Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

ATG 5 down-regulation decreases human A53T ASYN-induced death in rat cortical neurons. by Maria Xilouri (264240)

EphA4 immunostaining is decreased adjacent to injury site in ephrin-A5-Fc treated mice. by Yona Goldshmit (205708)

“…Arrows indicate lesion site. Scale bars in A–D, G,H, 100 µm; E,F, 50 µm.</p>…”

BKM120 decreases cellular glycolytic metabolic activity in MB cell lines. by Ping Zhao (47228)

EQI decreases malonyl-CoA levels in <i>S</i>. <i>aureus</i>. by Erica C. Larson (1344687)

S5 Fig - by Xinyue Yang (629144)

“…On day 8, the rats were transferred to a simulated climate cabin, At 0, 50, 100, and 150 min, the core temperature (Tc) was measured respectively. …”

SrpR binds the centromere-like region <i>srpC</i>. by Nicolas Carraro (650366)

Pharmacological inhibition and/or siRNA silencing of EP2 receptor in EP2S cells decrease claudin-4 expression. by Manigandan Lejeune (458492)

Mental health group common bigram words (Top 50) before and after pandemic. by Yuxuan Cai (19226202)

50 WT 5′ and 3′ terminal nts of the S1 gene are sufficient to package a non-MRV gene into infectious virions. by Debarpan Dhar (724473)

Image_5_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOT... by Yung-Yu Yang (9343376)

“…In both the normal and diseased HBE cells, intermittent H/R significantly increased HIF1A, BMP4, NOTCH1, MKI67, OCT4, and MUC5AC expression, while consecutive hypoxia significantly decreased NKX2-1, NOTCH3, HEY1, CC10, and FOXJ1 expression. …”

<i>Vps13</i> mutant flies show a decreased life span, age dependent impairment of locomotor function and neurodegeneration. by Jan J. Vonk (3686662)

The Impact of Prophylactic Dexamethasone on Nausea and Vomiting after Thyroidectomy: A Systematic Review and Meta-Analysis by Zhenhong Zou (645858)

“…The meta-analysis demonstrated a significant decrease in the incidence of PONV (RR 0.52, 95% CI 0.43 to 0.63, <i>P</i><0.00001), the need for rescue anti-emetics (RR 0.42, 95% CI 0.30 to 0.57, <i>P</i><0.00001), post-operative pain scores (WMD –1.17, 95% CI –1.91 to –0.44, <i>P</i> = 0.002), and the need for rescue analgesics (RR 0.65, 95% CI 0.50–0.83, <i>P</i> = 0.0008) in patients receiving dexamethasone compared to placebo, with or without concomitant antiemetics. …”

Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

“…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC₅₀’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …”

Titanate Nanosheets/Cellulose Composite Showing Improved Crystallinity and Decreased Water Wettability by Gamma-Irradiation by Yaowaluk Tariwong (22630109)

Activation of Wnt/β-catenin signaling decreases mRNA expressions of <i>Scx</i>, <i>Mkx</i> and <i>Tnmd</i> in rat TDCs. by Yasuzumi Kishimoto (4282138)

“…<p>Relative expressions of <i>Axin2</i>, <i>Scx</i>, <i>Mkx</i>, and <i>Tnmd</i> in TDCs treated with 50 ng/ml Wnt3a with or without 5 μM IWR (an inhibitor of β-catenin) <b>(A)</b>, 0 to 4 μM BIO (an activator of β-catenin) <b>(B)</b>, or 0 to 20 μM IWR <b>(C)</b> for 72 hrs. …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”

Chloro Half-Sandwich Osmium(II) Complexes:  Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity by Anna F. A. Peacock (1297842)

“…The rates of hydrolysis at acidic pH* decreased when the primary amine N-donors (NN = en, <i>t</i>_1/2 = 0.6 h at 318 K) are replaced with π-accepting pyridine groups (e.g., NN = phen, <i>t</i>_1/2 = 9.5 h at 318 K). …”