sup fig4 by Qian Zhang (9085316)

“…<b> </b>a, P<0.05 vs VDR-shRNA plasmid. Mean gray value=Integrated Density/Area.…”

Effects of Gpnmb expression on hepatic macrophages. by Kotaro Kumagai (496421)

“…Moreover, (B) mRNA expression of TGF-β and MMP-13 is not affected by inhibited Gpnmb expression, however secretion of MMP-13, but not TGF-β is significantly decreased by inhibition of Gpnmb expression. Values are mean ± SEM (<i>n</i> = 3). * <i>P</i> < 0.05 vs. control (Tukey’s HSD test).…”

Increasing Notch1 activity in MAFs suppresses tumor angiogenesis. by Hongwei Shao (493627)

“…<i>Top</i>: representative images; <i>Bottom</i>: relative blood vessel density calculated as % of red pixel in total area examined by confocal microscopy. Data are mean ± SD, n = 5 tumors/group. <b>B.</b> Significantly decreased blood vessel density is observed in 1205Lu co-grafted with N1^IC-GFP/MAF. …”

20-HETE increases murine airway sensitivity to carbachol. by Philip R. Cooper (188104)

“…<p>Lung slices from naïve mice were incubated over-night with 20-HETE (10 and 1 ng/mL). (A) Airways were contracted to carbachol (CCh) to create concentration-response curves. …”

Ca²⁺ flux assay in Y511F and S512 mutants for capsaicin and [6]-gingerol. by Katsuya Ohbuchi (559460)

“…<p>(A) The potency of capsaicin against TRPV1 was decreased a little for Y511F (red) but unchanged for S512A (blue). …”

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway by Chakrabhavi Dhananjaya Mohan (773464)

“…Herein, we report the synthesis of trisubstituted-imidazoles and identified 2-chloro-3-(4, 5-diphenyl-1H-imidazol-2-yl) pyridine (CIP) as lead cytotoxic agent. …”

Genetic controls shows that adaptation in LMC output is dampened by reducing L2-R feedback. by Anton Nikolaev (267464)

“…</i> change in LMC output (gray circles) is defined as the mean of the standard deviations of consecutive response segments to a second long naturalistic stimulus (NS) pattern, from the 2^nd to 20^th s (dotted box, each data point is calculated from 800-ms data sections as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004306#pone-0004306-g002" target="_blank">Fig. 2</a>). …”

Zn_<i>x</i>Mn_1–<i>X</i>Fe₂O₄@SiO₂:<i>z</i>Nd³⁺ Core–Shell Nanoparticles for Low-Field Magnetic Hyperthermia and Enh... by Marcus Vinícius-Araújo (10096489)

“…Multifunctional magnetic nanoparticles (NPs) that can generate and monitor heat (in real-time) during thermal therapy are a major challenge in nanomedicine. Here, we report a trimodal system combining magnetic NP hyperthermia (MNH), photothermal therapy (PTT), and luminescent nanothermometry (LNT) properties with an all-in-one nanoplatform. …”

Zn_<i>x</i>Mn_1–<i>X</i>Fe₂O₄@SiO₂:<i>z</i>Nd³⁺ Core–Shell Nanoparticles for Low-Field Magnetic Hyperthermia and Enh... by Marcus Vinícius-Araújo (10096489)

“…Multifunctional magnetic nanoparticles (NPs) that can generate and monitor heat (in real-time) during thermal therapy are a major challenge in nanomedicine. Here, we report a trimodal system combining magnetic NP hyperthermia (MNH), photothermal therapy (PTT), and luminescent nanothermometry (LNT) properties with an all-in-one nanoplatform. …”

Zn_<i>x</i>Mn_1–<i>X</i>Fe₂O₄@SiO₂:<i>z</i>Nd³⁺ Core–Shell Nanoparticles for Low-Field Magnetic Hyperthermia and Enh... by Marcus Vinícius-Araújo (10096489)

“…Multifunctional magnetic nanoparticles (NPs) that can generate and monitor heat (in real-time) during thermal therapy are a major challenge in nanomedicine. Here, we report a trimodal system combining magnetic NP hyperthermia (MNH), photothermal therapy (PTT), and luminescent nanothermometry (LNT) properties with an all-in-one nanoplatform. …”

Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway by Bin Wang (30851)

