PF-06446846 does not cause widespread ribosomal stalling. by Nathanael G. Lintner (3850333)

“…<p>(A–D) Metagene plots showing the normalized mean read counts at the nucleotide (nt) positions relative to the start and stop sites for cells treated with 1.5 μM PF-06446846 (red trace) and vehicle (blue trace) for (A–B) 10-min treatment and (C–D) 1-h treatment. …”

The inactivation of <i>Kdm6a</i> in mice had age- and gender-dependent effects on normal hematopoiesis. by Ling Tian (107492)

“…Aged KO-F mice developed a mild macrocytic anemia, which was characterized by decreased hemoglobin (Hb: 11.5 g/dL in KO-F mice vs. 14.28 g/dL in WT-F mice, p = 0.0137) with an increased mean corpuscular volume (MCV: 51 fL in KO-F mice vs. 40.55 fL in WT-F mice, p = 0.0001) and mean corpuscular hemoglobin (MCH: 15.15 pg in KO-F mice vs. 12.85 pg in WT-F mice, p = 0.0004). …”

RanBP2 represses IL6 expression by promoting AGO1 stabilization. by Qingtang Shen (200108)

“…Also note that DMSO-treated RanBP2-dE3 cells had no detectable AGO1. MG132-treatment led to an increase in AGO1, AGO2 and mutant RanBP2-dE3 levels. …”

Vaccine induced protection against leukopenia. by Simon P. Graham (59745)

“…<p>Leucokyte numbers remained at pre-vaccination levels throughout the experiment in animals vaccinated five days prior to challenge with A) UK2000/7.1 or B) CBR/93 (filled circles), whereas a significant (P<0.05) decrease occurred rapidly after challenge in unvaccinated animals (open circles) and animals vaccinated one day before challenge that developed clinical signs and were euthanized prior to the end of the experiment (open triangles). …”

LRP1 endocytosis is required for Aβ42 uptake and accumulation in N2a cells. by Rodrigo A. Fuentealba (362971)

“…The surface-to-total ratio were calculated and plotted as fold-change to control-infected cells. <i>Right panel</i>, decreased CHC levels and normal mLRP4 levels in transduced N2a-mLRP4 cells were verified by Western blot from sister cultures. …”

Table 1_Urinary and oral microbiota in Polish women: a pilot case-control study of breast cancer.docx by Anna Marciniak (12354534)

“…</p>Results<p>BC case urine microbiota contained an increased abundance of Corynebacterium (5.2-fold, but not significant) and Gammaproteobacteria including unknown genus and Pseudomonas (1.7- and 1.8-fold) and decreased abundance of Family XI (0.3-fold) and Bifidobacteriaceae (0.4-fold) compared to HCs. …”

Comparing water-level policies in a boreal reservoir: How wave and ice energy can help maintain walleye spawning habitat by Jason T. Papenfuss (3994103)

Evaluation of hematology, general serum biochemistry, bone turnover markers and bone marrow cytology in a glucocorticoid treated ovariectomized sheep model for osteoporosis researc... by CATARINA A. COELHO (10365236)

Foxm1 expression during heart development. by Craig Bolte (299486)

“…Mean±SEM was determined from 5 random sections at E14.5 and P7 with 3 hearts in each group. qRT-PCR of total heart RNA demonstrated a decrease in Foxm1 mRNA from E14.5 to P20 and Foxm1 mRNA was undetectable in the adult heart (R). …”

Impact of As and taurine on cell viability, ROS production, Δψ_m and intracellular ATP levels. by Joydeep Das (361941)

“…<p>Panel A: Dose dependent effect of As on cell viability; Panel B: Dose dependent effect of taurine on As treated hepatocytes; Cont: cell viability in normal hepacytes; As-2.5, As-5, As-7.5, As-10, As-12.5 and As-15: cell viability in As treated hepatocytes for 8 h at a dose of 2.5, 5, 7.5, 10, 12.5 and 15 µM; TAU-10, TAU-20, TAU-25, TAU-30, and TAU-40: cell viability level in hepatocytes treated with taurine (1 h prior to As addition) and As for 8 h at a dose of 10, 20, 25, 30 and 40 mM. …”

(S)-2 induced growth arrest in LNCAP cells. by Anna Laurenzana (296271)

“…(<b>B</b>, middle) – Phase contrast pictures of companion cultures indicated that (S)-2 induced morphological changes and a marked decrease in cell density. (<b>B</b>, bottom) – Cells were treated with 2.5 µM drug for the indicated time points and p21 protein levels were monitored by immunoblotting; GAPDH was also examined to ensure equal loading of samples in each lane. …”

miRNAs that are most highly regulated in proliferating CD4⁺ T cells. by Connie L. Sommers (426576)

Table1_The feasibility and safety of his-purkinje conduction system pacing in patients with heart failure with severely reduced ejection fraction.docx by Chengming Ma (15775178)

“…In addition, clinical and echocardiographic (≥5% improvement in LVEF or ≥15% decrease in LVESV) responses were assessed. …”

Supplementary Material for: Urea Reduction in Acute Kidney Injury and Mortality Risk by Chávez-Íñiguez J.S. (11189730)

“…<b><i>Results:</i></b> A total of 651 AKI patients were enrolled. The mean age was 54.1 years, and 58.6% were male. AKI 3 was present in 58.5%; the mean admission urea was 154 mg/dL. …”

Presentation1_The feasibility and safety of his-purkinje conduction system pacing in patients with heart failure with severely reduced ejection fraction.pptx by Chengming Ma (15775178)

“…In addition, clinical and echocardiographic (≥5% improvement in LVEF or ≥15% decrease in LVESV) responses were assessed. …”

NK cells are affected differently by allogeneic grafts depending on the course of rejection. by Oliver Beetz (6786137)

“…The ratios of NK cells are presented as mean ± SEM of three (in D) and at least five (in B) recipients. …”

Maternally and paternally acting Pol IV have antagonistic effects on endosperm gene expression. by Prasad R. V. Satyaki (12369421)

“…Plots D and E show median and interquartile range for log₂(fold change) in mutant/WT. …”

Table1.DOCX by Kemin Yan (4924420)

“…Furthermore, uncoupling protein 1 (UCP1) protein levels in the eWAT and pWAT of the IT rats also increased to 2.2- and 2.3-fold of the Sham-IT rats (P < 0.05). …”

Table2.DOCX by Kemin Yan (4924420)

“…Furthermore, uncoupling protein 1 (UCP1) protein levels in the eWAT and pWAT of the IT rats also increased to 2.2- and 2.3-fold of the Sham-IT rats (P < 0.05). …”

Differential accessibility of peaks with transcription factor motifs in response to VSG. by Blaine Harlan (11890751)

“…The 13,449 peaks with positive fold change indicate increased accessibility in VSG; the 4,943 peaks with negative fold change indicate decreased accessibility in VSG. …”