Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Vitamin D3, but not the Cisplatin, could moderately reduce STZ-induced hyperglycemia in mice (a) Schematic representation of experimental protocol followed in the study: After accl... by Vidya G. Bettada (22208808)

“…<p>The control non-diabetic group was administered with the vehicle used for dissolving the STZ, i.e., 100mM sodium citrate buffer, pH 4.5. …”

Analysis of the ¹H–¹⁵N HSQC spectrum of the labeled RAGE V domain with unlabeled S100A12. by Jian Wei Chiou (3106578)

“…<p>(a) Overlay of the ¹H–¹⁵N HSQC spectra of 0.5 mM ¹⁵N-labeled RAGE V domain (red) and the spectra of the complex with 0.5 mM unlabeled S100A12 (blue). …”

VH14PEST decreases the toxicity of α-Syn as measured by a proteostatic assay with mhttex1-72QGFP. by David C. Butler (261919)

Analysis of the ¹H–¹⁵N HSQC spectra of S100A12 in complex with the unlabeled RAGE V domain. by Jian Wei Chiou (3106578)

“…<p>(a) Overlay of the ¹H–¹⁵N HSQC spectra of 0.76 mM ¹⁵N-labeled S100A12 (red) and S100A12 in complex with 0.76 mM unlabeled RAGE V domain (green). …”

Non-Steady-State Fickian Diffusion Models Decrease the Estimated Gel Layer Diffusion Coefficient Uncertainty for Diffusive Gradients in Thin-Films Passive Samplers by Samuel D. Hodges (16412358)

“…A finite difference model (FDM) developed based on Fick’s second law with non-steady-state (N-SS) flux decreased uncertainty in <i>D</i>_Gel tenfold. …”

Autophagy inhibition decrease LAMP2 levels and survival of neuroendocrine differentiated LNCaP cells. by Cecilia Morell (729630)

Chimera and wild-type virus replication at early time points. by Anja vom Hemdt (19787189)

Top 5 VADER words by TF-IDF before, during, and after Hurricane Dorian for each region. by Krishna Bathina (12883820)

Top 5 VADER words by normalized TF-IDF scores before, during, and after each hurricane. by Krishna Bathina (12883820)

nanoDSF apparent melting points. by Aleksi Sutinen (10039145)

Fig 5 - by Melissa K. Peckins (12042132)

Univariate and multivariate predictors of sudden cardiac death or sudden cardiac arrest, non-sudden cardiac death and non-cardiac death. by Antti O. Vuoti (11068190)

Combination treatment of PLA-695 with irradiation decreases vascularity. by Dinesh Thotala (435314)

The NK1-receptor antagonist ezlopitant significantly decreases voluntary intake of non-caloric saccharin solution. by Pia Steensland (362091)

“…<p>Ezlopitant (5 and 10 mg/kg) significantly decreased consumption of the non-caloric 0.2% saccharin solution compared to vehicle. …”

Impact of PG receptor agonists on the expression of <i>S100A8/A9</i> in response to LPS. by Mohamad Karaky (8910497)

Subjects:

Influence of point mutations on proton sensitivity. by Katsuya Ohbuchi (559460)

“…Although 12 cells were evaluated in the same experiment, the results are divided into two graphs for clarity. 50 μL of D-PBS (pH 5.5) solution was added to 100μL of cells in D-PBS (pH 7.4) solution at the 20-s time point. …”

Effects of S100A6 on CayBP/SIP-mediated β –catenin degradation. by Xiaoxuan Ning (334218)

“…<p>(A) Co-immunoprecipitation assay showed that truncated mutant CacyBP/SIPΔS100 bind both Skp1 and Siah1, suggesting S100A6 did not affect the formation of Siah1-CacyBP/SIP-Skp1 unbiquitin ligase complex. …”

Lower insular perfusion in patients with hypoactive delirium compared with the non-DAT group. by Masashi Takeuchi (1930312)