VCP Inhibition by DBeQ effectively controls H1299 proliferation and migration while inducing apoptosis. by Kyla Walworth (3150936)

“…The Cell Titer AQueous One Solution MTS/MTT reagent (Promega) was added to each well, 1 hour before stopping the experiment and a microplate reader was used to quantify changes in cell viability (n = 5) at the 24-hour time point. Data indicates that DBeQ treatment leads to a more significant (p<0.001) decrease in cell proliferation, as compared to NMS-873. …”

datasheet1_Mutations of N1 Riboswitch Affect its Dynamics and Recognition by Neomycin Through Conformational Selection.pdf by Piotr Chyży (10159391)

“…Indeed, simulations of the unbound riboswitch show that G17 frequently stacks with base 7, while base 8 is stabilized towards the binding site in a way that it may interfere with the conformational selection mechanism and decrease riboswitch regulatory activity. In the riboswitch complexes, this single-point A to G mutation disrupts a strong hydrogen bond between nucleotides 5 and 17 and, instead, a new hydrogen bond between residue 17 and neomycin is created. …”

Table_1_Influences of Canopy Nitrogen and Water Addition on AM Fungal Biodiversity and Community Composition in a Mixed Deciduous Forest of China.docx by Aihua Zhao (136578)

“…We found that (1) in the 1st year, N addition, water addition and their interactions all exhibited significant influences on AM fungal community composition; (2) in the 2nd year, only water addition significantly reduced AM fungal alpha-diversity (richness and Shannon index); (3) in the next 2 years, both N addition and water addition showed no significant effect on AM fungal community composition or alpha-diversity, with an exception that water addition significantly changed AM fungal community composition in the 4th year; (4) the increment of N or water tended to decrease the abundance and richness of the dominant genus Glomus and favored other AM fungi. (5) soil pH was marginally positively related with AM fungal community composition dissimilarity, soil NH₄⁺-N and N/P showed significant/marginal positive correlation with AM fungal alpha-diversity. …”

Token merging module. by Wen-Qing Huang (5258126)

“…Experimental results demonstrate that compared to the baseline model, the proposed enhanced model achieves a reduction of 2.5G Flops computational complexity and a 16% speed improvement on a private pavement disease dataset, with only a 1.2 percentage point decrease in AUC accuracy. …”

Prenylated Polyphenols from <i>Clusiaceae</i> and <i>Calophyllaceae</i> with Immunomodulatory Activity on Endothelial Cells by Caroline Rouger (1523164)

“…Here, 13 polyphenols belonging to 5 different chemical types of secondary metabolites (i.e., mammea coumarins, a biflavonoid, a pyranochromanone acid, a polyprenylated polycyclic acylphloroglucinol (PPAP) and two xanthones) were tested on resting and cytokine-activated EC cultures. …”

Cold shock of <i>Yersinia pseudotuberculosis</i> IP32953. by Xiaojie Jiang (4759644)

“…(B) Relative mRNA expression levels of DEAD-box RNA helicase genes <i>rhlB</i>, <i>csdA</i>, <i>dbpA</i>, <i>rhlE</i> and <i>srmB</i> in three independent cold-shocked (rapid decrease from 28°C to 3°C) cultures compared to pre-cold-shocked cultures at each time point (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0219422#pone.0219422.s003" target="_blank">S3 Table</a>). …”

Table_4_Proteomic analysis reveals semaglutide impacts lipogenic protein expression in epididymal adipose tissue of obese mice.xlsx by Ruiyi Zhu (13963501)

“…Bioinformatics analysis showed a reduction of CD36, FABP5, ACSL, ACOX3, PLIN2, ANGPTL4, LPL, MGLL, AQP7, and PDK4 involved in the lipid metabolism in the Sema group accompanied by a decrease in visceral fat accumulation, blood lipids, and improvement in glucose intolerance.…”

An Atypical Mitochondrial Carrier That Mediates Drug Action in <i>Trypanosoma brucei</i> by Juan P. de Macêdo (735541)

“…Metabolomic analyses of parasites over-expressing TbMCP14 showed increased levels of the proline metabolite, pyrroline-5-carboxylate, suggesting a possible involvement of TbMCP14 in energy production. …”

Gadolinium Retention 10 years after Gd-CM - Gd-Concentrations in Spot - and CEMET Urine by Thomas Clemens Carmine (19756929)

