Molecular pathways underlying degeneration in synapse-enriched fractions are conserved across diverse neurodegenerative conditions. by Thomas M. Wishart (138237)

“…Representative bands from quantitative fluorescent western blot experiments on synapse-enriched fractions from wild-type (WT) and R6/2 mice. C. Bar chart (mean±SEM) showing quantitative fluorescent western blot data for protein expression levels in synapse-enriched fractions from the cerebellum generated from a mouse model of spinocerebellar ataxia type 5 (βIII-spectrin KO mice) compared to wild-type controls (N≥3 mice per genotype). …”

Collapse regime, hysteresis, and recovery of plant–pollinator mutualistic networks. by Gaurav Baruah (7257587)

“…(B, C) As the transition parameter, which is <i>γ</i>₀, decreases, the mutualistic network transitions from a high-functioning stable state—high species richness in B and high biomass in C—to a low-functioning undesirable state—low richness in B and low biomass depicted by dark pink points. …”

Dynamics of the Ca²⁺ depletion waves. by Mitra Esfandiarei (280455)

“…As the distance from the point of origin increases, the wave velocity decreases asymptotically to zero. <b>C)</b> Average values for <i>R/R₀</i> and [Ca²⁺]_SR at the rim of the depletion wave also decreases as the wave expands over time (ROI = 5, n = 5 independent experiments, mean ± SEM, <i>P</i><0.005).…”

Ischemia depresses the amplitude of evoked synaptic transmission without changes in the presynaptic volley amplitude. by Shirin Jalini (2551054)

“…<p>(A). fEPSPs were recorded from the stratum radiatum in the CA1 region while the Schaffer collaterals were stimulated every 15 s. fEPEP amplitude decreased reversibly in a time-dependent manner after 2 min (n = 7), 4 min (n = 5), and 6 min (n = 5) of OGD. …”

Involvement of clathrin-mediated endocytosis in NTBI uptake by PBMCs and HepG2 cells. by Joao Arezes (488491)

“…<p>(A–B) ⁵⁵Fe uptake by PBMCs and HepG2 cells in the presence of 0.45M of sucrose (A) or 80 µM of Dynasore (B) to inhibit clathrin-mediated endocytosis, after incubation with 5 µM of ⁵⁵Fe-citrate (5∶100) at 37°C (C–D) ¹²⁵I-Transferrin internalization in the presence of 0.45M of sucrose (C) or 80 µM of Dynasore (D). …”

HeLa (Cilengitide treatment or MBCD treatment) PREM membrane images supporting "The structure and spontaneous curvature of clathrin lattices at the plasma membrane" by Kem Sochacki (10280270)

“…<br><div><br></div><div>HeLa cells were treated with drugs to remove cholesterol (methyl-β-cyclodextrin) or block the binding of aVB5 integrin (Cilengitide). Removing cholesterol caused an increase in flat clathrin while blocking integrins caused a decrease in flat clathrin. …”

Real-time PCR quantifications in the presence of primers with different annealing abilities. by Michele Guescini (169183)

“…Each symbol represents a mean of 4 runs. SOD detected all the runs obtained using [ND1F5]≥250 nM as outliers.…”

MSR algorithm analysis. by Federico Comoglio (224744)

“…(B) The mean move length significantly decreases as a function of the protein length. …”

Data_Sheet_1_Impacts of Heart Failure and Physical Performance on Long-Term Mortality in Old Patients With Chronic Kidney Disease.pdf by Shuo-Chun Weng (546159)

“…Rockwood frailty and HF were both significantly associated with CKD stages. After a mean follow-up period of 3.1 ± 2.1 years, 44 patients died, and a crude analysis showed that stage 4, stage 5 CKD, low HGS, and Rockwood frailty index were associated with mortality. …”

Data_Sheet_2_Dynamic connectivity patterns of resting-state brain functional networks in healthy individuals after acute alcohol intake.xlsx by Gengbiao Zhang (11679481)

“…The fractional windows and mean dwell time of 0.5 h group and 1 h group increased in state 3, while the fraction window and mean dwell time of 1 h group decreased in state 1. …”

Data_Sheet_1_Dynamic connectivity patterns of resting-state brain functional networks in healthy individuals after acute alcohol intake.docx by Gengbiao Zhang (11679481)

“…The fractional windows and mean dwell time of 0.5 h group and 1 h group increased in state 3, while the fraction window and mean dwell time of 1 h group decreased in state 1. …”

Snail regulates RELN expression in ESCC cells. by Yi Yuan (180239)

“…<p><b>A&B</b>: Snail protein was increased (<b>A</b>) and RELN mRNA was decreased (<b>B</b>) in a time-dependent manner after 5 ng/ml TGF-β1 treatment in KYSE-510 cells. β-actin served as the loading control in Western blot. …”

Taxonomic and Functional Metagenomic Signature of Turfs in the Abrolhos Reef System (Brazil) by Juline M. Walter (3070701)

“…Their presence is associated with a reduction in three-dimensional coral reef complexity and decreases the habitats available for reef biodiversity. …”

Curcumin suppresses cell proliferation and clonogenic ability of AtT20 cells. by Madhavi Latha Yadav Bangaru (365520)

“…<p>(<i>A</i>) AtT20 cells were treated with the indicated concentrations of curcumin and cell proliferation was determined by MTT assay after 4 days. …”

Development of pH-Controlled Aluminum-Based Polymeric Gel for Conformance Control in Sour Gas Reservoirs by Shamlooh M.

“…The results reveal that aluminum acetate, among the screened salts, has a controllable gelation time at pH conditions between 3.5 and 8.5 and is the most stable in the temperature range 25–100 °C. …”
Get full text
Get full text
Get full text

Increased aerobic glycolysis in MADD fibroblasts and <i>xav</i> mutants. by Yuanquan Song (238595)

“…<p><b>A.</b> ECAR was measured in intact control and MADD Patient 1 fibroblasts under basal conditions, following the addition of the mitochondrial inhibitor oligomycin (0.5 µg/ml), in the presence of the uncoupler CICCP (3 µM) and following the addition of the complex I inhibitor rotenone (100 nM). …”

Vulnerability to high fat diet-induced obesity. by Alessandro Bartolomucci (165364)

“…At baseline, when mice were fed standard diet, all experimental groups showed a decrease in body weight, while controls (Con) showed a slight increase (F(3,23) = 3.2, p<0.05). …”

Mendelian randomization highlights the causal role of normal thyroid function on blood lipid profiles by Yanjun Wang (9719672)

Table_1_Diel Patterns of Variable Fluorescence and Carbon Fixation of Picocyanobacteria Prochlorococcus-Dominated Phytoplankton in the South China Sea Basin.docx by Yuyuan Xie (2614804)

“…We found that phytoplankton photosynthetic performance at stations SEATS and SS1 were characterized by a nocturnal decrease, dawn maximum, and midday decrease of the maximum quantum yield of PSII (Fv(′)/Fm(′), which has been denoted as both F_v/F_m and Fv′/Fm′) in the nutrient-depleted surface layer. …”

Functional connectivity revealed by rsfcMRI. by Corinna M. Bauer (3854026)