Supplementary file 1_Effectiveness of digital pain management for older adults with musculoskeletal pain: systematic review with meta-analysis.docx by Anabela G. Silva (8460759)

“…Introduction<p>Musculoskeletal pain is highly prevalent among older adults and a leading cause of disability. Digital health promises to deliver timely and quality care, but existing reviews fail to be specific for older adults, focus on a single type of technology or a single body site, and do not provide an integrated overview of the effectiveness of current digital interventions. …”

Leptin alone and in combination with interleukin-1-beta induced cartilage degradation potentially inhibited by EPA and DHA by Thanyaluck Phitak (4518742)

“…Interestingly, both EPA and DHA could inhibit cartilage damage induced by leptin plus IL1β by reducing the activation of NFκB and JNK, which led to the decrease of ADAMTS4 secretion. Altogether, only a supra-pathological concentration of leptin alone or in combination with IL1β could induce cartilage destruction, whereas a pathological one could not. …”

Bunched, the homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth-2 by Silvia Gluderer (70476)

“…The effect on clone area is slightly more pronounced than the effect on cell number, indicating a decrease in size of mutant cells. (F) The average area of the mutant cells is 5% () and 10% () smaller than the average area of the wild-type sister cells.…”

Data_Sheet_1_High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens.docx by Jason Yuen (4870732)

“…VTA HFS alone decreased NAcc tonic dopamine levels by 42%. NAcc HFS alone resulted in an initial decrease in tonic dopamine levels followed by a return to baseline. …”

DataSheet_2_Bidirectional Mendelian randomization study of insulin-related traits and risk of ovarian cancer.csv by Xinghao Wang (802907)

“…</p>Results<p>Among all insulin related indicators (fasting insulin level, insulin secretion rate, peak insulin response), the insulin secretion rate was selected to have a causal relationship with the occurrence of ovarian cancer (IVW, P < 0.05), that is, the risk of ovarian cancer increased with the decrease of insulin secretion rate. …”

<i>Rfx4</i>^-/- embryos at E12.5 and E14.5 exhibit holoprosencephaly. by Ping Xu (122619)

“…<p>Note the complete absence of the developing cerebral hemispheres (CH) in the KO embryo seen in A-C. There was a striking decrease in size of all regions of the brain, but especially the developing midbrain in (D). …”

Table 2_Dose-optimized microbial inoculants reshape grape rhizosphere microbiota and enhance fruit quality.xlsx by Xiaojian Chang (738291)

“…</p>Results<p>The results indicated that inoculant application significantly increased the relative abundance of bacterial phyla Proteobacteria and Actinobacteria, along with the genera Bacillus, Nitrospira, and Pseudomonas. Concurrently, a decrease in the relative abundance of fungi from the phylum Ascomycota (e.g., Penicillium, Fusarium) was observed, whereas an increase was noted for phyla Mortierellomycota and Basidiomycota, and genera such as Mortierella and Solicoccozyma. …”

Table_1_Assessment of the changes in seed yield and nutritional quality of quinoa grown under rainfed Mediterranean environments.docx by Javier Matías (10785522)

“…Furthermore, nutritional and metabolomic differences were observed among seeds harvested from different water environments including the progressive accumulation of glycine betaine accompanied by an increase in saponin and a decrease in iron with water limitation. Generally, water-limiting environments were associated with increased protein contents and decreased yields preserving a high nutritional quality despite particular changes. …”

Atypical E2f functions are critical for pancreas polyploidization by Ramadhan B. Matondo (4763097)

“…However, deficiency of <i>E2f7</i> or <i>E2f8</i> alone was sufficient to suppress polyploidization in the pancreas and associated with only a minor decrease in blood serum levels of glucose, insulin, amylase and lipase under 4 hours starvation condition compared to wildtype littermates. …”

Molecular Structures, Dipole Moments, and Electronic Properties of β‑HMX under External Electric Field from First-Principles Calculations by Yu-Shi Liu (6647582)

“…When the external electric field is increasing along the [100], [010], and [001] crystallographic directions of β-HMX, the calculation results indicate that an increase in the bond length (N1–N3/N1′–N3′) of the triggering bond, an increase in the main <i>Q</i>_nitro (N3, N3′) value, an increase in the minimum surface electrostatic potential, and a decrease in band gap all contribute to a reduction in its stability. …”

Image_4_Repetitive Pain in Neonatal Male Rats Impairs Hippocampus-Dependent Fear Memory Later in Life.tif by Dongqing Xia (4334530)

“…Moreover, repetitive neonatal procedural pain caused a significant decrease in the magnitude of hippocampal long-term potentiation induced by high-frequency stimulation. …”

Amplex Red H₂O₂ measurements in <i>E</i>. <i>faecalis</i>-fed worms. by Saida Benomar (561001)

“…<p>(A) PBO-1, but not PBO-4, is important for H₂O₂ production in response to <i>E</i>. …”

Scheme representation of metabolic abnormalities in the absence of PrP^C. by Hélène Arnould (3165201)

“…This provokes a decrease of the glycolytic flux in favor of an increase in the fatty acids β-oxidation rate, which combined to the excess of synthesized ATP sustain high PDK4 activity. …”

The–log p-value graphs for LOO-V analysis for each significant window for <i>BRCA2</i>, <i>BRCA1</i>, <i>SMG1</i>. by Cavin Wong (7330154)

“…<p>A decrease in the–log p-value corresponds to an increase in p-value, signifying the dropped variant is potentially driving the association with PC risk. …”

The acute exposure effects of inhaled nickel nanoparticles on murine endothelial progenitor cells by Eric N. Liberda (502920)

“…These results coincided with a decrease in the mRNA of receptors involved in EPC mobilization and homing. …”

Data Sheet 1_Multi-scenario assessment of landscape ecological risk in the transitional zone between the warm temperate zone and the northern subtropical zone.pdf by Chenghang Li (14266791)

“…The findings have provided a scientific reference for the ecological and environmental management of areas with intense human activity under complex climatic conditions.…”

New Lanthanide Hybrid as Clustered Infinite Nanotunnel with 3D Ln−O−Ln Framework and (3,4)-Connected Net by You-gui Huang (1712638)

“…Variable-temperature magnetic susceptibility measurements of <b>1</b>−<b>6</b> showed that the complexes <b>1</b>−<b>3</b> are nearly paramagnets, whereas the depopulation of the Stark levels in complexes <b>4</b>−<b>6</b> leads to a continuous decrease in μ_eff when the sample is cooled from 300 to 2 K.…”

Data Sheet 1_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf S... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. …”

Image_3_Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea.jpeg by Andrea Pagano (7845914)

“…</p>Results and discussion<p>After 3 weeks of recovery from zebularine treatment, a decrease of 5-mC levels was observed in different genomic contexts in the roots of explants that were exposed to zebularine, whereas a functionally heterogeneous subset of protein entries was differentially accumulated in stem samples, including entries related to cell wall biosynthesis, tissue morphogenesis, and hormonal regulation. …”

New Lanthanide Hybrid as Clustered Infinite Nanotunnel with 3D Ln−O−Ln Framework and (3,4)-Connected Net by You-gui Huang (1712638)

“…Variable-temperature magnetic susceptibility measurements of <b>1</b>−<b>6</b> showed that the complexes <b>1</b>−<b>3</b> are nearly paramagnets, whereas the depopulation of the Stark levels in complexes <b>4</b>−<b>6</b> leads to a continuous decrease in μ_eff when the sample is cooled from 300 to 2 K.…”