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22361
Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[<i>c</i>]phenanthrene and Its Metabolites: Synthesis, Physical, and Biological Properties
Published 2000“…However, there is an 11-fold increased activation of B<i>c</i>Ph dihydrodiol as compared to the 1,4-DMB<i>c</i>Ph dihydrodiol. …”
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22362
Kinetics of differential gene expression after rapid degradation of endogenous OGT in MEFs.
Published 2025“…Differentially expressed genes with p-value < 10<sup>−5</sup> and absolute log<sub>2</sub>FC > 0.3 (i.e. 1.2-fold increase or decrease in expression) are colored in red and their number is indicated. …”
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22363
Proteomic and phosphoproteomic time course over sexual differentiation.
Published 2024“…Details of all sites can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002963#pbio.3002963.s008" target="_blank">S1</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002963#pbio.3002963.s009" target="_blank">S2</a> Tables and on <a href="https://pombephosphoproteomics.unige.ch/" target="_blank">https://pombephosphoproteomics.unige.ch/</a>. (<b>D</b>) Fold enrichment for TORC, TORC1, TORC2, Orb6, and Cdc2 substrates among phosphosites that change (gray), decrease (blue) or increase (red) in abundance during starvation (top) and mating (bottom). …”
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22364
Regulation of <i>MMP7</i> expression by ASC and NLRP-3.
Published 2016“…An increase in MMP-7 and decrease in ASC staining were detected after infection of HTB-9 cells with CY-17 and CY-92 for 1 hour, compared to uninfected control cells. …”
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22365
Exploring the Scope of the 29G12 Antibody Catalyzed 1,3-Dipolar Cycloaddition Reaction
Published 2005“…These studies have shown that while 29G12 is specific for its dipole substrate <b>1a</b>, the antibody is highly promiscuous with respect to the dipolarophiles it can process. 29G12 accepts a bulky hydrophobic dipolarophile cosubstrate, with rates of product formation up to 70-fold faster than with the original substrate <b>2a</b>. …”
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22366
Dose-related neflamapimod (NFMD) subacute treatment effects on mNSS of rats with tMCAO.
Published 2020“…Significant mNSS differences were observed at both time point comparisons for 1.5 or 4.5 mg/kg neflamapimod dose groups compared to vehicle compared. …”
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22367
Inhibition of CXCR4 reduces inflammatory cell infiltration into the skin and normalizes epidermal architecture.
Published 2014“…(O–P) Computer-assesed quantification of epidermal thickness (O), number of intraepidermal BrdU<sup>+</sup> cells (P), the percentage of covered area by F4/80 (Q) and CD68 (R) postitive macrophages and the number of intraepidermal CD8<sup>+</sup> cells (S). Scale bars represent 100 μm. Data represent mean ±SD. <sup>*</sup>P<0.05; <sup>**</sup>P<0.01; <sup>***</sup>P<0.001.…”
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22368
<i>HMGA1</i> drives proliferation in intestinal mucosa and is overexpressed in colon cancer.
Published 2012“…(B) Ki-67 positive cells in <i>HMGA1</i> transgenic and control mice were enumerated in crypts of the small and large intestine at 20× magnification. The mean ± the standard deviations of Ki-67 positive cells per crypt for 100 crypts for each pair of mice at each location are shown. …”
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22369
Quantification of the synchronizing effect of local feedback inhibition.
Published 2015“…<p><b>A</b>, Mean spike time <i>μ</i><sub><i>p</i></sub> and variance <i>v</i><sub><i>p</i></sub> are calculated for the spike times in each pool <i>p</i> in simulation 1. …”
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22370
PERFORMANCE, CARCASS AND MEAT CHARACTERISTICS OF LAMBS IN FEEDLOT FED DIETS WITH INCREASING LEVELS OF FRESH ORANGE PULP REPLACING CORN
Published 2019“…The loin eye area and subcutaneous fat thickness decreased linearly as a function of the orange pulp inclusion levels in the diet. …”
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22371
Platelet thrombus formation on immobilized VWF in the presence of HbS.
Published 2016“…<p><b>(A)</b> Whole blood from healthy donor was perfused over immobilized VWF (100 μg/mL) under a shear stress of 25 dyne/cm<sup>2</sup> in the presence of HbS. …”
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22372
ERR2/3 expressed by gamma motor neurons is required for normal locomotion and precision movements.
Published 2022“…<b>(D)</b> ERR2/3<sup>cko</sup> (18.0 ± 1.75, 55.0 ± 2.20, 79.0 ± 3.49) but not control (1.0 ± 0.175, 1.0 ± 0.125, 1.0 ± 0.125) mice exhibit dramatically increasing erratic locomotion (18-, 55-, and 79-fold increase in the # of misses) upon navigating horizontal beams with decreasing width 30 mm, 25 mm, and 20 mm, respectively (control <i>N =</i> 4, ERR2/3<sup>cko</sup> <i>N</i> = 4, 4–5 trials/animal). …”
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22373
ACh signals measured in rat mPFC by Howe et al. during the SAT.
Published 2022“…Prior signal probability <i>p</i><sub>1</sub> switches between 0.1 and 0.15, with parameters otherwise fixed as follows: <i>q</i> = 0.2, <i>σ</i><sub><i>w</i></sub> = 1, <i>σ</i><sub><i>s</i></sub> = 0.5, <i>κ</i> = −0.1, <i>ϵ</i> = −0.005, <i>δ</i> = 0.001. …”
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22374
Violin plot showing the distribution of the self-selected overground (OG) walking speeds and the fixed treadmill (TM) speed for each participant group.
Published 2022“…Whiskers extend from the bottom of the box to the smallest observation within 1.5 times the interquartile range. Whiskers similarly extend from the top of the box to the largest observation within 1.5 times the interquartile range. …”
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22375
LTX-401 rapidly induces cell death in B16F1 melanoma cells.
Published 2016“…<p>The determination of cell viability after a short incubation at two different concentrations of LTX-401 was analyzed after designated time points (5, 15, 30, 60, 90, 120 and 240 minutes), which revealed a decreased viability after 60 minutes of incubation. …”
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22376
Data_Sheet_1_Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery.xlsx
Published 2021“…At 2 years post-operatively, they were able to maintain their preoperative level (22.6 ± 5.3). The patients were classified in to the cognitive decline group [11 (23%) patients; a decrease in the MMSE score by ≥ 2 points 2 years after surgery] and the maintenance/improvement group [37 (77%) patients]. …”
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22377
Assessing the impact of climate changes on the distribution of two corn diseases: corn stunt and corn reddening
Published 2025“…On the other hand, for SSP5–8.5, Maxent predicted that suitable CS and CR habitat will decrease by 2060 in the United States, China and Brazil. …”
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22378
Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
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22379
Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
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22380
Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”