Ara-C-induced Mcl-1 degradation and cell death are inhibited upon TPA-induced ERK activation in BL41-3 cells. by Shanna K. Nifoussi (128297)

“…A representative experiment is included (upper photograph) along with the average (± SE) of 5 independent experiments. Also shown for comparative purposes is the percentage of cells exhibiting morphological apoptosis, assayed with a concentration of 1 nM TPA applied 1 hour before the addition of Ara-C (mean of 3 independent experiments ± SE run in parallel with previous studies; some of the BL41-3 cell samples not treated with TPA were included in a previous publication comparing these to BL41 parental cells (Fig. 4 in reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047060#pone.0047060-Vrana2" target="_blank">[23]</a>). …”

Metformin reduces lipid stores and causes intestinal fluid imbalance. by Cathy Slack (251729)

“…(<b>B</b>) Metformin treatment of female flies does not affect the number of fecal deposits produced per fly over a 24 hour period (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). (<b>C</b>) Metformin treatment of female flies does not affect the size of fecal deposits as measured by the mean area of deposits (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). …”

Calcium levels in PC12 cells exposed to SMF, the A_2AR agonist CGS21680 or antagonist ZM241385. by Zhiyun Wang (360002)

“…(<b>B</b>) In a separate experiment cells were evaluated at the three hour time point when the largest difference between SMF-treated and untreated cells occurred but before cell integrity was compromised from the assay conditions (e.g., from using Ca²⁺ and Mg²⁺ free D-PBS). …”

Dynamic Recruitment of Protein Tyrosine Phosphatase PTPD1 to EGF Stimulation Sites Potentiates EGFR Activation by Pedro Roda-Navarro (604376)

“…Interference of PTPD1 expression caused a decrease in EGFR phosphorylated species at the periphery of the cell. …”

Ovaries from <i>timp</i> mutant females are smaller and lack integrity. by John R. Pearson (847849)

“…Note the marked decrease in the number of developing cysts within the germarium. …”

Auditory and vestibular symptoms after COVID-19 infection: a preliminary Brazilian report by Rubens Jonatha dos Santos Ferreira (12826751)

Elimination of surface contamination. by Sophie Champlot (241494)

The T_Ms of the light scattering, PIA excimer fluorescence, and unfolding. by Abhishek Singh (1454935)

The effect of Metformin on sleep-wake behaviour, basal ATP and food intake. by James H. Catterson (244043)

“…The arrows are identically placed within each chart and point to the decrease in morning activity. (<b>B</b>) Locomotor activity (beam crosses) on diets containing difference concentrations of Metformin. …”

Additional performance tests also exhibited persistent deficits/changes after tMCAO. by Jin Zhou (90734)

“…<p><b><u>A</u>:</b> Hindlimb Placement performance deficits were significant and exhibited no spontaneous recovery of function (i.e., no decrease from the original d1 deficit) for the full 10 weeks of observation post-tMCAO. …”

Galangin inhibits proliferation of Hs578T breast cancer cells by Tessa J Murray (20939)

“…<p><b>Copyright information:</b></p><p>Taken from "Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A"</p><p>Breast Cancer Research 2006;8(2):R17-R17.…”

Increased S129-P-α-synuclein in acutely treated curcumin mice. by Kateri J. Spinelli (293686)

“…(D) Analysis of GFP/S129-P colocalization (CoLoc channel), and quantification of the Pearson’s Colocalization Coefficient (E), shows a decrease in S129-P at GFP-positive terminals. …”

Average pre-pulse inhibition (PPI) of the acoustic-startle response to pre-pulse frequency shifts. by Laetitia Mwilambwe-Tshilobo (793415)

“…(D-F) PPI due to decreasing frequency shifts from a 22 kHz background tone at baseline and at 1, 4, and 8 weeks post-exposure. …”

Ca²⁺ sparklets in DSM are affected by, but not dependent upon, signals from the SR. by Peter Sidaway (190696)

“…In the presence of the VGCC antagonist R-(+)-Bay K 8644 (1 μM) and CPA (10 μM), there was a significant decrease in the frequency (D) but not amplitude (E) of Ca²⁺ sparklets. …”

POLGdn expression led to the depletion of mtDNA-encoded respiratory chain components. by Weiqin Lu (166093)

“…(D) Assay of mtDNA-encoded COII RNA expression by northern blot analysis. (E) Detection of mitochondrial DNA-encoded COII protein by Western blot assay.…”

Huntingtin Fragments and SOD1 Mutants Form Soluble Oligomers in the Cell by Yang-Nim Park (85865)

Increased CPEB4 protein level in most HCC specimens. by Li-Yun Tsai (503512)

“…Five of 8 CPEB4-downregulated samples with decreased expression of E-cadherin were denoted with number signs (#). …”

Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry by Sylvia Haas (414005)

“…The proportion of patients with TTR≥65% varied from 16.7% in Asia to 49.4% in Europe. There was a 2.6-fold increase in the risk of stroke/SE, 1.5-fold increase in the risk of major bleeding, and 2.4-fold increase in the risk of all-cause mortality with TTR<65% versus ≥65% after adjusting for potential confounders. …”

Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry by Sylvia Haas (414005)

“…The proportion of patients with TTR≥65% varied from 16.7% in Asia to 49.4% in Europe. There was a 2.6-fold increase in the risk of stroke/SE, 1.5-fold increase in the risk of major bleeding, and 2.4-fold increase in the risk of all-cause mortality with TTR<65% versus ≥65% after adjusting for potential confounders. …”

Chromosomal integration of HPV16 genomes causes host transcript modulation without host:host interaction changes within TADs. by Ian J. Groves (8703930)

“…Presented charts indicate the transcript level of host protein coding genes within the 1.5 Mb region of W12 clone D2 relative to (D) W12 episomal (Par1) levels and (E) the mean transcript levels of all other integrants used in the study. …”