Largazole (L) and largazole ester (E) inhibit ubiquitin E1 in a dose dependent manner <i>in vitro</i>. by Dana Ungermannova (334910)

“…In addition, DMSO has no effect on the formation of the thioester linkage as seen in lane 2 of both gels. 50 nM E1 was incubated with decreasing concentrations of L (A) or E (C) for 15 minutes at room temperature followed by addition of a cocktail containing ATP and Ub-F. …”

Data_Sheet_1_Application of Fractions of Crop Evapotranspiration Affects Carbon Partitioning of Grapevine Differentially in a Hot Climate.docx by Nazareth Torres (3571967)

“…Likewise sucrose:N ratio and root non-structural carbohydrates decreased with the lower applied water. Altogether, carbon allocation between the source and sink organs likely controlled the response of grapevines to water deficits in a hot climate, and replacing 50% ET_c was sufficient to sustain the grapevine performance given the enhancement of sugar transport, which could slow down the detrimental effect of water deficits on yield.…”

Using Micro-Computed Tomography to Evaluate the Dynamics of Orthodontically Induced Root Resorption Repair in a <i>Rat</i> Model by Xiaolin Xu (493031)

“…From day 3 to day 10, the 20-g group exhibited faster relapse than the 50-g and 100-g groups. In all groups, the structure model index and trabecular separation decreased slowly from day 0 to day 10 and eventually stabilized. …”

DataSheet_1_Incidence of Immune Checkpoint Inhibitor-Associated Diabetes: A Meta-Analysis of Randomized Controlled Studies.pdf by Jingli Lu (486220)

“…Fifty-two RCTs were included, and 12 did not report any events of ICI-associated diabetes.</p><p>Results: A meta-analysis of 40 trials was performed, which reported at least one diabetes-related event among 24,596 patients. …”

DataSheet_1_Incidence of Immune Checkpoint Inhibitor-Associated Diabetes: A Meta-Analysis of Randomized Controlled Studies.pdf by Jingli Lu (486220)

“…Fifty-two RCTs were included, and 12 did not report any events of ICI-associated diabetes.</p><p>Results: A meta-analysis of 40 trials was performed, which reported at least one diabetes-related event among 24,596 patients. …”

Table_1_Relationship Between Dairy Products Intake and Risk of Endometriosis: A Systematic Review and Dose-Response Meta-Analysis.docx by Xiangying Qi (9989599)

“…Total dairy intake was inversely associated with the risk of endometriosis, and the risk of endometriosis tended to decrease with a decrease in the risk of endometriosis when dairy products intake was over 21 servings/week (RR 0.87, 95% CI 0.76–1.00; p_{non−linearity} = 0.04). …”

Effects of immersive virtual reality therapy on intravenous patient-controlled sedation during orthopaedic surgery under regional anesthesia: A randomized controlled trial by Mark Y. Huang (8486583)

“…<div><p>Background</p><p>Immersive virtual reality (IVR) is a form of distraction therapy that has shown potential as an analgesia and sedation sparing agent. …”

Sacrifice Template Strategy to the Fabrication of a Self-Cleaning Nanofibrous Membrane for Efficient Crude Oil-in-Water Emulsion Separation with High Flux by Mingming Wu (268965)

“…However, most materials are extremely susceptible to pollution during oil–water separation, which drastically restricts their widespread applications. Herein, a momordica-charantia-like nanofibrous membrane (MCNM) with underwater superoleophobic performance was fabricated through a sacrifice template strategy by the electrospinning solution of zeolitic imidazolate framework-8 (ZIF-8) and polyacrylonitrile particles. …”

Dynamic variations of cell populations given distinct impacts of Aβ on M1 macrophages (the value of α₁₃). by Ishwar K. Puri (358815)

“…<p>Variations in the (a) M₁, (b) N_d and (c) Aβ populations over 20 years for three values of α₁₃  =  1× (black), 10× (red), and 50× (blue) the value reported in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015176#pone-0015176-t001" target="_blank">Table 1</a> for the path Aβ → M₁. …”

