Identification of OPG147 as a conserved inhibitor of the cGAS-mediated pathway. by Xue-Mei Yi (18851202)

The chemical structure and the enzymatic and cellular activity of GSK360A. by Jin Zhou (90734)

A proposed ontogenetic series featuring <i>Delorhynchus cifellii</i> exhibiting the progressive decrease in size and division of the lateral temporal fenestrae as a result of the c... by Yara Haridy (3374018)

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... by Shuhei Ikeda (2380180)

Subjects:

RDA analysis of environmental factors and fungal community composition (A), diversity (B). by Xiaoqing Li (186909)

50 year old female with Libman-Sacks endocarditis complicated with an acute transient ischemic attack, past stroke, and seizure disorder. by Carlos A. Roldan (10151007)

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

LPS administration demonstrated a significant decrease in the protein expression of both claudin-1 and occludin in BF fed mice as compared to control mice. by Valentina Di Caro (510473)

Leptin deficit hypoxia exposed-MSCs failed to limit cardiac fibroblast activation, through TGF-β/Smad2 and MRTF-A. by Panpan Chen (307628)

Effect of MF (2 MT, 50 Hz) on VEGFR expression and activation. by Simona Delle Monache (402973)

“…<p>Protein of equal quantity was separated by 8% SDS-page and electroblotted on to a PVDF membrane. Representative blots show effects exerted by MF (2 mT, 50 Hz) on VEGFR2 total expression and phosphorylation after 1 h, 6 h and 12 h of exposure A). …”

ChemRich enrichment of the top 50 most changed metabolites for SCD. by Juliette Cooke (11402543)

A small group of plains zebra taken at a real-world equivalent of 16.4 m as they may appear to a human (a,c,e) and lion (b,d,f) under photopic (bright; daylight), mesopic (dim; dus... by Amanda D. Melin (270203)

50% reduction of kinesin-1 or dynein is sufficient to perturb neuronal growth. by Gary J. Iacobucci (192833)

“…<p>(<b>A</b>) Representative neuronal cultures expressing APP-YFP and APP-YFP with 50% genetic reduction of either kinesin-1 or dynein are shown at day 1 and day 2. …”

Table_1_Decrease in Admissions and Change in the Diagnostic Landscape in a Newborn Care Unit in Northern Ghana During the COVID-19 Pandemic.DOC by Alhassan Abdul-Mumin (5986151)

“…</p><p>Conclusion: We observed a marked decrease in admissions and change in the diagnosis landscape and related mortality during the pandemic. …”

Dependence of seizure transition times on (<i>dν</i>_<i>se</i>/<i>dt</i>)^−1/2 with the default parameters as in Table 1 and Δ ranges from 2 s to 50 s. by F. Deeba (8661837)

Neural networks classify states which differ in neuronal activity levels using ensembles of neurons that increase/decrease their activity in each state. by Nicholas A. Frost (10739821)

“…As a result, there is an increase (neurons 51:100) or decrease (neurons 1:50) in activity levels in State B compared to State A. …”

<i>Vps34</i> KO MEFs show a decrease in LC3 conjugation and LC3 puncta formation upon starvation. by Kelly Devereaux (466106)

In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin by Stephanie A. Eytcheson (4284421)

“…EPA’s ToxCast phase1_v2, phase 2, and e1k libraries for competitive binding to one of the carrier proteins, thyroxine-binding globulin. Initial screening at a single high concentration of 100 μM identified 714 chemicals that decreased signal of the bound fluorescent ligand by 20% or higher. …”