VPA and NAM treatment modulates H3K27 acetylation at the promoters of myeloid specific genes. by Marije Bartels (532852)

“…Data represent a Venn diagram comparing the number of genes identified based on a >2-fold increase or decrease in H3K27 acetylation levels compared to the control (A). …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Table 2_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Table_1_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.xlsx by Fiona S. McDonnell (17106334)

“…</p>Results<p>Results showed changes in the percentage of ECM proteins associated with EVs from glaucomatous TM cells compared to non-glaucomatous TM cells (5.7% vs 13.1% respectively). Correspondingly, we found that two ECM-related cargo proteins found across all samples, fibronectin and EDIL3 were significantly less abundant in glaucomatous EVs (<0.3 fold change across all groups) compared to non-glaucomatous EVs. …”

DataSheet_1_National patterns of paroxetine use among US Medicare patients from 2015–2020.docx by Luke R. Cavanah (19022435)

“…</p>Results<p>Nationally, there was a steady decrease in population-corrected paroxetine prescriptions (-34.52%) and spending (-29.55%) from 2015–2020 but a consistent, five-fold state-level difference. …”

High Performance Liquid Chromatography and Metabolomics Analysis of Tannase Metabolism of Gallic Acid and Gallates in Tea Leaves by Mingli Liu (304361)

“…In this work, we measured tannase in <i>Aspergillus niger</i> fermented tea leaves and confirmed the production of fungal tannase during pu-erh tea fermentation. A decrease in catechin and theaflavin gallates and a significant increase in GA content and the relative peak areas of ethyl gallate, procyanidin A2, procyanidin B2, procyanidin B3, catechin-catechin-catechin, epiafzelechin, and epicatechin-epiafzelechin [variable importance in the projection (VIP) > 1.0, <i>p</i> < 0.05, and fold change (FC) > 1.5] were observed using high performance liquid chromatography (HPLC) and metabolomics analysis of tea leaves fermented or hydrolyzed by tannase. …”

High Performance Liquid Chromatography and Metabolomics Analysis of Tannase Metabolism of Gallic Acid and Gallates in Tea Leaves by Mingli Liu (304361)

“…In this work, we measured tannase in <i>Aspergillus niger</i> fermented tea leaves and confirmed the production of fungal tannase during pu-erh tea fermentation. A decrease in catechin and theaflavin gallates and a significant increase in GA content and the relative peak areas of ethyl gallate, procyanidin A2, procyanidin B2, procyanidin B3, catechin-catechin-catechin, epiafzelechin, and epicatechin-epiafzelechin [variable importance in the projection (VIP) > 1.0, <i>p</i> < 0.05, and fold change (FC) > 1.5] were observed using high performance liquid chromatography (HPLC) and metabolomics analysis of tea leaves fermented or hydrolyzed by tannase. …”

Transcriptional downregulation of Bcl-2 is critical to mediate PMC-A induced apoptosis. by Cagri Bodur (282762)

“…HCT116 wt cells were treated with indicated PMC-A concentrations, harvested after 24 h for total RNA extraction, cDNA synthesis and qRT-PCR analysis (B). A marginal (∼5-fold) decrease in Bcl-2 transcription was evident upon PMC-A treatment (p<0,01). …”

VEGF reduces miR-30b expression in HUVECs. by Grant A. Howe (2558611)

“…(B) Cells were serum starved overnight in MCDB 131 with 0.5% FBS and stimulated with VEGF (50 ng/ml) for 24 hours. …”

Table 3_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.csv by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Gene expression comparison between <i>C. albicans</i> alone and drug-treated groups in <i>Galleria mellonella</i>. by Nadja Rodrigues de Melo (485602)

“…On the other hand this treatment also caused a significant decrease of gene expression of IMPI, C5 (*p<0.001), C6 and C7 (**p<0.05). …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Table 4_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Association between changes in miRNA 3′ nucleotide additions and changes in miRNA abundance. by Emily C. Knouf (434880)

“…Shading of a box indicates a t-test p-value <0.05 when comparing the abundance in miRNAs with unchanged versus increased or decreased 3′ addition. (<b>D</b>) MicroRNAs with increased 3′ U additions show significant decreases in abundance compared to miRNAs with unchanged additions (t-test, p-value <2×10⁻⁵).…”

Sex-specific effect of WT1 and GATA4 knockdown on <i>Gata4 E1a</i> and <i>Gata4 E1b</i> isoforms expression. by Lucas J. Rudigier (3938090)

“…WT1 knockdown resulted in a significant decrease of <i>Gata4 E1b</i> and <i>Gata4 E1a</i> transcripts in XY gonads but not in XX gonads. …”

Image1_Arum palaestinum delays hepatocellular carcinoma proliferation through the PI3K-AKT-mTOR signaling pathway and exhibits anticoagulant effects with antimicrobial properties.j... by Majdi Dwikat (16002338)

“…The aqueous extract of AP 1) reduced secretions of HCC αFP by 1.55-fold and 3.3-fold at the 50 and 100 μg/mL concentrations, respectively (p = 0.0008); 2) decreased phosphorylation in the PI3K-AKT-mTOR signaling pathway (p < 0.05); and 3) shifted cells from necrosis to apoptosis by 50% and 70% at the 50 and 100 μg/mL concentrations, respectively (p < 0.05).…”

Analysis of dopant diffusion in molten germanium induced by pulsed nd : yag laser by Mousa, Ali M. [علي مطشر موسى]

“…Doped sample Tann = 200- 500 C for time t mn = 45 subjected to subsequent thermal annealing (at the temperature and to plused leacr annealing (en<5rgy density in a min) pluse E=5.2 - 9.5 J/cm2) in order to establish optimal condition. …”
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Roles of HSC70 and Cofactor DjA1 in KCNQ4 Biogenesis. by Yanhong Gao (244711)

“…Knockdown of HSC70 or DJA1 resulted in a significant decrease in total KCNQ4 level. Each data point in the bar graphs represents the mean ±SD of three experiments (* p≤0.05, ** p≤0.01).…”

Contraction of porous 70:30 col/PCL scaffolds containing seeded fibroblasts. by Paul P. Bonvallet (708039)

“…<p>Scaffold diameters were measured at each time interval to quantify contraction (plotted as percent decrease in scaffold diameter). Values represent means and standard deviation for five scaffolds per time point. …”

Dose response inhibition of IP6K1 by TNP in the presence of different concentrations of ATP and IP6. by Michael Wormald (4631122)

“…(B) IC₅₀ values decreased slightly from 24±1.5μM to 9.5±1.5μM as IP6 concentrations were increased from 50μM to 400μM. …”