Table8_Comprehensive Analysis of the Transcriptome-Wide m6A Methylation Modification Difference in Liver Fibrosis Mice by High-Throughput m6A Sequencing.XLSX by Chang Fan (5305073)

“…In an additional cell experiment, we also observed that the decreased expression of WTAP induced the development of LF as a result of promoting hepatic stellate cell (HSC) activation. …”

Human Disturbances, Habitat Characteristics and Social Environment Generate Sex-Specific Responses in Vigilance of Mediterranean Mouflon by Stéphanie Benoist (503343)

“…Increasing group size was only found to reduce vigilance in females (up to 17.5%), not in males. We also showed sex-specific responses to habitat characteristics. …”

Dietary Fe₃O₄ Nanozymes Prevent the Injury of Neurons and Blood–Brain Barrier Integrity from Cerebral Ischemic Stroke by Bing Chun Yan (8152314)

“…<i>Ex vivo</i> analysis shows that PEG-modified Fe₃O₄ nanozymes localize in the cerebral vasculature, ameliorate local redox state with decreased malondialdehyde and increased Cu/Zn SOD, and facilitate blood–brain-barrier recovery by elevating ZO-1 and Claudin-5 in the hippocampus. …”

Early CD8⁺-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT by Juha Ranti (5774918)

“…We found that CD8⁺ T-cell counts exceeding 50x10⁶/l as early as on day 28 post-transplantation correlated significantly with decreased relapse risk, with three-year relapse rates of 17.0% and 55.6% (P = 0.002), but were also associated with severe acute and chronic GVHD. …”

BCN-Encapsulated Nano-nickel Synergistically Promotes Ambient Electrochemical Dinitrogen Reduction by Xue Zhao (76712)

“…The interaction between the BCN matrix and Ni nanoparticles promotes a synergetic effect for the electrochemical NRR efficiency due to the partial electron transfer from the Ni particles to BCN that inhibits hydrogen evolution reaction and decreases the rate-determining step on Ni surfaces toward NRR by ∼1.5 times. …”

Table_2_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.docx by Margaret Caroline Stapleton (17437713)

“…We investigated the brain network structure in adult ApoE knock out (ApoE KO) and wild-type (WT) mice with diffusion tensor imaging (DTI) followed by graph theory to delineate brain network topology. …”

Data_Sheet_1_P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo.PDF by Chao Gu (402478)

“…Furthermore, in LPS-treated microglia, P7C3-pretreatment decreased the toxicity of conditioned media to MES23.5 cells (a dopaminergic (DA) cell line). …”

DataSheet_1_Molecular identification and functional characterization of two glycosyltransferases genes from Fallopia multiflora.pdf by Qizhong Cai (14226860)

“…Further experiments on the in vivo function of FmUGT1 and FmUGT2 showed that 2, 3, 5, 4’- tetrahydroxy stilbene-2-O-β-d-glucoside (THSG) content in hairy roots was elevated significantly when FmUGT1 and FmUGT2 were overexpressed and decreased accordingly in the RNA interference (RNAi) groups. …”

Table 4_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS by Bart Nieuwenhuis (9507389)

“…To better understand this decline whilst aiming to improve regeneration, we focused on phosphoinositide 3‐kinase (PI3K) and its product phosphatidylinositol (3,4,5)‐trisphosphate (PIP3). …”

Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport by Michelle H. Le (846793)

“…To determine the functional consequences of stress-induced tau-P, we developed a novel mouse neuronal cell culture system to explore the impact of acute (0.5hr) and chronic (2hr) CRF treatment on tau-P and integral cell processes such as axon transport. …”

Data Sheet 1_Genome-wide development of SSR molecular markers for modern sugarcane cultivars.docx by Yi Xu (131145)

“…Notably, a significant positive correlation (r = 0.958) was detected between genome size and the number of SSRs. We identified SSR loci in the whole genome of XTT22, a modern sugarcane cultivar. …”

Presentation_1_The Checkpoint Regulator SLAMF3 Preferentially Prevents Expansion of Auto-Reactive B Cells Generated by Graft-vs.-Host Disease.PPTX by Ninghai Wang (709440)

“…We find that administering αSLAMF3 to NP-OVA immunized B6 mice primarily impairs antibody responses and Germinal center B cell [GC B] numbers, whilst CXCR5⁺, PD-1⁺, and ICOS⁺ T follicular helper (TFH) cells are not significantly affected. …”

DataSheet_1_Immunophenotype associated with high sustained antibody titers against enzyme replacement therapy in infantile-onset Pompe disease.pdf by Ankit K. Desai (9214082)

“…Finally, using principal components analysis, we derived an HSAT Signature Score that successfully stratified patients according to their antibody titers.…”

Table1_Prognostic Value and Therapeutic Perspectives of CXCR Members in the Glioma Microenvironment.XLSX by Jiarong He (11824972)

“…</p><p>Results: The mRNA expression levels of CXCR1/2/3/4/7 were significantly up-regulated in glioma than in normal samples, whereas the mRNA expression level of CXCR5 was decreased. We then summarized the genetic alteration landscape of CXCR and identified two molecular subtypes based on CXCR expression patterns in glioma. …”

Image_4_Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma.eps by Simon Le Gallou (10742601)

“…On the opposite, nonclassical monocytes (ncMOSlan^pos, CD14^low CD16^pos Slan^neg and ncMOSlan^neg, CD14^low CD16^pos, Slan^neg) were decreased in peripheral blood. Tumor-conditioned monocytes presented similarities with ncMO phenotype from DLBCL and were prone to migrate in response to CCL5 and CXCL12, and presented similarities with DLBCL-infiltrated myeloid cells, as defined by mass cytometry. …”

Image 4_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Image_1_Pathogenicity Traits Correlate With the Susceptible Vitis vinifera Leaf Physiology Transition in the Biotroph Fungus Erysiphe necator: An Adaptation to Plant Ontogenic Resi... by Agnes Calonnec (6066989)

“…Using leaf age, we were able to accurately predict the susceptibility of the leaf: a leaf aged, on average, 13.3 days had a very high probability (0.8) of being susceptible, while this probability decreased to 0.5 one week later. …”

Data_Sheet_1_Modeling Coral Bleaching Mitigation Potential of Water Vertical Translocation – An Analogue to Geoengineered Artificial Upwelling.docx by Ellias Y. Feng (9693842)

“…While omitting the discussion on sub-grid hydrology, we simulated in our model a water translocation from either 130 or 550 m depth to sea surface at rates of 1 or 50 m³ s^–1 as analogs to AU implementation. …”

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…The BCAA-restricted diet marginally lowered Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) levels: baseline 1.5 ± 0.2 to 1.0 ± 0.1; (p = 0.096).</p> <p>Conclusion: We successfully lowered circulating BCAAs by 50% while maintaining iso-nitrogenous, iso-caloric dietary intakes, and while meeting the recommended daily allowances (RDA) for protein requirements. …”