Astrocytic glutamate regulates transitions between facilitation and depression at the same synapse. by Maurizio De Pittà (194237)

“…<p>(<b>A</b>,<b>B</b>, <i>left</i>) Raster plots of a depressing synapse, without (<b>A</b>) and in presence of (<b>B</b>) a single event of glutamate exocytosis from the astrocyte (onset at the <i>black mark</i> at <i>t</i> = 1 s, α = 0) for <i>n</i> = 100 Poisson spike trains with the same average frequency <i>f_in</i> (<i>black line</i> in <b>A</b>,<b>B</b>, <i>right</i>). …”

AID induces demethylation independent of the nucleotide context. by Don-Marc Franchini (266869)

“…Loss of <i>m6</i>A is shown in (<b>B</b>) by a decrease in recovery after <i>Mbo</i>I cutting versus uncut, and by an increase in recovery after <i>Dpn</i>I digest (<b>C</b>). …”

Subnetworks having different frequency preferences can synchronize their activity if they share gap junctions. by Guillaume Pernelle (4951924)

“…(<b>C</b>) Changing the single neuron sub-threshold resonance modifies the network oscillation frequency. Mean inhibitory membrane potential for <i>τ</i>_<i>v</i> = 17 ms (continuous line) and <i>τ</i>_<i>v</i> = 55 ms (dashed line). 100 ms of data is represented. …”

Data_Sheet_1_Elevated concentrations of macrophage migration inhibitory factor in serum and cerebral microdialysate are associated with delayed cerebral ischemia after aneurysmal s... by Felix Neumaier (4391794)

“…MD levels peaked during EP_d1−4, decreased during CP_d5−15 and increased again during LP_d16−21. …”

Chemical, physical and biological changes of white oat ensiled with different additives by Américo Fróes Garcez Neto (6141833)

“…The non-fiber carbohydrates (NFC) decreased (16.67 to 14.05% DM) and the crude protein (CP) did not change (mean of 8.98% DM) during the aerobic exposure in all silages. …”

Gender and Productivity Differentials in Smallholder Groundnut Farming in Malawi: Accounting for Technology Differences by Eric S. Owusu (11859910)

“…The results reveal different production technologies in use by male and female producers, and technology (6–7 per cent points) and managerial (3–5 per cent points) differentials, which translate into significant male advantages in land productivity (6.2 per cent) and TFP (15.3 per cent). …”

Drug Absorption Efficiency in <em>Caenorhbditis elegans</em> Delivered by Different Methods by Shan-Qing Zheng (382120)

“…</p> <p>Methodology/Principal Findings</p><p>We evaluated the drug absorption efficiency in <i>C. elegans</i> using five frequently used methods with resveratrol with low aqueous solubility and water-soluble 5-Fluoro-2′-deoxyuridine (FUDR) as positive compounds. …”

Simulation of constant current injection into the B1 motoneuron in normal saline and with octopamine by Ágnes Vehovszky (14366)

“…A further increase in excitability is seen. Decreasing the maximum sodium conductance reduces the number of action potentials (diamonds). …”

Mesenchymal nuclei and Collagen-I align with mechanical strain. by Jon Riddell (4240438)

“…<p><b>(A)</b> Plot showing the percentage decrease in anterior-posterior (A-P) and dorsal-ventral (Lat) length of mouse skin explants in a 30 min period (<i>n</i> = 5) when suspended freely in culture medium. …”

<i>Macmoondongtang</i> treatment suppressed infiltration of both inflammatory cells and immune cells such as white blood cells (WBCs), eosinophils, and neutrophils. by Soon-Young Lee (4721136)

“…<p>(A) <i>Macmoondongtang</i> effectively decreased OVA-induced proliferation of inflammatory cells. …”

Wnt/β-catenin signaling is increased in the <i>Fuz</i> null mice. by Zichao Zhang (344301)

“…Canonical Wnt target gene expression was increased whereas non-canonical Wnt pathway gene expression was decreased. β-actin served as the reference gene. Experiments were repeated three to five times each from multiple samples. …”

HSV-2-specific CD4⁺ and CD8⁺ T cell responses are detected in HSV-2/SHIV-RT co-infected animals. by Federica Crostarosa (256646)

“…(D) Approximately 12 months after challenge with SHIV-RT or co-challenge with HSV-2/SHIV-RT, the fold decreases in CD4 counts (mean±SEM, relative to pre-exposure levels) (left axis, stars) and plasma viral loads (mean RNA copies/ml±SEM, right axis, circles) are shown (n = 5 for both).…”

Inverse correlation of C/ebpβ and <i>Arf</i> expression during Tgfβ treatment. by Yanbin Zheng (442029)

“…The data is plotted as the fold changes of target genes from cells treated with Tgfβ (T) (5 ng/ml) versus the same cells treated with vehicle (V) (4 mM HCl). …”

Equilibrium binding of single strand DNA (P1) from promoter with mNdK by Praveen Kumar (8242)

“…CD spectra of P1 (4 μM) shows decrease in ellipticity at 285 nm with increasing mNdK (0–0.5 μM) in 50 mM Tris-MES-acetate pH 6.5, 1 mM MgCl, 75 mM NaCl within 30 min of incubation, after each addition, at 37°C. () Enzymatic (phosphotransfer) activity of mNdK at pH 6.5. …”

Luciferase assay results of <i>KATNA1</i> and <i>SPG4</i>. by Dolunay Kelle (6388055)

“…Luciferase assay was performed 48 h post-transfection, and calculated fold activities indicated that wt-Elk1 significantly decreased promoter + 5’ UTR activity of <i>KATNA1</i>. …”

Temporary proliferation and neurogenesis defects upon CR cells ablation. by Amélie Griveau (245148)

“…For all quantifications, histograms represent numbers of cells per 100 µm (mean ± s.e.m) for controls (white) and mutant embryos (black). …”

Blood Pressure Modifies Retinal Susceptibility to Intraocular Pressure Elevation by Zheng He (137369)

“…Elevated intraocular pressure (IOP) is a risk factor for glaucoma and may reduce nutrient availability by decreasing ocular perfusion pressure (OPP). …”

Prostate-specific antigen, androgen, progesterone and oestrogen receptors in Benign prostatic hyperplasia: human tissues and animal model study by Haohan Wang (8488557)

“…<p>Direct evidence for the relationship between a large prostate (≥80 ml) and androgen receptor/PSA signal remains lacking in benign prostatic hyperplasia (BPH). …”

CRISPRi knockdown of Lon protease to increase half-life. by Nicholas A. Rossi (3622865)

“…Bivariate scatter plots show P_<i>inaA</i> and P_<i>acrAB</i> expression levels at the final time point across n = 5 microcolonies. The two distributions are statistically different by the 2D Kolmogorov-Smirnov test, p<0.001. …”

POPULATION STRUCTURE OF THE NELLORE HERD REARED IN THE BRAZILIAN NORTHEAST SEMI-ARID by Marcos Paulo Gonçalves Rezende (6119768)

“…The individual with the highest expression presented a mean coefficient of relationship (CR) of 1.31%, explaining 1.81% of the variability.72% of animals have identified fathers and mothers, revealing loss of information between generations. 100% of the herds use external bulls and 61% of them sell bulls, with no core classification or isolate. …”