The Genetics of Reading Disability in an Often Excluded Sample: Novel Loci Suggested for Reading Disability in Rolandic Epilepsy by Lisa J. Strug (151135)

STOX1A induces changes in several major cell cycle regulatory genes. by Daan van Abel (214754)

“…<p>(A) The effect of stable STOX1A overexpression in the SH-SY5Y neuroblastoma cell line on four major mammalian cell cycle regulatory genes was determined with quantitative RT-PCR showing a mean 1,4 fold (mean ΔΔCt is −0,49) and mean 1,72 fold (mean ΔΔCt is −0,78) increased mRNA expression for CCNA2 and CCNB1, respectively, and a mean 1,22 fold (mean ΔΔCt is −0,29) decreased mRNA expression for CCNC in STOX1A stably transfected cell compared to their negative controls. …”

Nilotinib induces apoptosis and cell cycle arrest in HEI-193 cells at clinically-relevant concentrations. by Nesrin Sabha (127278)

“…(C) In GM, the proportion of cells in G1-phase is increased and the proportion in G2/M decreased at ≥5 µM nilotinib. Shown, mean of two replicate experiments.…”

Defective basal immune gene expression and p38 MAP kinase activation in the <i>fat-3(wa22)</i> mutant. by Madhumitha Nandakumar (269242)

“…Data are depicted as mean±s.e.m and represent fold expression in mutant animals relative to wild-type under the same conditions, with wild-type set to one. …”

Advances in Linking Wintering Migrant Birds to Their Breeding-Ground Origins Using Combined Analyses of Genetic and Stable Isotope Markers by Amy A. Chabot (141106)

“…Area of origin decreased by 3 to 5-fold on average, but ranged up to a 10-fold improvement. …”

THS exposure in conjunction with western diet increases oxidative stress. by Neema Adhami (516427)

“…In addition, THS-exposed mice on “western diet” have a decreased ratio of available NADP+ to NADPH compared to that of controls and THS-exposed mice <b>(E)</b>. …”

17β-Estradiol enhances p53 interaction with Mdm2 and p53 ubiquitination. by Limor Raz (199231)

“…*<i>p</i><0.05 vs. Pla. <b>(C)</b> 17β−E₂ increases p53-Mdm2 binding two fold as compared to placebo-treated control levels at 6 h after cerebral ischemic injury. …”

Effects of miR162a on <i>dmTOR</i> gene expression and <i>Drosophila</i> phenotypes. by Kegan Zhu (4404883)

“…Data are represented as the mean ± SEM. ***p < 0.001, Student’s <i>t</i>-test. …”

Ventromedial PFC pattern-separates cue-task associations. by Guochun Yang (1329693)

“…<p>The left 10r area shows that pattern similarity among different cues decreases over time. (A) The anatomical location. (B) A scatter plot of trial similarity as a function of trial number relative to the transition point and the corresponding fitting lines. …”

Trade-off in the performance with respect to slowness and sparsity. by Jörn-Philipp Lies (531530)

“…The ISSA filters at the break even point are shown in (B) for movies, in (C) for translations, in (D) for rotations, and in (E) for scalings. …”

L-type calcium current in WT versus NCX1 KO SAN cells. by Sabine Groenke (488381)

“…<b>B</b>. Mean current-voltage plots (± SEM) showing a significant decrease in peak Ca current in KO (*<i>P</i><0.05 by post-hoc analysis of 2-way ANOVA). …”

SrbB is a transcriptional regulator of genes involved in carbon metabolism, lipid metabolism, and heme biosynthesis. by Dawoon Chung (655511)

Effects of various parameters in spreading of cooperative behavior. by Sourav Roy (389598)

“…<p>Subfigure (a) reveals two contrasting scenarios, where the cooperators decrease with the increment of the mutation rate <i>μ</i>. …”

Time traces of the end-to-end length of DNA. by Rifka Vlijm (133750)

“…Since this molecule is nicked, no supercoils can be formed. Again, a length decrease is observed. <b>F </b><i>NAP1, all 4 core histones, coilable DNA molecule:</i> Same as in E, but in this example the molecule did not have a nick, so supercoils were formed upon nucleosome assembly. …”

Cordycepin-resistance strains are not cross resistant to suramin, pentamidine and melarsoprol. by Suman K. Vodnala (261272)

“…A, F Four months after incubation with cordycepin, parasites reached a 40–60 fold decreased sensitivity to cordycepin. B, G Resistance to different concentrations cordycepin after 4 week-long culture of resistant parasites in absence of the drug is shown. …”

TCR-like Fabs Bind Cognate pMHC with Nanomolar Affinity. by Keith R. Miller (141522)

“…Each binding curve represents a different concentration of pMHC beginning at 200 nM and decreasing to 1.5 nM in 2 fold dilutions. No binding was observed for either Fab binding non-cognate pMHC molecules up to 400 nM.…”

Comparison of current amplitudes from mutant and WT mBest2 Cl⁻ channels. by Agata Kranjc (253149)

“…E306A had a mean value not significantly different from WT (P = 0.5; N = 7–8). …”

Data_Sheet_1_Causal Associations of Urate With Cardiovascular Risk Factors: Two-Sample Mendelian Randomization.docx by Thitiya Lukkunaprasit (9548637)

“…</p>Results<p>The statistically driven approach showed significant causal effects of urate on HDL-C and triglycerides using four of the six MR methods, i.e., every 1 mg/dl increase in genetically predicted urate was associated with 0.047 to 0.103 SD decrease in HDL-C and 0.034 to 0.207 SD increase in triglycerides. …”

The effects of Nodal on proliferation and apoptosis are dependent on activation of the type 1 receptor (ALK4/7). by Daniela F. Quail (123286)

“…(E) PCR analysis demonstrating that treatment of MDA-MB-231 cells with 10 µM SB431542 causes a significant increase in <i>BAX</i> expression (n = 3, p = 0.002), and (F) a significant decrease in <i>BCL2</i> expression (n = 3, p = 0.022), indicative of elevated apoptosis compared to vehicle controls. …”

Extracellular acidification delays neutrophil apoptosis and reduces caspase 3 activation. by Shannan Cao (792360)

“…Purified neutrophils were labeled with FITC-annexin V and PI after cultured for indicated time and detected by flow cytometer. (D,E) pH changed from acid to neutral at either the 4^th hour(D) or the 12^th hour(E) of cell culture will accelerate the neutrophil death. …”