RNA Environment Is Responsible for Decreased Photostability of Uracil by Sebastian Reiter (5496599)

RNA Environment Is Responsible for Decreased Photostability of Uracil by Sebastian Reiter (5496599)

RNA Environment Is Responsible for Decreased Photostability of Uracil by Sebastian Reiter (5496599)

RNA Environment Is Responsible for Decreased Photostability of Uracil by Sebastian Reiter (5496599)

RNA Environment Is Responsible for Decreased Photostability of Uracil by Sebastian Reiter (5496599)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

High glucose induces a mild decrease in KIF5B but does not affect the overall content and distribution of tau, KIF1A and dynein in hippocampal cultures. by Filipa I. Baptista (145150)

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia by Xiaofeng Wang (119575)

“…Furthermore, we found that FGFR3 interacted with ATG12–ATG5 conjugate by binding to ATG5. …”

Data_Sheet_5_Chronic Neurobehavioral Impairments and Decreased Hippocampal Expression of Genes Important for Brain Glucose Utilization in a Mouse Model of Mild TBI.xlsx by Linda M. Huynh (9395591)

Experimental outline. by Melissa A. MacIver (12850566)

Infection with <i>Shigella flexneri</i> M90T<i>ΔaroA</i> results in a decrease in TAMs number. by Katharina Galmbacher (252251)

As the number of infections <i>I</i> in a given county increases, the variance in exponential growth rate, Var(Δ<i>I</i>/<i>I</i>), decreases as . by Calvin Pozderac (10451496)

<i>WDR5</i> Expression Is Prognostic of Breast Cancer Outcome by Xiaofeng Dai (793874)

“…Given the similarities between breast and prostate cancers, we explore the potential prognostic value of <i>WDR5</i> gene expression on breast cancer survival. …”

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. by Jian Zhang (1682)

ST2-104 decreases the Aβ_25-35-mediated increase in intracellular Ca²⁺. by Yingshi Ji (9013004)

Stress strain curves (from a1 to f1), stress—AE count plots (from a2 to f2) and stress—cumulative AE count plots (from a3 to f3) for the sample temperatures of 20°C, 50°C, 100°C, 1... by Nazlı Tunar Özcan (14833635)

Can We Disrupt the Sensing of Honey Bees by the Bee Parasite <i>Varroa destructor</i>? by Nurit Eliash (630195)

“…In particular, we examined the effect of volatile compounds, ethers of <i>cis</i> 5-(2′-hydroxyethyl) cyclopent-2-en-1-ol or of dihydroquinone, resorcinol or catechol. …”

A decreased yield of RNP1, RNP2 and RNP5 formation in the presence of protein aGAR1 is counteracted by RNA-S by Bruno Charpentier (9519)

Nucleotide sequence changes in E6, L1 (MY), and LCR regions from A1/2, D2 and D3 HPV16 variants. by Ana Alfaro (280118)