EYA inhibitor Benzbromarone, compound 1. by Emmanuel Tadjuidje (325188)

“…Increasing concentration of substrate does not overcome inhibition. Each point represents the mean and standard deviation of two independent readings. …”

Frequency dependent increase in contractile response of isolated detrusor strips in response to trains of 20 pulses at frequencies ranging from 0.25 to 40 Hz in the absence or in t... by Sara Pritchard (4030679)

“…In this tissue both phases of contraction were reduced by atropine while in MPTP tissues, atropine inhibited the second phase to a greater extent at the 4 Hz (e) and 40 Hz (f). Each data point represents mean ± sem (n = 5) * P<0.05.</p>…”

KLK6 promotes survival of Jurkat T cells in part by slowing the apoptotic cascade. by Isobel A. Scarisbrick (354022)

“…<p>To address the effect of KLK6 on apoptosis, Jurkat T cells were grown under resting conditions (A), or in the presence of apoptosis inducing agents (B to D), then labeled with Annexin V-PE and 7AAD prior to flow cytometry. Under resting conditions (A), and in the presence of camptothecin (B, 1.0 µM), ConA (C, 5 µg/ml), or ConA plus camptothecin (D), KLK6 (10 µg/ml) promoted an increase in the percentage of live cells (unlabeled) and a decrease in the percentage of dead cells (Annexin V⁺ and 7AAD⁺) at both acute (4 hr), subacute (24 hr), and in some cases the more chronic time point examined (48 hr). …”

Chronic intermittent ethanol (CIE) exposure alters the time course of STDP. by Sven Kroener (321008)

“…This was due both to a decrease in potentiation at the late time-point and to the continued increase in LTP in both CIE-exposed groups of mice. …”

Data_Sheet_1_Identification of a New de Novo Mutation Underlying Regressive Episodic Ataxia Type I.DOCX by Zeynep S. Karalok (5556416)

“…The conserved glycine is located in the S4–S5 linker, a crucial domain controlling Kv1.1 channel gating. …”

Supplementary Material for: Impact of Lung Biopsy on Lung Function in Idiopathic Pulmonary Fibrosis by Aussedat P.-H. (9711755)

Effects of PACAPs and/or oxidative stress on NFAT4, calcineurin expression and activity in chondrifying cells. by Tamás Juhász (195396)

“…<p>PACAP 1-38 at 100 nM, PACAP 6-38 at 10 µM were applied continuously from day 1. …”

Correlation of Cervical Cancer Mortality with Fertility, Access to Health Care and Socioeconomic Indicators by Diama Bhadra Vale (6879314)

“…In the multivariate analysis, only fertility rate was significantly associated with the CC mortality rate (coefficient of correlation: 9.38; 95% confidence interval [CI]: 5.16-13.59). Conclusion A decrease in the fertility rate, as expected when the level of development of the regions increases, is related to a decrease in the mortality rate of CC. …”

Body image perception and satisfaction in university students by Ingrid Ludimila Bastos Lôbo (10422415)

“…<div><p>Abstract Body image represents the mental perception of body shapes and is a multifactorial structure that includes psychological, physical and emotional elements. …”

Heat map analysis of selected peptides. by Sayani Dasgupta (104387)

“…Bright red indicates peptides that were elevated ≥100% (ratio ≥2.00). The three groups in the heat map indicated by lines and numbers on the left margin indicate peptides which showed a large or partial decrease (set 1), little or no change (set 2), or a large increase (set 3) in response to the proteasome inhibitors. …”

Partial unwinding of backbone modified DNA substrates by BACH1-WT helicase by Rigu Gupta (22923)

“…As the dsDNA is unwound, the dye molecules are displaced (open ovals) which is measured by a decrease in the amount of fluorescence. In Scheme 1, the unmodified DNA substrate is fully unwound by the helicase, resulting in a maximal change in fluorescence. …”

Penile cancer trends and economic burden in the Brazilian public health system by Fernando Korkes (5910167)

“…Conclusion: Despite the decrease in admissions, penile cancer still imposes a significant economic and social burden to the Brazilian population and the Public Health System.…”

Tie-2 Knock-Down Inhibits MLC-p and Promotes Disrupted Endothelial Architecture, Replicating the Effects of Ang-2 by Samir M Parikh (72439)

“…<div><p>(A) HMVECs were stimulated with Ang-2 (100 ng/ml) in 2.5% FBS EBM-2 for the indicated times, and phospho-Tie-2 was detected by immunoprecipitation and Western blot (upper) as described in Methods. …”

Oxygen uptake kinetics and energy system’s contribution around maximal lactate steady state swimming intensity by Jailton Gregório Pelarigo (3801085)

“…Subjects showed similar time delay (TD) (mean = 11.5–14.3 s) and time constant (τ_p) (mean = 13.8–16.3 s) as a function of v, but reduced amplitude of the primary component for 97.5% (35.7 ± 7.3 mL.kg.min^-1) compared to 100 and 102.5%MLSS (41.0 ± 7.0 and 41.3 ± 5.4 mL.kg.min^-1, respectively), and τ_p decreased (mean = 9.6–10.8 s) during the second phase of exercise. …”

Astrocytic volume changes in the cortex of GFAP/EGFP and GFAP/EGFP/α-Syn^−/− mice during hypoosmotic stress. by Miroslava Anderova (155561)

“…The changes of astrocytic volume during washout were evaluated in each individual cell and expressed as an average percent of cell volume increase/decrease related to the maximal volume after 30 minutes of aCSF_H-50 (<b>C right</b>) or aCSF_H-100 (<b>D right</b>) exposure; these values were set as 0%. …”

Validation of the primary screen hits with secondary luciferase-based invasion and red-green invasion assays. by Rajshekhar Y. Gaji (417441)

“…The values obtained with non-targeting siRNA controls were set at 100% invasion. A total of 81 genes (red asterisks) showed significant decrease (<i>p</i><0.05, one sample <i>t</i>-test) in parasite invasion compared to NTsiRNA controls. …”

Expression of MMP7 and TIMP1 in wounds. by Katharina Sommer (463202)

“…Septic animals show a significant decrease in MMP7 expression on day 2 and 6 compared to control mice. …”

Characterisation and influence of the content of waste foundry sand on rendering mortars by Juliana Machado Casali (4696111)

“…The results demonstrated that the waste foundry sand had an influence on the properties of the mortars in fresh state (mainly for the mortar with 100% waste foundry sand, which required the use of a larger amount of water to obtain the same consistence) and in the hardened state (decrease in strength, mass density and modulus of elasticity). …”

Ca²⁺ sparklets in DSM are affected by, but not dependent upon, signals from the SR. by Peter Sidaway (190696)

“…In the presence of the VGCC antagonist R-(+)-Bay K 8644 (1 μM) and CPA (10 μM), there was a significant decrease in the frequency (D) but not amplitude (E) of Ca²⁺ sparklets. …”

Glycosylation inhibitors block thrombin-induced sRBC adhesion to HUVECs. by Pushpankur Ghoshal (580530)

“…The level of sRBC adhesion to untreated HUVECs was set to 100%. **, p<0.0001 <b>B</b>. Glycosylation inhibitors decrease thrombin-induced sRBC adhesion to HUVECs. …”