OSM activates ERK-1/2, SAPK/JNK-1/2 MAP kinases, the PI3-kinase Akt and STAT1/3 in HCT116 cells and STAT3 activation is dependent of the LIFR. by Florian Beigel (174724)

“…<p>(A) Stimulation with OSM (100 ng/mL) resulted in increased phosphorylation of ERK-1/2, SAPK/JNK-1/2 kinases and induced PI3 kinase-dependent Akt phosphorylation. …”

Table 1_The impact of percutaneous endoscopic gastrostomy on nutritional status and survival in cervical esophageal cancer patients undergoing chemoradiotherapy.docx by Zijun Wen (21596450)

“…The 2, 3, and 4 year OS rates for the PEG group were 81.9% (95% confidence interval [CI]: 63.2–100%), 54.3% (95% CI: 25.5–83.1%), and 32.6% (95% CI: 0.0–63.6%), respectively, while the Non-PEG group had 2, 3, and 4 year OS rates of 100% (95% CI: 83.0–100%), 82.1% (95% CI: 59.2–100%), and 49.2% (95% CI: 11.4–87.0%), respectively. …”

Calf circumference: clinical validation for evaluation of muscle mass in the elderly by Valéria Pagotto (4830771)

“…Results: The most accurate cut-off points for detecting decreased muscle mass in the elderly were 34 cm for men (sensitivity: 71.5%, specificity: 77.4%) and 33 cm for women (sensitivity: 80.0%; specificity: 84.6%). …”

Experimental data for Atf3 and Egr1 regulation in cardiomyocytes exposed to ET-1 and modifications to the original mathematical model for the Atf3/Egr1 negative feedback system. by Marcus J. Tindall (243398)

“…<p>A, Experimental data for Atf3 mRNA (solid circles, solid line) and Atf3 protein (open circle, dashed line) levels in cardiomyocytes exposed to 100 nM ET-1 for the times shown. …”

Performance regimes and optimal bias strength. by Clémence Bergerot (19541372)

“…Blue plot: 2 agents; Pink plot: 5 agents. To obtain these plots, we converted each data point from the previous Q-value-gap distributions to a behavior profile <i>via</i> the softmax formula. …”

Data_Sheet_1_Trends in mortality and causes of death among Chinese adolescents aged 10–19 years from 1990 to 2019.ZIP by Jiaxin Zhu (446571)

“…Regarding age, compared with those aged 10–14 years, the mortality rate of adolescents aged 15–19 years had a higher mortality (35.9/100,000 vs. 21.2 in 2019) and a slower decrease rate (percent: −57.6 vs. −63.2). …”

Anthocyanin-rich compounds extracted from bilberry and blackcurrants inhibit <i>in vitro</i> osteoclastogenesis, but not osteogenesis. by Sawako Moriwaki (563407)

“…B: Anti-osteoclastogenic activity of anthocyanin compound was evaluated by the absorption ratio of the red-stained area per well at 520 nm on a spectrometer. C: Primary osteoblastic cells were cultured in the medium containing 50 µg AA, 10 µM Dex and 10 mM β-GP with or without anthocyanin compound for 2 weeks. …”

Microarray analysis of 4HT, endoxifen and ICI action in the absence of estrogen. by John R. Hawse (227611)

“…<p>(<b>A</b>) Venn diagram of genes whose expression levels were determined to be significantly altered by 100 nM concentrations of 4HT, endoxifen or ICI in the absence of estrogen following 24 hours of regardless of fold-change levels. …”

Table 1_Dietary caffeine and its negative link to serum Klotho concentrations: evidence from the National Health and Nutrition Examination Survey.docx by Haimeng Wu (20416217)

“…</p>Results<p>After controlling for covariates, a negative correlation was observed between dietary caffeine consumption and serum Klotho concentrations, with each additional 100 mg of dietary caffeine consumption, Klotho decreased by 3.40 pg.…”

AgTL2 embryos have altered lipids, metabolites, and transcriptional profiles during development. by Maurice A. Itoe (9930475)

“…(C) Heatmap of metabolites analyzed by LC-MS showing levels of the 60 most highly dysregulated metabolites in AgTL2 embryos compared to controls throughout development (values of <i>t</i> test statistic, range: blue to red = significant decrease to increase) (3 biological replicates represented by triplicate columns at each time point). …”

