Table1_Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes.DOCX by Maximillian Fischer (14758063)

“…Of 43 targets screened, siRNA-mediated depletion of Fbxo6, Fbxo45, and Fbxl14 resulted in decreased cell size, whereas depletion of Fbxo9, Fbxo25, Fbxo30, Fbxo32, Fbxo33, Cullin1, Roc1, Ddb1, Fbxw4, and Fbxw5 led to a markedly increased cell size under basal conditions. …”

Table_6_Network pharmacology analysis and experimental verification reveal the mechanism of the traditional Chinese medicine YU-Pingfeng San alleviating allergic rhinitis inflammat... by Zhen Liu (74646)

“…Finally, three hub gene targeting epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), and protein kinase B1 (AKT1) related to YPFS and AR were identified by network pharmacology analysis. YPFS treatment decreased the expression of EGFR, MAPK1, and AKT1 in ovalbumin (OVA)-induced AR mice and impaired the production of inflammatory factors interleukin (IL)-4, IL-5, and IL-13, thus alleviating immunoglobulin E (IgE) production and the symptoms of scratching nose in AR. …”

Correlation of patterns in a system with the Turing mechanism. by John M. Brooke (12306638)

“…<p>We conducted a parameter sweep comparable to that presented in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009963#pcbi.1009963.g005" target="_blank">Fig 5</a>, instead using the Schnackenberg reaction-diffusion system [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009963#pcbi.1009963.ref022" target="_blank">22</a>], whereby patterns form via the Turing mechanism. …”

Table_1_Network pharmacology analysis and experimental verification reveal the mechanism of the traditional Chinese medicine YU-Pingfeng San alleviating allergic rhinitis inflammat... by Zhen Liu (74646)

“…Finally, three hub gene targeting epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), and protein kinase B1 (AKT1) related to YPFS and AR were identified by network pharmacology analysis. YPFS treatment decreased the expression of EGFR, MAPK1, and AKT1 in ovalbumin (OVA)-induced AR mice and impaired the production of inflammatory factors interleukin (IL)-4, IL-5, and IL-13, thus alleviating immunoglobulin E (IgE) production and the symptoms of scratching nose in AR. …”

Image_1_Striate Artery Infarct After Bilateral Carotid Artery Ligation (BCAL) in a Dog: A Multimodal MRI Study.TIFF by Lukas Komornik (9394952)

“…Collateral blood supply can develop as early as 5 days after surgery.</p>…”

Syntheses and X-ray Diffraction Studies of Half-Sandwich Hydridosilyl Complexes of Ruthenium by Alexander L. Osipov (2693335)

“…NMR reaction between Cp*(MePrⁱ₂P)Ru(H)₃ and excess Cl₃SiMe at 100 °C resulted in a clean formation of Cp*(MePrⁱ₂P)Ru(H)(Cl)(SiCl₂Me). …”

Responses of the pub44 and pub43 T–DNA lines to various stresses treatments during germination. by Jennifer N. Salt (215876)

“…A 1∶1 ratio of wild-type and <i>PUB44/pub44</i> seedlings were observed in the germinated seedlings displaying decreased sensitivity to ABA [n =  100 47∶53; χ² =  0.36, P<0.05]. …”

Analysis of hibernation-state dependent alternative splicing of tau exon 10 in arctic ground squirrels (<i>Spermophilus parryii</i>) (euthermic n = 4; torpor long n = 4, arousal lo... by Jens T. Stieler (232780)

“…The expression was calculated as percentage related to the summative intensity of all bands (set to 100 %). The tau isoform expression pattern is significantly altered during hibernation (p = 0.0043; ANOVA) and the expression of tau isoforms including exon 10 is significantly decreased in the state of torpor (p = 0.0081; t-Test) and after arousal (p = 0.002; t-Test).…”

Diagram of the electrical stimulator for small animals and results of preliminary experiments to determine the stimulation intensity and time. by Yuichiro Honda (10797856)