“…</p><p dir="ltr">By six months post-Gd-CM, gadolinium concentrations in spontaneous urine are typically below detectable levels (see also https://doi.org/10.6084/m9.figshare.27131922.v1). By contrast, gadolinium remains quantifiable in CEMET urine, with the rate of decline slowing after this point. …”

Table_2_Proteomic analysis reveals semaglutide impacts lipogenic protein expression in epididymal adipose tissue of obese mice.xlsx by Ruiyi Zhu (13963501)

“…Bioinformatics analysis showed a reduction of CD36, FABP5, ACSL, ACOX3, PLIN2, ANGPTL4, LPL, MGLL, AQP7, and PDK4 involved in the lipid metabolism in the Sema group accompanied by a decrease in visceral fat accumulation, blood lipids, and improvement in glucose intolerance.…”

Action potential amplitude and shape vary with firing rate for the majority of neurons. A by Peter Stratton (158746)

“…These points were then used to calculate spike rise time, fall time and half width (respectively blue, green and red lines on the graphs A2 and A4) for each spike bin. …”

Comparative results of the ablation experiments. by Wen-Qing Huang (5258126)

“…Experimental results demonstrate that compared to the baseline model, the proposed enhanced model achieves a reduction of 2.5G Flops computational complexity and a 16% speed improvement on a private pavement disease dataset, with only a 1.2 percentage point decrease in AUC accuracy. …”

Table1_Interplay Between Coastal Elevation and Wave Height Controls the Occurrence of Coastal Boulder Deposits in the Aran Islands, Ireland.XLSX by Alexis Van Blunk (11476120)

“…We use topographic elevation (Z) and offshore 100-years significant wave height (H_s,100) to calculate a dimensionless elevation Z* = Z/H_s,100 at 25 m intervals all along the Atlantic-facing coasts of the Aran Islands, and record whether CBD were present or absent at each location. …”

Table_1_Insights into melatonin-induced photosynthetic electron transport under low-temperature stress in cucumber.xlsx by Pei Wu (327833)

“…Under low temperature stress conditions, 100 μmol · L^-1 (MT 100) improved the performance of the active photosystem II (PSII) reaction centers (PIabs), the oxygen evolving complex activity (OEC centers) and electron transport between PSII and PSI, mainly by decreasing the L-band, K-band, and G-band, but showed differences with different duration of low temperature stress. …”

data-raw.xls by Jinlei Zhu (19952964)

“…The daily mean value and daily accumulation of sap flow followed the order: 50% stumping > control (no stumping) > 75% stumping > 100% stumping. Sap flow velocity and daily sap flow accumulation increased at 50% stumping but decreased at 75% and 100% stumping. …”

Table_1_Trends in the Epidemiology of Leishmaniasis in the City of Barcelona (1996–2019).DOC by David Palma (4968895)

“…A higher incidence was observed in the 0–4-year-old group (1.73 per 100,000 inhabitants), but increased during the study period for all age groups. …”

Impact of Pulsed Dielectrophoretic Supply on the Function of Microorganisms in Membrane Bioreactors by Larbi B.

“…At high electrical potentials (100 and 150 V), the microbial activity decreased as a result of the increased current flow and temperature build up due to the Joule heating effect. …”
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Both IKKα and IKKβ contribute to doxorubicin-induced phosphorylation of p65 and doxorubicin induces nuclear accumulation of p52. by Brian K. Bednarski (259893)

“…(B) Cytoplasmic and nuclear extracts were isolated from U2OS cells treated with doxorubicin (Dox) +/− Compound A (Cmpd A) for 6 hours. Immunoblot for p52/p100 confirms an increase in the nuclear translocation of p52 in response to Dox treatment. …”

Analysis of Composite Membranes in the Separation of Emulsions Sunflower oil/water by Dionisio da Silva Biron (10443312)

“…Membranes impregnated with PA66 showed a sunflower oil retention between 53.5 and 99.5% and superior membrane resistance (MR) to the permeate flux (1.92 x 1013 a 5.52 x 1013) which explains the decrease in the permeate volume.…”

MTT cell proliferation assays by Vasilis Androutsopoulos (51786)

“…Cytotoxicity of eupatorin in MDA-MB-468 cells and MCF-10A cells. Decrease of eupatorin cytotoxicity in MDA-MB-468 cells after addition of acacetin. …”