Reactions of NPY+ and ChAT+ interneurons to QA. by Qiqi Feng (535984)

“…Cont is short for control. Scale bars: A–D, 100 μm; A′–D′, 30 μm; B*, 10 μm.</p>…”

Oligodendrocyte ablation modifies the expression of axonal guidance molecules and neuronal plasticity markers. by Sandrine Doretto (221560)

“…Scale bar 100 µm. Quantification (expressed as % of control) of Netrin-1 shows a decrease of its expression in granule cell precursors of the external granular layer; while a concomitant increase of Sema3A expressed by Purkinje neurons is observed in MBP-TK mice versus WT siblings. …”

Changes in the Bacterial Community Structure of Remediated Anthracene-Contaminated Soils by Laura Delgado-Balbuena (3211080)

“…On the one hand, application of earthworms removed most of the contaminant from the arable soil and had a strong effect on the bacterial community structure, i.e. a decrease in the relative abundance of the Acidobacteria, Chloroflexi and Gemmatimonadetes, and an increase in that of the Proteobacteria compared to the unamended soil. …”

Thermo-economic assessment of forward osmosis as pretreatment to boost the performance and sustainability of multi-effect distillation for seawater desalination by Ortega-Delgado, B.

“…Results show that using FO pretreatment in a 100 m3/d MED plant of 8 effects at 65 °C allows increasing the heating steam temperature up to 100 °C and the number of effects to 16 without increasing the risk of scaling. …”
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Assessment of SnO2 nanoparticles' impact on the growth of Picochlorum maculatum algae by Bounnit, Touria

“…To determine the effect of SnO2 nanoparticles on Picochlorum maculatum - isolated from a Qatar marine environment, algal growth media are amended with different nanoparticle concentrations (1, 5, 25, 50, and 100 mg L−1) and the culture was observed for 72 h. …”
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<i>In vivo</i> analysis of the P1' Specificity of the pTEV2 protease. by Christian Renicke (585725)

“…<b>B</b>) Quantification of the P1' Specificity of the pTEV2 protease. Decrease of full length tester construct after two hours was normalized to initial values and relative efficiency normalized to proline was calculated (cleavage efficiency = ([X]_2h/[Pro]_2h×100-100) ×(−1)), assuming that the recognition sequence with proline at the P1’ Position is not cleaved at all. …”

<i>Sox10</i>-GFP^neg OPCs do not rescue the myelination phenotype in adult mice. by Shayan Moghimyfiroozabad (19066182)

“…<p>(A) Low magnification of a coronal brain section of adult mouse immunostained for myelin basic protein (MBP, magenta) and 2′,3′-Cyclic nucleotide 3′-phosphodiesterase (CNP, red) illustrates the almost total absence of myelination in the dorsal forebrain upon genetic ablation of <i>C1ql1</i>-expressing OPCs (upper panel). …”

Trends in prostate cancer mortality in the state of São Paulo, 2000 to 2015 by Carolina Terra de Moraes Luizaga (10434025)

“…RESULTS For the state of São Paulo, age-adjusted mortality rates were 15.2, 13.3 and 11.9 per 100,000 men, respectively, in the periods between 2000 to 2005, 2006 to 2010 and 2011 to 2015, with a significant decrease trend (AAPC = -2.10%; 95%CI -2.42 – -1.79) each year. …”

Supplementary Material for: Identification of Candidate Genes and Pathways in Nonsegmental Vitiligo Using Integrated Bioinformatics Methods by Liu B. (3923441)

“…<i>PPARG</i>, <i>MUC1</i>, <i>S100A8</i>, and <i>S100A9</i> were identified as key hub genes involved in the pathogenesis of vitiligo. …”

Histological evaluation of infected pressure ulcers in diabetic TALLYHO/JngJ mice. by Haroon Mohammad (757134)

“…(d) On closer view, bacteria are less numerous and form small clusters compared to negative controls and collagen fibers are visible (dashed box). Scale bar represents 100 μm. (e) Ebselen-treated animals had a pronounced decrease in bacterial burden compared to the negative control, with few scattered aggregates in the deep dermis (arrows) and normal collagen fiber architecture in between. …”