Proof of Concept, Randomized, Placebo-Controlled Study of the Effect of Simvastatin on the Course of Age-Related Macular Degeneration by Robyn H. Guymer (168403)

“…</p><p>Methodology/Principal Findings</p><p><u>Objectives:</u> To evaluate the effect of simvastatin on AMD progression and the effect modification by polymorphism in apolipoprotein E (<i>ApoE</i>) and complement factor H (<i>CFH</i>) genes. …”

Daylength. by Mariana Abarca (6792434)

“…Dashed lines correspond to individuals that entered diapause and dotted line to the 5 individuals that did not enter diapause. Black points indicate mean time to each of the five typical larval instars and to pupation (intercalary molts are not shown to improve clarity; development time of intercalary instar “3.5” is considered part of instar 3). …”

Decision boundary dynamics modulated by theta activity. by Nadja R. Ging-Jehli (10925910)

“…For visualization, we show impact of theta at 3 levels (i.e., 1 SD below grand mean, at grand mean, 1 SD above grand mean; but all regressions were done continuously). …”

Accuracy of consumer-level and research-grade activity trackers in ambulatory settings in older adults by Salvatore Tedesco (6029417)

“…A large mean absolute percentage error (MAPE) was found for every monitor at slower walking speeds with the lowest reported MAPE at 2 km/h being 7.78%, increasing to 20.88% at 1.5 km/h, and 44.53% at 1 km/h. …”

Relative gene expression of <i>IL1Β</i> in controls and vitiligo patients. by Naresh C. Laddha (111354)

“…ANOVA's trend test confirmed a significant decrease in the mean ΔCp values for patients (<i>p</i> = 0.035), as compared to controls (<i>p</i> = 0.154). …”

Cell-to-cell heterogeneity measurement using Shannon entropy. by Angélique Richard (3603923)

“…Negative and null delta entropies (i.e., for a given time-point, the entropy value for these genes decreased or does not change, compared to the earlier time-point) are colored in blue and green. …”

Quantitative scoring of collagen II, MMP-13 and ICAM-1 immunohistochemistry. by Julia Lorenz (626379)

“…Sections of Mc1re/e knee joints showed no difference over time. Collagen II stained cartilage area of non-operated 11 weeks old Mc1re/e mice (p = 0.0159) and Mc1re/e mice 4 weeks (p = 0.0159) after OA induction is decreased compared to WT mice. …”

RhoC over-expression altered paxillin distribution and accelerated focal adhesion turnover. by Ningfeng Fiona Li (492081)

“…Scale bar: 5μm.</p> <p>(C-E) Focal adhesion ‘disassembly assay’ (NOC: nocodazole) showed that, compared to Capan 1, nRhoC cells had accelerated disassembly and re-assembly of mature focal adhesions (FA: large 4-5 μm) and small focal adhesion (1μm). …”

Spinal cord staining with GFAP. by Dalal G. Al-Adwani (8190696)

“…The TEGBE (n = 12) <b>(A5, A6)</b>, G-B (n = 12) <b>(A7, A8)</b> and GBE-treated (n = 6) <b>(A9, A10)</b> groups show an observable decrease in the GFAP-immunoreactive astrocytes compared to crush at the week 3 and week 6 post-injury. …”

Transgenic mice with cysteine mutations have defects in T cell development in the thymus. by Yibing Wang (204330)

“…Data shown are for 4 tgε^Mut mice and 8 wt control (cntl) mice (3 BL6, 1 tgε^WTcd3ε^+/−, 1 tgε^Mutcd3ε^+/−, and 3 tgε^WT). For (B–E) cells from the thymus were costained with multiple antibodies against surface proteins (CD4, CD8, B220, CD44, CD25, CD5, and CD69). …”

Unreliable cells contribute more to discrimination of similar odors. by Shyam Srinivasan (522850)

“…Each gray point represents the discrimination measure (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002206#pbio.3002206.e004" target="_blank">Eq 2</a>) for an odor-pair. …”

Data from: The efficacy of inactivated vaccine against H5 clade 2.3.4.4b highly pathogenic avian influenza virus in turkeys by Erica Spackman (17362552)

“…Although turkeys are a smaller sector in poultry production compared to chickens, they tend to be affected more severely by HPAI virus because they can usually be infected with a lower dose of influenza A virus than chickens (i.e., they are more susceptible). Exposure to non-replicating proteins may help control HPAI, however data with turkeys are somewhat limited regarding how well they work and approaches to modifying surveillance have not been developed. …”

Doxorubicin treatment accelerates bone loss in preclinical breast cancer bone metastasis model. by Tapasi Rana (339809)

“…(C) Representative microCT images (3D reconstruction) of tibiae collected from non-tumor bearing and tumor-bearing Balb/C mice after three weeks of treatment and (D) Quantification of average BV/TV showing further decrease in trabecular bone volume in tumor-bearing mice upon doxorubicin treatment, compared to non-tumor bearing mice. …”

The effect of activation variable V_S of CaL on PIC patterns and firing types. by Yi Cheng (317041)

“…Increasing the V_S non-linearly reduced the I_onset and I_offset with a decrease in ΔI. …”

DepMap essential genes exhibit preferential epigenetic conservation. by Daniel Rud (11432670)

“…<b>C)</b> DepMap essential genes (shRNA log-fold decrease less than -0.4) showed significantly smaller gene PWDs than non-essential genes. …”

Autism and Increased Paternal Age Related Changes in Global Levels of Gene Expression Regulation by Mark D. Alter (139909)

English tweet volume and expressed happiness (random 10% sample), 2020–2021. by Henry H. Wu (14380768)

“…The time series is absent at times where “Black Lives Matter” did not receive measurable attention, i.e. it was not within the top million 3-grams. The gray shaded areas represent periods of time when “Black Lives Matter” was among the top 5,000 most used 3-grams per day. …”

Behavioral results of Experiment 2. by Yeonju Sin (11846045)

“…Negative values on the y-axis indicate that decision thresholds decrease between opportunities. Error bars indicate s.e.m.…”

Increased atherosclerotic lesion regression following blockade of JAM-C is concurrent with increased leukocyte emigration from plaques. by Paul F. Bradfield (3149529)

“…<p>48-hrs prior to transplantation or immediate sacrifice, all donor ApoE^-/- mice fed 12-wks of WD were injected with EdU (2mg/kg, i.p) to incorporate into DNA of monocyte precursors proliferating in the bone marrow. …”

Fast two-photon imaging of calcium rise times in spines and dendrites. by L. Niels Cornelisse (67656)

“…The decreases in spines almost match these step increases.…”