Pharmacological inhibition of cell death pathways protects neurons against glutamate-induced cell death. by Ujval Anilkumar (4598182)

“…Traces show that blocking key cell death signalling pathways protected neurons against excitotoxicity. B) A heat map of the median population of viable cells 24 h following glutamate excitation (100 μM) illustrates the protective effect of these drugs against glutamate-induced cell death. …”

<i>H</i>. <i>pylori</i> TlpD-dependent chemoattraction to sources of HOCl. by Arden Perkins (1346853)

“…<p>(A) Data from point-source chemotaxis experiments [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000395#pbio.3000395.ref021" target="_blank">21</a>] are shown for <i>H</i>. …”

<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

“…In vivo, 263<i>ΔStiP</i>-infected mice exhibited 5-, 7-, and 4-fold lower bacterial loads in blood, liver, and spleen (P < 0.001), respectively, with reduced pathological damage versus WT263. …”

Specificities mediating neutralization breadth and potency in the top 42 Protocol C neutralizers. by Elise Landais (845745)

“…Absent (-), very weak (+/-), weak (+), moderate (++), strong (+++), phenotype was attributed based on i) the median fold or average percent decrease in ID50 and ii) the fraction of viruses which neutralization ID50 was decreased <2 fold, <10 <50 fold or <20%, <40%, <60%, <80%. …”

A model of the effect of the Bar1 protease on yeast signaling. by Steven S. Andrews (251777)

“…These data fit well to Hill functions with unit cooperativity but with a 5-fold difference in their EC₅₀s. (C) Average gradient of GPCR-α complexes across the surface of the <i>MAT</i><b>a</b> cell. …”

Protein expression changes induced by CIE paradigm. by Giorgio Gorini (497793)

“…The pie charts show the amount of protein that increases and decreases within three ranges: 5-15%, 16-20%, >20% (absolute values); the numbers in brackets indicate the number of protein spots in that category. …”

Suppression of <i>cac</i>^<i>TS2</i> temperature-sensitive seizure-like activity by <i>para</i>^<i>bss1</i>. by Arunesh Saras (846011)

“…Compared <i>to cac</i>^<i>TS2</i> single mutants (white bar), <i>para</i>^<i>bss1</i><i>cac</i>^<i>TS2</i> double mutants (gray bar) exhibit 5 fold decrease in TS seizure-like behaviors. Quantitative data are represented as mean ± s.e.m. …”

The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data by The WorldWide Antimalarial Resistance Network (WWARN) DP Study Group (614261)

“…After adjusting for confounding factors, the mg/kg dose of piperaquine was found to be a significant predictor for recrudescence, the risk increasing by 13% (95% CI 5.0%–21%) for every 5 mg/kg decrease in dose; <i>p</i> = 0.002. …”

Steady state changes in leading edge activity sensors following modulator addition. by Brian P. Ziemba (327744)

“…Filled bars represent the fold change as the activity approaches a new steady state level approximately 5 min after modulator addition (t = 4.5 to 5.5 min (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0196678#sec012" target="_blank">Methods</a>)). …”

Table1_Early long-term low-dosage colchicine and major adverse cardiovascular events in patients with acute myocardial infarction: a systematic review and meta-analysis.docx by Yifang Zhou (553482)

“…</p>Results<p>Eight studies identified from 564 screened records were analyzed, with 5,872 patients after AMI. The length of follow-up varied from five days to 22.7 months, and 0.5–1.0 mg colchicine was administered daily. …”

Distance from the optimal direction for different levels of reward probabilities. by Jyotika Bahuguna (729510)

“…<p>A) DDM (a, v) and behavioral (RT, accuracy) parameters for reward probabilities: 100% (red), 95% (pink), 90% (yellow) and 75% (khaki) measured for 150 networks. …”

Cell cycle analysis of dinaciclib in apoptotic-proficient and apoptotic-deficient cell lines. by Robert N. Booher (640925)

“…<p>(A) Apoptotic-deficient CA46 cells and apoptotic-proficient Kasumi-1 cells were treated for 24 hr with dinaciclib (100 nM) or mitotic inhibitor paclitaxel (3 µM). …”

Histamine activates both transient and persistent [Ca]_i responses. by Iustin V. Tabarean (302441)

“…The TRPC channel blocker SKF96365 (100 µM) decreases the histamine activated [Ca]_i plateau but does not affect the transient increase activated by the neurotransmitter. …”

TLR4 took part in HMGB1-induced activation of NF- by Fu-ping Wang (5659540)

“…Compared to the HMGB1 stimulation, TLR-4 neutralizing antibody pretreatment resulted in a decrease in NF-kB protein level as well as in phospho-IkBα level, while a concomitant increase in the cytosolic IkBα protein level. …”

Low fertility and postponement of first birth in Brazil by Adriana Miranda-Ribeiro (7453322)

The effect of size and density on nut removal in Syagrus loefgrenii Glassman (Arecaceae) in the Brazilian Cerrado by J. Ragusa-Netto (4895749)

The mean Brier score for the logistic regression models. by Denis A. Shah (10305663)

Knife, carver, jackknife: an analysis of the femicide law in Brazil by Carlos Barreto Campello Roichman (10354756)

Influence of activated carbon porosity and surface oxygen functionalities’ presence on adsorption of acetonitrile as a simple polar volatile organic compound by Sylwester Furmaniak (692416)

Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…Each junction was analyzed separately, and for each junction genes included in the analysis (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048084#s3" target="_blank">Materials and Methods</a>) were divided into categories of increased (Up), decreased (Down) or unchanged (less than 2-fold change in any direction) U2AF65 counts in a region of +/−100 nt around the corresponding junction. …”