Indices of tertiary industry activity (base year is 2015 and is set at 100) and the monthly number of newly confirmed COVID-19 cases. by Kenji Hibiya (96281)

Mean GC during 10 minutes after introducing the spheroid to the medium over 8 replicates of the 100 and 75 <i>μ</i>L incubations. by Hamidreza Arjmandi (19657263)

DataSheet_1_microRNA-144/451 decreases dendritic cell bioactivity via targeting interferon-regulatory factor 5 to limit DSS-induced colitis.pdf by Zhijie Lin (173992)

“…Mechanistically, the miR-144 directly targets the 3`-UTR of IRF5 and represses the expression of IRF5 in DCs. …”

Image_3_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_4_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Biopsy. by Julia María Cabo del Riego (21703071)

“…Increasing CD incidence was observed from 13.11 per 100.000 person/year in 2012 to 20.92 per 100.000 100.000 person/year in 2019 (95% CI = 6.8–15.5). …”

CD diagnosis method. by Julia María Cabo del Riego (21703071)

“…Increasing CD incidence was observed from 13.11 per 100.000 person/year in 2012 to 20.92 per 100.000 100.000 person/year in 2019 (95% CI = 6.8–15.5). …”

Data Sheet 1_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.pdf by Arishabhas Tantibhadrasapa (13929639)

“…However, the antibacterial and immune modulatory effects of AC5 on UPEC have never been explored.</p>Methods<p>Here, we investigated both the direct and indirect effects of AC5 against UPEC isolates (UTI89, CFT073, and clinical MDR UPEC AT31) in vitro. …”

Tyro 3 overexpression decreases the production of Aβ from 293APPswe cells and Gas6 inhibits the effect in a concentration-dependent manner. by Yan Zheng (61178)

“…<p>(A, B) ELISA assay shows that the levels of (A) Aβ42 and (B) Aβ40 are significantly reduced in Tyro 3-CFP transfected cells relative to GFP transfected cells and the effect is inhibited by addition of Gas6 at the final concentration of 100 ng/ml. …”

Table_1_S100B chaperone multimers suppress the formation of oligomers during Aβ42 aggregation.XLSX by António J. Figueira (14819254)

“…We also determined that sub-molar ratios of tetrameric apo-S100B decrease Aβ42 oligomerization influx down to 10%, while precluding both secondary nucleation and, more discreetly, fibril elongation. …”

The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”

Table_5_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Fig 2 - by Chung-Fen Tsai (3175947)

Age-adjusted suicide rates per 100,000 in each occupation, Japan, 1975–2005^a. by Etsuji Suzuki (113381)

Decreased endothelial function in a subfailure overstretch RA model was restored with apyrase and P2X7R antagonists FCF and A740003. by Padmini Komalavilas (402160)

Body size of saproxylic beetles on a south-facing slope (SFS) and a north-facing slope (NFS). by Jörn Buse (750216)

Spatial arrangement for vergence (A): three LEDS aligned along the median plane of the subject: at 20, 40 and 100 cm. by Zoï Kapoula (3181413)

“…The target LED could be either at 20 cm (requiring an increase of convergence angle from 8.6° to of 17.1°, or at 100 cm, requiring a decrease of convergence angle from 8.6° to 3.4°, i.e. a divergence movement)</p>…”

Dexmedetomidine in combination with morphine improves postoperative analgesia and sleep quality in elderly patients after open abdominal surgery: A pilot randomized control trial by Huai-Jin Li (5628722)

“…</p><p>Methods</p><p>This was a pilot randomized controlled trial. 58 elderly patients (age ≥ 60 years) who underwent open abdominal surgery were randomized to receive either dexmedetomidine supplemented morphine analgesia (0.5 mg/ml morphine plus 2 μg/ml dexmedetomidine in 100 ml normal saline, DEX group) or morphine analgesia (0.5 mg/ml morphine in 100 ml normal saline, CTRL group) for 72 hours after surgery. …”