“…</p> <p><b>Abbreviations:</b> 3-MA: 3-methyladenine; 4-PBA: 4-phenylbutyrate; ACTB: β-actin; ATF: activating transcription factor; ATG: autophagy-related; BafA1: bafilomycin A₁; BDBV: <i>Bundibugyo</i> ebolavirus; CALR: calreticulin; CANX: calnexin; CHX: cycloheximide; CMA: chaperone-mediated autophagy; ConA: concanamycin A; CRISPR: clusters of regularly interspaced short palindromic repeats; Cas9: CRISPR-associated protein 9; dsRNA: double-stranded RNA; EBOV: <i>Zaire</i> ebolavirus; EDEM: ER degradation enhancing alpha-mannosidase like protein; EIF2AK3/PERK: eukaryotic translation initiation factor 2 alpha kinase 3; Env: envelope glycoprotein; ER: endoplasmic reticulum; ERAD: ER-associated protein degradation; ERN1/IRE1: endoplasmic reticulum to nucleus signaling 1; GP: glycoprotein; HA: hemagglutinin; HDAC6: histone deacetylase 6; HMM: high-molecular-mass; HIV-1: human immunodeficiency virus type 1; HSPA5/BiP: heat shock protein family A (Hsp70) member 5; IAV: influenza A virus; IP: immunoprecipitation; KIF: kifenesine; Lac: lactacystin; LAMP: lysosomal associated membrane protein; MAN1B1/ERManI: mannosidase alpha class 1B member 1; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MARV: Marburg virus; MLD: mucin-like domain; NHK/SERPINA1: alpha1-antitrypsin variant null (Hong Kong); NTZ: nitazoxanide; PDI: protein disulfide isomerase; RAVV: Ravn virus; RESTV: Reston ebolavirus; SARS-CoV: severe acute respiratory syndrome coronavirus; SBOV: <i>Sudan</i> ebolavirus; sGP: soluble GP; SQSTM1/p62: sequestosome 1; ssGP: small soluble GP; TAFV: Taï Forest ebolavirus; TIZ: tizoxanide; TGN: thapsigargin; TLD: TXN (thioredoxin)-like domain; Ub: ubiquitin; UPR: unfolded protein response; VLP: virus-like particle; VSV: vesicular stomatitis virus; WB: Western blotting; WT: wild-type; XBP1: X-box binding protein 1.…”

The wound healing microenvironment prevented lung cell malignant transformation. by Linxin Liu (829738)

“…(B) The combination of three compounds decreased A549 cell self-renew shown as the number of tumor spheres and soft agar colonies. …”

RG- SHAIB SHABIR (20MCT0035).pdf by SHAIB SHABIR (10644029)

“…Adulteration in food has been a concern since the beginning of civilization, as it not only decreases the quality of food products but also results in a number of ill effects on health. …”

Impacts of the FLEGT action plan and the EU timber regulation on EU trade in timber product by Paul Rougieux (9633353)

“…The shock model analysis indicates, for most of the bilateral trade flows where we observe cointegration and a significant shock variable, increasing import prices and decreasing import quantities of tropical hardwood lumber following the EUTR start date, consistent with a contraction of the supply of tropical timber. …”

Szekely2017PLoS_LongevityDatabase.sav by Anna Szekely (3369881)

“…In the present study we demonstrate the same association using continuous age groups in an 18-97 years old Caucasian sample (N=1801, p=0.007). We found a continuous pattern of increase from 18-75, however frequency of allele 7 carriers decreased in our oldest age groups. …”

Prophylactic effect of SFN on PCP-induced alterations in 8-oxo-dG immunostaining and PV-positive immunostaining in the brain. by Yumi Shirai (759726)

“…Pretreatment with SFN significantly attenuated PCP-induced increases of 8-oxo-dG immunostaining in the mPFC and CA1. The data show the mean ± SEM (n = 6 or 7). (C): Repeated PCP administration significantly decreased PV-positive immunostaining in the mPFC and CA1, but not CA3 and DG. …”

Myco+ exosome treatment inhibits anti-CD3-stimulated ERK phosphorylation. by Chenjie Yang (167929)

“…(B) Relative expression of pERK normalized to total ERK. Data represents the mean ± SD of three independent experiments. 10 µg/ml of B16 myco+ exosome treatment significantly decreased pERK/ERK compared with non treatment. …”

Data_Sheet_2_Integrating fractional amplitude of low-frequency fluctuation and functional connectivity to investigate the mechanism and prognosis of severe traumatic brain injury.D... by Biao Li (36684)

“…The parameters of these alterations can be used for predicting the long-term outcomes of patients with sTBI, of which the fALFF increase in the temporal lobe, occipital lobe, precuneus, and middle temporal gyrus showed the highest predictive ability (AUC = 0.883).</p>Conclusion<p>We provide a compensatory mechanism that several regions of the brain can be spontaneously activated at the acute phase of sTBI in those who present with a good prognosis in the 6-month follow-up, that is, a destructive mode that increases its fALFF in the local regions and weakens its FC to the whole brain. …”

Rational Molecular Engineering via Electron Reconfiguration toward Robust Dual-Electrode/Electrolyte Interphases for High-Performance Lithium Metal Batteries by Yiming Zhang (444592)

“…The strong electron-withdrawing nitrate moiety decreases the electron cloud density of the ether-based backbone, improving the overall oxidation stability and cathode compatibility, anchoring it as a reliable cathode/electrolyte interface (CEI) framework for cathode integrity. …”

Data_Sheet_3_Integrating fractional amplitude of low-frequency fluctuation and functional connectivity to investigate the mechanism and prognosis of severe traumatic brain injury.D... by Biao Li (36684)

“…The parameters of these alterations can be used for predicting the long-term outcomes of patients with sTBI, of which the fALFF increase in the temporal lobe, occipital lobe, precuneus, and middle temporal gyrus showed the highest predictive ability (AUC = 0.883).</p>Conclusion<p>We provide a compensatory mechanism that several regions of the brain can be spontaneously activated at the acute phase of sTBI in those who present with a good prognosis in the 6-month follow-up, that is, a destructive mode that increases its fALFF in the local regions and weakens its FC to the whole brain. …”