Population dynamics modeling of split^50cM <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... by Georg Oberhofer (3401438)

“…(<b>G-I)</b> One way to appreciate the power of the latent drive force provided by LOF alleles that segregate independently of the <i>Rescue</i>/Cargo is to consider a split^50cM <i>ClvR</i> population in which a <i>Rescue</i>/Cargo/gRNAs with no fitness cost has spread to allele fixation, the Cas9 driver chromosome has been completely eliminated (as would happen during drive if the presence of Cas9 resulted in a fitness cost to carriers, discussed below), and all endogenous copies of the essential gene have been rendered LOF (generation 0 in <b>G-I</b>). …”

Fig 5 - by Marian Adan (16641634)

The distributions of the end-simulation adolescence-limited proportion when (a) <i>k</i> is increased or decreased by 50%, (b) <i>c</i> is increased or decreased by 50%, (c) <i>γ</i> is increased or decreased by 50%, and (d) Δ<i>e</i> is increased or decreased by 50%, compared against the benchmark distribution <i>F</i>(<b>p</b>₀) for the parameters shown in Table 1. by Jia Ning Leaw (752775)

Increased levels of PPARγ and decreased levels of adiponectin in thymus from rats administered cocaine for 7 days. by Kana Unuma (283272)

IL-1Ra expressed by MSCs decreased Th17 differentiation. by Kijun Lee (4888660)

Pairwise correlations of excitatory neurons in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Distribution of pulmonary ventilation assessed by center of ventilation (CoV) presented over the five time points: Induction-SB, MV-5min, MV-30min, MV-late and recovery-SB. by Milena S. Nascimento (14803681)

Decreased expression of adipogenesis-related genes by baicalein in early stage of adipogenesis. by Yukari Nakao (3138795)

“…Cells were prepared as described in the legend of Fig 5B. The data are presented as the value relative to that of the undifferentiated cells and are shown as the means ± S.D. from three experiments. …”

ROS and superoxide decrease in the dormant form of mycobacteria. by Amar Yeware (7115063)

P-V Fit Scores Across Demographic Factors Among 636 residents. by Yaotian Fan (5917766)

Subjects:

Mice carrying 100P mutations show layer-specific decreases in proportions of PV+ cells. by Malgorzata Borkowska (3166719)

“…<p>(<b>A-D</b>) Decreases occurred in layer IV in fSSp, SSp, vAud and Vis, in layer V in SSp, vAud and Vis and in layer II/III in SSp. …”

Effects of decreased cellulose on cell wall thickness. by Takumi Higaki (87635)

“…Data are mean ± SD (<i>n</i> = 5). **p < 0.005 (U-test). Note that thickness increased in the <i>rsw2/kor1</i> mutant. …”

Effects of Cu (5 µM) pretreatment on Hcy-induced decrease in cell viability and LDH release. by Daoyin Dong (424519)

The decrease of C/EBPα protein during apoptosis involves induction of protein degradation and inhibition of transcription. by Meng Zhao (54299)

“…Folds of decrease of C/EBPα protein/β-actin ratios against untreated cells are shown as means±SD of three independent experiments. …”

Calpeptin treatment decreases cell density and proliferation. by Daniela M. Santos (211055)

Sphere-forming efficiency decreases following radiation. by Vicky T. Nguyen (5029244)

Chronic intestinal inflammation persistently decreases frequency of mucosal CD5⁺ B cells. by Yoshiyuki Mishima (842248)

cDNA sequencing reveals missense point mutations in the UBA3 coding region of MLN4924-resistant K562 cells which decrease the sensitivity of NAE to MLN4924 in vitro. by G. Wei Xu (545673)

Tranilast decreases OC formation induced by RANKL. by Tien Van Phan (583324)

Tranilast decreases RANKL-induced ROS level. by Tien Van Phan (583324)