Data Sheet 3_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.</p>Results<p>A total of 897 DEGs were identified, with functional enrichment analysis revealing significant involvement in T cell activation (p=2.84×10^-3), neuroactive ligand-receptor interaction (p=6.01×10^-4), and osteoclast differentiation (NES=2.83). …”

Data Sheet 4_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.</p>Results<p>A total of 897 DEGs were identified, with functional enrichment analysis revealing significant involvement in T cell activation (p=2.84×10^-3), neuroactive ligand-receptor interaction (p=6.01×10^-4), and osteoclast differentiation (NES=2.83). …”

Effect of Intramuscular Injection of pH, lactate, ATP, and α,β–meATP on Muscle Withdrawal Threshold. by Nicholas S. Gregory (796912)

“…Of these doses, only pH 4.0 saline produced a significant decrease in muscle withdrawal threshold from baseline (Repeated measures ANOVA, F_4,31 = 16.761, p <0.001, Tukey test, p < 0.001). …”

<i>vang-1(tm1422)</i> life span modulation depends on Insulin/IGF-1-like signaling and leads to higher DAF-16 activity. by Sebastian J. Honnen (183696)

“…</b> Depletion of DAF-2 by RNAi in <i>tm1422</i> (brown spotted line) and WT (green solid line) causes an increase of mean life span to <b>25.6±1.3 d</b> (n = 135*) and <b>25.8±1.1 d</b> (n = 126*), respectively (p<0.62**), which is in agreement with published results for <i>daf-2</i> mutants <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032183#pone.0032183-Hertweck1" target="_blank">[23]</a>. …”

Comparison of molecular and metabolic changes caused by 24 hours treatment of SF188 pediatric glioblastoma cells with PI-103 or TMZ at 2×GI₅₀. by Nada M. S. Al-Saffar (454143)

The binding of HP1γ and cohesin to D4Z4 is lost in FSHD patients. by Weihua Zeng (262054)

“…Cohesin ChIP was compared to that of condensin, another major SMC-containing complex, and protein A beads control. (D) ChIP PCR analyses using 4qHox primers of HP1γ and cohesin binding in H, PF and 4qF fibroblasts as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000559#pgen-1000559-g003" target="_blank">Figure 3B</a>. …”

Image_1_The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.tif by Noel E. Donlon (12006569)

“…A simultaneous increase was observed in Th2 cytokines in the immediate post-operative setting, with a significant increase in IL-4, IL-10, IL-16 and MCP-1 before returning to preoperative levels at week 6.…”

Image_3_The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.tif by Noel E. Donlon (12006569)

“…A simultaneous increase was observed in Th2 cytokines in the immediate post-operative setting, with a significant increase in IL-4, IL-10, IL-16 and MCP-1 before returning to preoperative levels at week 6.…”

Image_4_The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.tif by Noel E. Donlon (12006569)

“…A simultaneous increase was observed in Th2 cytokines in the immediate post-operative setting, with a significant increase in IL-4, IL-10, IL-16 and MCP-1 before returning to preoperative levels at week 6.…”

AZD8055, an mTOR inhibitor stimulates neuronal autophagy by inducing Atg4b-dependent autophagy flux in cultured neurons. by Catia C. Proenca (431486)

“…AZD8055 treatment led to a significant increase in autophagy flux observed by a decrease in p62 level. …”

Image_2_The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.tif by Noel E. Donlon (12006569)

“…A simultaneous increase was observed in Th2 cytokines in the immediate post-operative setting, with a significant increase in IL-4, IL-10, IL-16 and MCP-1 before returning to preoperative levels at week 6.…”

Table_1_The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition.pdf by Noel E. Donlon (12006569)

“…A simultaneous increase was observed in Th2 cytokines in the immediate post-operative setting, with a significant increase in IL-4, IL-10, IL-16 and MCP-1 before returning to preoperative levels at week 6.…”

Ultra-processed foods consumption is associated with cardiovascular disease and cardiometabolic risk factors in Brazilians with established cardiovascular events by Alessandra da Silva (4518985)

Factors associated with bite force in people with Parkinson's disease by Taysa Vannoska de Almeida Silva (4650682)

Intense Exercise and Aerobic Conditioning Associated with Chromium or L-Carnitine Supplementation Modified the Fecal Microbiota of Fillies by Maria Luiza Mendes de Almeida (3390041)

“…Twelve “Mangalarga Marchador” fillies in the incipient fitness stage were distributed into four groups: control (no exercise), exercise, L-carnitine (10g/day) and chelated chromium (10mg/day). In order to investigate the impact of acute exercise or aerobic conditioning on fecal microbiota all fillies undergoing the conditioning program were analyzed as a separate treatment. …”

Levels of mRNA expression in chondrodystrophic NP in 3D cultures. by Munetaka Iwata (322242)

“…At early time points (day 0 and 5), agarose cultures exhibited lower expression of <i>Col2A1</i> and <i>ACAN</i> than monolayer cultures (p<0.01). …”

Accumulation and localization of CDKA;1-YFP fusion protein during female and male gametophyte development. by Xin'Ai Zhao (146720)

“…<p>(A-A^VI) Expression of a <i>PRO_CDKA;1:CDKA;1-YFP</i> construct completely rescues <i>cdka;1</i> pollen resulting in wild-type-like pollen with one vegetative cell (arrowhead in A^V) and two sperm cells (triangle in A^V and A^VI, see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002847#pgen-1002847-g001" target="_blank">Figure 1</a>). …”

TRIM5α induces an antiviral state following infection with restricted viruses. by Natacha Merindol (3521828)

“…The total percentage of GFP⁺ cells is shown in bold. <b>(b)</b> Fold decreases in NRC1_GFP (n = 25) and NRC10_GFP (n = 17) infectivity in T5KO and control (CAG) Jurkat cells subjected to a first infection with isolates-derived DsRed-vectors. …”

MALDI-TOF mass spectra obtained for <i>Lb</i>. <i>paracasei</i> subsp. <i>paracasei</i> F19 in the mass range from 2 000 Da to 15 000 Da. by Ann-Sophie Schott (3269931)

“…<p>Control conditions (control) and sublethal potassium chloride at different sampling points are indicated. Dotted line 1 marks a single peak at approx. 6 991 m/z (1) with decreasing peak intensity. …”

The Gc fusion loops. by Pablo Guardado-Calvo (2325709)

“…C) For comparison, the same representation of flavivirus E (Dengue 2, 1OK8; [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005813#ppat.1005813.ref053" target="_blank">53</a>]) and D) phlebovirus Gc (RVFV, 4HJ1; [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005813#ppat.1005813.ref020" target="_blank">20</a>]) fusion loop region. …”