“…<p>(A) The control unit sets the duty cycle, frequency, and intensity. …”

Internal and external modes in mouse perceptual decision-making. by Veith Weilnhammer (2909060)

“…(<b>B</b>) Relative to randomly permuted data, we found highly significant autocorrelations of stimulus-congruence and history-congruence (dots indicate intercepts ≠ 0 in trial-wise linear mixed effects modeling at <i>p</i> < 0.05). …”

Wdr24 promotes TORC1 activity and cell growth in both germline and somatic cells. by Weili Cai (365746)

“…The <i>wdr24</i>^<i>1</i> mutant cells are marked by the absence of GFP and are outlined by a red line. Note that <i>wdr24</i>^<i>1</i> mutant cells have a smaller nuclear size suggesting decreased ploidy. …”

SLMO is required for the proper function of PISD. by Siwen Zhao (543384)

“…<i>w</i>^<i>1118</i> was used as a wild-type control. The scale bar is 100 μm. (D) Light microscope images of eyes of 1-day-old <i>w</i>^<i>1118</i> and <i>slmo</i>^<i>1</i> (<i>ey-flp;slmo</i>^<i>1</i> <i>FRT40A/GMR-hid CL FRT40A</i>) flies. …”

Data_Sheet_1_Investigating the relationship between non-occupational pesticide exposure and metabolomic biomarkers.docx by Saranya Palaniswamy (11854188)

“…OPE, PEY, and PEU were associated with decreased branched-chain amino acid concentrations in men and decreased albumin concentrations in women. …”

PF-04991532 increased hepatic futile cycling. by Derek M. Erion (568011)

“…<p>The effect of hepatic glucokinase activation on G6Pase (<b>A</b>) and the loss of positional labeling (<b>B</b>) in primary rat hepatocytes. …”

Expression of Bcl-2, Bax, Survivin, ERK, cytochrome C, Caspase-3 and VEGF in 4T1 cells after 48 h treatment of fucoidan detected by Western blot. by Meilan Xue (310911)

“…Fucoidan decreased VEGF expression in 4T1 cells. Lane 1: control cells; lanes 2–4: 4T1 cells treated with 50, 100 and 200 μg/ml fucoidan respectively. …”

Markers exhibiting differential levels of staining between CADASIL and control arteries or between leptomeninges and white matter. by Soo Jung Lee (8313594)

“…A) Immunohistochemical examination of markers (labels to the left) which had decreased staining in CADASIL relative to controls. …”

Reduced liver fibrosis in <i>CCL3^−/−</i> mice after CCl₄ challenge. by Daniel Heinrichs (323862)

“…<p>Acute liver injury after CCl₄ challenge is associated with augmented hepatic expression of CCL3, while CCL3 after chronic CCl₄ treatment has a tendency toward higher expression (<b>A</b>). …”

Light Microscopic Analysis of Other Hippocampal Regions. by Hiroaki Nabeka (485031)

“…PS18 treatment following a KA injection in rats decreased the number of injured neurons (E, K, Q) and increased the number of viable neurons (F, L, R) in a dose-dependent manner compared with PBS-treated KA-injected rats. …”

LRRC6 expression in ciliated airway epithelial cells. by Amjad Horani (391903)

“…<p>Photomicrographs of normal human lung section (<b>A</b>) (scale bar = 100 µm) and bronchial epithelium (<b>B</b>) following immunofluorescent staining for LRRC6, which reveals the cytoplasmic localization of the protein (LRRC6, red) only in ciliated cells (acetylated α-tubulin, a cilia marker, green; DAPI: blue) (scale bar = 10 µm). …”

Astrocyte activation by GA was sufficient to induce neuronal death through soluble factors. by Silvia Olivera-Bravo (349736)

“…Neuronal number increased when treated with CM-C (first column of the chart). Conversely a concentration dependent neuronal loss was caused by CM-GA when compared with vehicle (taken as 100%, dotted line). *: p<0.05. …”