (9652625)

“…A Dimensionless Kratky plot (e) also indicates that the protein is changing shape during irradiation.…”

The structure of spontaneous locomotion in zebrafish larvae and mice during the active phase of the circadian cycle (light for zebrafish larvae, dark for mice). by Stefan Spulber (148803)

“…B, C, E, F – one-way ANOVA followed by Dunnett's post-hoc test; * p<0.05 PFOS exposed vs. control. …”

Identification of a Novel Variant <i>c.163delG</i> in <i>HBB</i> Gene Resulting in a Beta Null Phenotype in a Proband with Thalassemia Intermedia by M. Mamata (17831752)

“…FoldX protein stability analysis showed a positive ΔΔG value of 45.27 kcal/mol suggesting a decrease in protein stability. …”

TXNIP loss expands the Myc transcriptome. by Tian-Yeh Lim (14808976)

Force-frequency relationship in zebrafish ventricular myocardium. by Moritz Haustein (734263)

“…(D) Maximal contraction velocity normalised to amplitude (dF/d<i>t</i>_max) was increased at higher stimulation rates, while maximal relaxation velocity normalised to amplitude (dF/d<i>t</i>_min) was unchanged. (E) Time to point of maximal contraction velocity (dF/d<i>t</i>_max) and time to peak (TTP) decreases at higher stimulation rates indicating an acceleration of contraction. …”

Acute hyperphagia in <i>pmch</i>^−/− rats when newly presented with HF diet. by Joram D. Mul (221970)

“…Acute hypophagia was equal between genotypes (14±8% decrease in <i>pmch</i>^+/+ rats as compared to 17±7% decrease in <i>pmch</i>^−/− rats; *<i>P</i><0.05 versus HF days1–5, repeated-measures ANOVA with special contrast analysis; n = 6–8 per group). …”

AMD3100 is PC-specific, altering PC migration towards SDF1α, but not towards PDGF-BB. by Robert J. Allen Jr. (540312)

“…<b>B</b>) Additionally, AMD3100 treatment of either cell line did not alter adhesion to fibronectin-coated chamber slides. <b>C</b>) After 5×10⁴ diabetic PCs were seeded on a fibronectin-coated 24-transwell insert with a receiver compartment containing media supplemented with either SDF1α (100 mg/ml) or PDGF-BB (100 ng/ml) and allowed to migrate for 20 hours, we found that AMD3100 treatment significantly impaired PC migration towards SDF1α (25% decrease, p<0.05) but not towards PDGF-BB (8.4% decrease, p>0.05). …”

TgNFS2 depletion impacts apicoplast-related pathways and has deleterious effects on parasite replication. by Sarah Pamukcu (11726372)

“…Scale bar represents 5 μm. DNA was labelled with DAPI. DIC: differential interference contrast.…”

NIH3T3 cells expressing Cx43dT-GFP show defects in wound closure and polarized cell movement. by Richard Francis (201117)

“…Quantitative assessment showed a significant decrease in wound closure rate in the Cx43dT-GFP expressing NIH3T3 cells at 4 and 5 hrs after wounding (G) (p<0.05). …”

Anterior segment optical coherence tomography in acute anterior uveitis by Cristiana Agra (5766521)

“…There was no significant change in temporal AC angle between visits, 44.3 ± 14.4 degrees before treatment and 44.7 ± 14.7 degrees fifteen days after (p=0.9343), and mean intraocular pressure, 10.8 ± 4.5 mmHg before treatment and 12.3 ± 3.0 mmHg fifteen days after (p=0.1874). …”

Nrf2-target gene expression is up-regulated by AD2 and NST domains of Nrf1 within chimaeras N607:C270^Nrf2 and Nrf1β^N607:C270^Nrf2, but is also down-... by Yiguo Zhang (512679)

“…These expression constructs for Nrf2 and its chimaeric proteins, together with <i>P_SV40Nqo1</i>-ARE-Luc and β-gal reporters, were co-transfected into either COS-1 cells (<i>right panel</i> of <b><i>D</i></b>) or RL-34 cells (<b>E</b>), before luciferase activity was assayed and the data are presented as fold changes (mean ± S.D). …”

Extinction on biophysical fitness landscape. by C. Scott Wylie (145239)

“…<p>All finite populations eventually go extinct. The mean number of generations until extinction (<i>τ</i>) increases with population capacity (<i>N</i>) and decreases with mutation rate (<i>U</i>). …”

The effect of geniposide on Aβ_1-42-induced Bax and Bcl-2 proteins abnormally expression level. by Chunhui Zhao (309390)

“…Pretreatment of primary cortical neurons with geniposide (2.5–10 μM) could upregulate Bcl-2 expression (B), downregulate Bax expression (C) and decrease the Bax/Bcl-2 ratio (D) induced by Aβ_1–42. …”

Maternal iron restriction prior to conception is associated with embryonic iron deficiency, postnatal anemia, and reduced postnatal central nervous system iron levels. by Camelia Mihaila (354659)

“…<b>E</b>. AAS at postnatal day 45 showed reduced iron level in ID spinal cord and cerebellum compared to CTL samples (spinal cord: n = 8 <i>CTL</i> and n = 5 <i>ID -2wks</i> samples; cerebellum: n = 5 <i>CTL</i> and n = 5 <i>ID -2wks</i> samples; each <i>CTL</i> and <i>ID -2wks</i> group contained tissue samples harvested from 3 separate litters, Mean +/− SEM, * p<0.05).…”

Phosphorus dynamics in a highly polluted urban drainage channel-shallow reservoir system in the Brazilian semiarid by GERMÁRIO M. ARAÚJO (7290242)

Replication of challenge viruses in mice immunized with the VN1203ΔNS1 virus. by Julia Romanova (225341)

“…The limit of virus detection was 1.5 log₁₀ TCID₅₀/ml. Tissues where no virus was detected were defined as 1.5 log₁₀ TCID₅₀/ml for the calculation of the mean titer.…”

The Effect of Gestational Age on Angiogenic Gene Expression in the Rat Placenta by Kanchan Vaswani (504137)

“…Sprague Dawley dams were sacrificed at E14.25, E15.25, E17.25 and E20 (n = 6 per group) and RNA was isolated from one placenta per dam. …”

Table_1_Knowledge and Response to Stroke Among Lebanese Adults: A Population-Based Survey.DOCX by Sylvia Saade (12749600)

“…Multivariable linear regression models were conducted to examine socio-demographic, social habits, and clinical factors independently associated with the SKT and the STAT scores.</p>Results<p>The mean SKT score of the participants was 9.16. 48.5% showed a poor stroke-related knowledge level and 51.5% a good knowledge level. …”