Inferring causal pathways among three or more variables from steady-state correlations in a homeostatic system - Fig 4 by Suraj Chawla (5848265)

Summary of correlations in previous studies. by Dan Kuang (136225)

“…Furthermore, the infection rates of SARS-CoV-2, as estimated by the model, ranged from 0.012% (P5-P95: 0.004% - 0.020%) at the lowest baseline to 3.27% (P5-P95: 1.23% - 5.69%) at the peak of the epidemic, with 15.1% (P5-P95: 5.65% - 26.2%) of individuals infected during the epidemic wave between March 4th and June 15th. …”

The characteristics of nine WWTPs. by Dan Kuang (136225)

“…Furthermore, the infection rates of SARS-CoV-2, as estimated by the model, ranged from 0.012% (P5-P95: 0.004% - 0.020%) at the lowest baseline to 3.27% (P5-P95: 1.23% - 5.69%) at the peak of the epidemic, with 15.1% (P5-P95: 5.65% - 26.2%) of individuals infected during the epidemic wave between March 4th and June 15th. …”

Neurons in the hippocampal CA1 region 14 days after resuscitation. by Xin Liu (43569)

Pre- and Neonatal Exposure to Lipopolysaccharide or the Enteric Metabolite, Propionic Acid, Alters Development and Behavior in Adolescent Rats in a Sexually Dimorphic Manner by Kelly A. Foley (512965)

“…Pregnant Long-Evans rats were subcutaneously injected once a day with PPA (500 mg/kg) on gestation days G12–16, LPS (50 µg/kg) on G15–16, or vehicle control on G12–16 or G15–16. …”

Unhelped virus-specific CD8 T cells in the brain remain functional. by Taryn E. Mockus (5905130)

Oxa33, a novel inhibitor against GlmU_Mtb binds at allosteric site of uridyltransferase domain. by Vijay Soni (816694)

“…<b>(F)</b> Superimposed view of GlmU_Mtb-Oxa33 complex before (green) and after (orange) the simulation time period. Showing a partial closure of uridyltransferase site (decreased volume) thereby making it unavailable for its substrates for catalysis.…”

Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx by Youqiong Xu (18161893)

“…Adherence to a healthy lifestyle (favorable [OR = 0.69, 95%CI: 0.59–0.82] and extremely favorable [OR = 0.54, 95%CI: 0.43–0.68]) was associated with a reduced risk of multiple comorbidities, with a trend toward a decreased risk of multiple comorbidities as the number of healthy lifestyles increased (p < 0.001). …”

DataSheet_1_Effect of Ketamine on Limbic GABA and Glutamate: A Human In Vivo Multivoxel Magnetic Resonance Spectroscopy Study.docx by Leo R. Silberbauer (9352769)

“…Thus, this study aimed to investigate subacute changes in cerebral Glx (glutamate + glutamine), GABA and their ratio in seven brain regions central to depressive pathophysiology and treatment.</p>Methods<p>Twenty-five healthy subjects underwent two multivoxel MRS scans using a spiral encoded, MEGA-edited LASER-localized 3D-MRSI sequence, at baseline and 2 h following intravenous administration of racemic ketamine (0.8 mg/kg bodyweight over 50 min). …”

Women's Education Level, Maternal Health Facilities, Abortion Legislation and Maternal Deaths: A Natural Experiment in Chile from 1957 to 2007 by Elard Koch (166600)

“…</p> <h3>Results</h3><p>During the 50-year study period, the MMR decreased from 293.7 to 18.2/100,000 live births, a decrease of 93.8%. …”

Table_2_Risk of Venous Thromboembolism in Transgender People Undergoing Hormone Feminizing Therapy: A Prevalence Meta-Analysis and Meta-Regression Study.docx by Maria Totaro (11665708)

“…Further studies are warranted to assess whether different types and administration routes of estrogen therapy could decrease the VTE risk in AMAB trans people over 37.5 years subjected to long-term therapy.…”