Disrupting autophagy in <i>tti^s450</i> larvae results in the death of IECs and a reduced lifespan. by Yeliz Boglev (280342)

“…<p>(A) Western blot analysis of lysates of <i>tti^s450</i> larvae (72 hpf) that had been injected at the 1–4 cell stage with an antisense morpholino oligonucleotide (MO) targeted to the start codon of <i>atg5</i> mRNA reveals decreased levels of LC3II compared to untreated and vehicle controls, both in the presence and absence of chloroquine. …”

A Concept of Bayesian Regulation in Fisheries Management - Figure 1 by Noél Michael André Holmgren (653777)

“…If the variance is lower than the mean, the posterior mean will decrease with accumulating catches and effort. …”

OE33 R cells display alterations in mitochondrial-associated gene expression, total cellular energy and energy metabolism pathways. by Niamh Lynam-Lennon (589291)

“…<p>(A) Basal expression of 15 mitochondrial function and energy metabolism-associated genes were altered 1.5-fold in OE33 R cells, when compared to OE33 P. …”

Fig 2 - by Hina Mushtaq (14885903)

“…Isolate HM49 recorded its protease enzyme activity from pH 6 (lowest) reaching its optimum at pH 8 followed by a gradual decrease up to pH 12 (2D). Temperature studies revealed its dynamism broadly in 5°C (lowest) to 40 °C range with its optimum activity being recorded at 20 °C (2E). …”

Data Sheet 1_Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.pdf by Louis Schreel (22385035)

“…</p>Results<p>Beneficial cardiometabolic effects included a decrease in mean Lp(a) of 6.6 mg/dl (−21%), a reduction in mean triglyceride of 40.6 mg/dl (−30%), a reduction in mean apoB of 0.14 g/L (−10,5%) and an increase in mean HDL-C of 3 mg/dL (+5%), a reduction in mean hsCRP of 0.94 mg/L (−45%), a reduction in mean TNF-α of 1.31 pg/ml (−7%), a reduction in mean MDA-LDL of 36.77 U/L (−38%), a reduction in mean nitrotyrosine of 225 nmol/L (−28%), a mean weight reduction of 4 kg (−4,6%), a mean visceral fat reduction of 0.69% (−10%) and a mean fat mass reduction of 3.7 kg (−12%). …”

Data_Sheet_1_The Impact of Cognitive Behavioral Therapy on Peripheral Interleukin-6 Levels in Depression: A Systematic Review and Meta-Analysis.pdf by Haijing Ma (12539866)

“…Taken together, our findings support the notion that CBT influences peripheral IL-6 in individuals with depression and represents a point of commonality with other antidepressant treatment modalities (e.g., antidepressants).…”

IAA application on <i>pin1</i> meristem leads to local tissue softening and pectin de-methyl-esterification in sub-epidermal tissues. by Siobhan A. Braybrook (388465)

“…Each pixel in a rigidity map corresponds to the E_A value obtained from one indentation point. …”

Reducing healthcare-associated infections incidence by a probiotic-based sanitation system: A multicentre, prospective, intervention study by Elisabetta Caselli (304287)

“…PCHS was associated with a significant decrease of HAI cumulative incidence from a global 4.8% (284 patients with HAI over 5,930 total patients) to 2.3% (128 patients with HAI over 5,531 total patients) (OR = 0.44, CI 95% 0.35–0.54) (P<0.0001). …”

Ara-C-induced Mcl-1 degradation and cell death are inhibited upon TPA-induced ERK activation in BL41-3 cells. by Shanna K. Nifoussi (128297)

“…A representative experiment is included (upper photograph) along with the average (± SE) of 5 independent experiments. Also shown for comparative purposes is the percentage of cells exhibiting morphological apoptosis, assayed with a concentration of 1 nM TPA applied 1 hour before the addition of Ara-C (mean of 3 independent experiments ± SE run in parallel with previous studies; some of the BL41-3 cell samples not treated with TPA were included in a previous publication comparing these to BL41 parental cells (Fig. 4 in reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047060#pone.0047060-Vrana2" target="_blank">[23]</a>). …”

Metformin reduces lipid stores and causes intestinal fluid imbalance. by Cathy Slack (251729)

“…(<b>B</b>) Metformin treatment of female flies does not affect the number of fecal deposits produced per fly over a 24 hour period (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). (<b>C</b>) Metformin treatment of female flies does not affect the size of fecal deposits as measured by the mean area of deposits (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). …”

Calcium levels in PC12 cells exposed to SMF, the A_2AR agonist CGS21680 or antagonist ZM241385. by Zhiyun Wang (360002)

“…(<b>B</b>) In a separate experiment cells were evaluated at the three hour time point when the largest difference between SMF-treated and untreated cells occurred but before cell integrity was compromised from the assay conditions (e.g., from using Ca²⁺ and Mg²⁺ free D-PBS). …”

Dynamic Recruitment of Protein Tyrosine Phosphatase PTPD1 to EGF Stimulation Sites Potentiates EGFR Activation by Pedro Roda-Navarro (604376)

“…Interference of PTPD1 expression caused a decrease in EGFR phosphorylated species at the periphery of the cell. …”

Ovaries from <i>timp</i> mutant females are smaller and lack integrity. by John R. Pearson (847849)

“…Note the marked decrease in the number of developing cysts within the germarium. …”

Auditory and vestibular symptoms after COVID-19 infection: a preliminary Brazilian report by Rubens Jonatha dos Santos Ferreira (12826751)

The T_Ms of the light scattering, PIA excimer fluorescence, and unfolding. by Abhishek Singh (1454935)

The effect of Metformin on sleep-wake behaviour, basal ATP and food intake. by James H. Catterson (244043)

“…The arrows are identically placed within each chart and point to the decrease in morning activity. (<b>B</b>) Locomotor activity (beam crosses) on diets containing difference concentrations of Metformin. …”

Additional performance tests also exhibited persistent deficits/changes after tMCAO. by Jin Zhou (90734)

“…<p><b><u>A</u>:</b> Hindlimb Placement performance deficits were significant and exhibited no spontaneous recovery of function (i.e., no decrease from the original d1 deficit) for the full 10 weeks of observation post-tMCAO. …”

Galangin inhibits proliferation of Hs578T breast cancer cells by Tessa J Murray (20939)

“…<p><b>Copyright information:</b></p><p>Taken from "Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A"</p><p>Breast Cancer Research 2006;8(2):R17-R17.…”

Increased S129-P-α-synuclein in acutely treated curcumin mice. by Kateri J. Spinelli (293686)

“…(D) Analysis of GFP/S129-P colocalization (CoLoc channel), and quantification of the Pearson’s Colocalization Coefficient (E), shows a decrease in S129-P at GFP-positive terminals. …”

Average pre-pulse inhibition (PPI) of the acoustic-startle response to pre-pulse frequency shifts. by Laetitia Mwilambwe-Tshilobo (793415)

“…(D-F) PPI due to decreasing frequency shifts from a 22 kHz background tone at baseline and at 1, 4, and 8 weeks post-exposure. …”