Effects of sodium and calcium channel activity alterations in hiPSC-CMs. by Ashish Mehta (204090)

“…*p<0.05 vs control and ^#p<0.05 vs Bay group. Data represented as mean ± SEM of three independent experiments. Abbreviations- BK- Bay K8644; V- Verapamil; B- Baseline; W- Washout.…”

Effects of <i>in vitro</i> treatment with fadrozole on prolactin-positive cells. by María José García Barrado (590761)

“…Scale bar: a,b,c: 50 µm. d) Plot showing the decrease in cellular area at the different time-points assayed; from 3 to 12 hours of treatment with testosterone and fadrozole a significant decrease (*p<0.01) was observed. e) The percentage of prolactin-positive cells decreases as from 3 to 12 hours of treatment with testosterone and fadrozole (*p<0.01). f) The percentage of PCNA- and prolactin-positive cells, out of the total number of prolactin-positive cells, decreases significantly from 1 to 12 hours of treatment with testosterone and fadrozole (*p<0.01).…”

Real-world Evidence of Efficacy and Safety of Sodium–Glucose Cotransporter 2 Inhibitors as Adjunctive Therapy in Adults With Type 1 Diabetes: A European Two-Center Experience by Ana Palanca (796358)

“…</p> <p><b>Results:</b> Overall, significant reductions in HbA1c (-0.5%), weight (-2.9 kg), and mean daily insulin (-8.5%) were achieved after 12 months. …”

Pol II occupancy is reduced at genes affected by P-TEFb depletion. by Olle Dahlberg (645665)

“…(<b>B</b>) Western blot with extracts from 0–5h old embryos show a decrease in Ser2-P in embryos depleted of maternal Cdk9 or CycT. …”

Radiation induces early alterations in NMDAR phosphorylation and internalization of NR1 and NR2A subunits. by Peter H. Wu (321655)

“…Surface receptors were separated by pull down with neutravidin beads and resolved by western blot. (NR1, 24.5±4.8% decrease in surface, NR2A, 23.4±5.9%, *p = 0.01 and 0.03 respectively, n = 10; NR2B 7.1±9.6%, GluR1 4.9±8.7%, p>0.25, n = 10; GluR2/3 2.97±8.8%, p = 0.89, n = 5).…”

miR-34a pulls down transcripts of known and novel direct targets of miR-34a. by Ashish Lal (43926)

“…Genes whose mRNAs are more highly enriched in the pull-down are progressively more likely to have reduced expression. (E) Pull-down of 11 mRNAs randomly selected from the set of genes enriched ≥2.5-fold by microarray in both HCT116 and K562 Bi-miR-34a pull-downs is confirmed by qRT-PCR relative to <i>SDHA</i> in K562 cells transfected for 24 hr with Bi-CTL (black) or Bi-miR-34a (white). …”

Table_1_Management of Donor-Specific Antibodies in Haploidentical Transplant: Multicenter Experience From the Madrid Group of Hematopoietic Transplant.pdf by Rebeca Bailén (10430765)

“…</p>Results<p>We identified a total of 20 haplo-HSCT in 19 patients performed with DSAs in 5 centers. 10 (53%) patients presented anti-HLA class I DSAs (6 of them with > 5000 mean fluorescence intensity (MFI)), 4 (21%) presented anti-HLA class II (1 with > 5000 MFI) and 5 (26%) presented both anti-HLA class I and II (5 with > 5000 MFI). 90% of patients received at least two treatments as desensitization strategy and all experienced a decrease of MFI after desensitization (mean reduction 74%). …”

Data_Sheet_1_Evaluation of Brain Death in Laying Hens During On-Farm Killing by Cervical Dislocation Methods or Pentobarbital Sodium Injection.docx by Elein Hernandez (6678440)

“…Within 15 s after administration of pentobarbital sodium, there were significant decreases in mean frequency bands, increases in mean F50 and F95, and decreases in Ptot, suggesting brain death. …”

Mechanisms involved in the regulation of CD36 expression by tumor necrosis factor (TNF)α by Jean Frédéric Boyer (32017)

“…Human monocytes were incubated with macrophage-serum-free medium (M-SFM) alone (control), or with M-SFM containing TNFα (10 ng/ml) for 5, 30 or 60 minutes, and then stimulated, or not, with a synthetic ligand of PPARγ, rosiglitazone (R; 5 μmol/l) for 45 minutes. …”

Measuring mean promoter activity and cell-to-cell variability for a library of Zap1 target promoters. by Lucas B. Carey (289856)

“…(E and F) Noise and noise strength graphed against mean expression for each promoter that changes expression by more than 2-fold. …”

Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling-6 by Troels Schepeler (79446)

LANA31-GFP-IBD reverses effect of combined LEDGF/p75 depletion and GFP-IBD dominant interference. by Anne M. Meehan (261905)

“…TL4 cells demonstrate a 456-fold decrease in HIV-1 infectivity. LANA31-GFP-IBD effects a 200-fold rescue, functioning comparably to re-expressed LEDGF/p75 and in contrast to the LANA31-GFP-IBD^D366N. …”

MOs treatment modulates oxidative stress markers in CNS. by Arshed Nazmi (215284)

“…Alterations in TRX-1 levels were similar to that observed in SOD-1 except that its level in JEV+ SC-MO was not significantly different than only JEV-infected group (B&E). Nearly 2-fold increases were observed in NO levels of JEV-infected and JEV+SC-MO groups when compared to those obtained from Sham. …”

Effect of exposure to JC1 and Hoechst on proliferation of cultured transformed and primary tissue cells. by J. Mario Wolosin (465629)

“…In the Hoechst-treated K562 cells, cell count decreased gradually over the three day period while the SSC, which has already increased during the 90 min treatment period (Δ = 56%), continue to increase becoming after 3 days 2.5 higher than the control. …”

Table_1_Multivariate piecewise linear regression model to predict radiosensitivity using the association with the genome-wide copy number variation.xlsx by Joanna Tobiasz (11816504)

“…The weighted mean relative errors (MRE) decreased with increasing the segments' number. …”

Supplementary Material for: Calcium-Alkali Syndrome Associated with Hypoparathyroidism Following Total Thyroidectomy by Kuroya S. (8343321)

“…We defined hypercalcemia as a corrected serum calcium level (cCa) ≥10.5 mg/dL, metabolic alkalosis as a difference in serum sodium and serum chloride ([sNa-sCl]) ≥39 mEq/L, and renal impairment as a ≥50% increase in serum creatine and/or ≥35% decrease in estimated glomerular filtration rate (eGFR) compared to baseline. …”

Expression of Lyn^WT and Lyn^Y397F in 663 cells. by Olivier Kosmider (372523)

“…Data are mean±SD of five independent experiments performed in triplicate. …”

Nonmetric multidimensional scaling (NMDS) ordination of plant community structure and correlations with selected vegetation characteristics (a) and environmental characteristics (b... by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

Impact of fruit-tree shade intensity on the growth, yield, and quality of intercropped wheat by Xu Qiao (4600141)

“…The photosynthetic rate of wheat in the jujube-, apricot-, and walnut-based intercropping systems decreased by, respectively, 11.3%, 31.9%, and 36.2% compared to monoculture wheat, and the mean number of fertile florets per spike decreased by 26.4%, 37.4%, and 49.5%. …”

Age-specific incidence, treatment, and survival trends in esophageal cancer: a Dutch population-based cohort study by Ali Al-Kaabi (7437800)

“…In adults <50 years, EAC incidence tripled (mean increase per year: males 1.5%, females 3%), while the incidence of ESCC decreased (mean decrease per year: males −5.3%, females −4.3%). …”