Data Sheet 1_Insulin resistance assessed by estimated glucose disposal rate is associated with all-cause and cardiovascular mortality among postmenopausal women.docx by Han Qian (6063431)

“…A U-shaped relationship between eGDR and all-cause mortality was identified, with an inflection point at 5.11 mg/kg/min. Subgroup analyses revealed a stronger association between eGDR and all-cause as well as cardiovascular mortality in individuals younger than 60 years.…”

Supplemental file for Training alters cytokine and soluble receptor responses by Jeremy Ducharme (20174820)

“…Following 1-hour of cycling at their respiratory compensation point, untrained men (n=5) exhibited a significant increase in pro-inflammatory cytokines, including IL-6, TNF-α, IL-1β, CCL2, and VEGFA. …”

Image_3_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_2_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_1_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Table_1_Improving Mood and Cognitive Symptoms in Huntington's Disease With Cariprazine Treatment.DOCX by Maria Judit Molnar (7609673)

“…Cariprazine treatment resulted in the following changes from BL to week 12, respectively: the mean score of BDI decreased from 17.7 ± 10.7 to 10.0 ± 10.7 (p <0.0097), while the Behavioral Assessment score of the UHDRS decreased from 54.9 ± 11.3 to 32.5 ± 15.4 (p < 0.0001); ACE score increased from 75.1 ± 11.0 to 89.0 ± 9.3 (p < 0.0001); Cognitive Verbal Fluency score from 6.2 ± 2.5 to 7.7 ± 2.7 (p < 0.0103); Symbol Digit Test from 9.2 ± 6.9 to 12.3 ± 8.9 (p < 0.0009). …”

GRP-R mAb-1 inhibitory roles on neuroblastoma cell <i>in vitro</i>. by Jingbo Qiao (382330)

“…The green fluorescence signal indicated the released intracellular Ca²⁺ in SK-N-AS cells (left). The mean of green fluorescence intensity was quantified with Gen5 Software (right). …”

Data_Sheet_1_Shelterbelt Poplar Forests Induced Soil Changes in Deep Soil Profiles and Climates Contributed Their Inter-site Variations in Dryland Regions, Northeastern China.pdf by Yan Wu (70890)

“…For other parameters (soil pH and EC), shelterbelt-influences were mainly observed in surface soils, e.g., EC was 14.7% lower in shelterbelt plantations than that in farmlands in the 0–20 cm layer, about 2.5–3.5-fold higher than 60–100 cm soil inclusion. …”

Data_Sheet_1_Shelterbelt Poplar Forests Induced Soil Changes in Deep Soil Profiles and Climates Contributed Their Inter-site Variations in Dryland Regions, Northeastern China.pdf by Yan Wu (70890)

“…For other parameters (soil pH and EC), shelterbelt-influences were mainly observed in surface soils, e.g., EC was 14.7% lower in shelterbelt plantations than that in farmlands in the 0–20 cm layer, about 2.5–3.5-fold higher than 60–100 cm soil inclusion. …”

Localization of LMNB1 during TGC formation. by Hiromu Morimoto (11133531)

“…The amount of LMNB1 protein peaked at day 3 and then gradually decreased. The data are represented as means ± SE (n = 5). …”

Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx by Ke He (331344)

“…The percent error between ME and the power-law equation was smaller than 5%, which means that there is no need to use the power-law equation to describe the relationship between A and LW. …”

Colony formation assay. by Vincent E. Baldanza (8781671)

“…<p>(A) Abrams, D-17, and HMPOS canine OSA cell lines treated with vehicle control (DMSO), 33% of the respective determined IC₅₀ dose of vismodegib (10 μM for Abrams and HMPOS; 15 μM for D-17), 66% of the respective determined IC₅₀ dose of vismodegib (20 μM for Abrams and HMPOS; 30 μM for D-17), and the full determined IC₅₀ dose of vismodegib (30 μM for Abrams and HMPOS; 45 μM for D-17). …”

Table_1_Synergistic Effects of Ocean Warming and Cyanide Poisoning in an Ornamental Tropical Reef Fish.docx by Diana Madeira (8772221)

“…However, when the most resistant size-class was concomitantly exposed to a sub-lethal dosage of cyanide (25 mg L^–1 instead of 50 mg L^–1) and ocean warming scenarios for 2100 (+3°C and heat wave +6°C), survival rates (%) decreased to 60 and 20%, respectively, and recovery times increased in the worst case scenario. …”

Different order of combined exercises: acute effects on 24-hour blood pressure in young men by Rafaello Pinheiro MAZZOCCANTE (10413590)

“…The DBP was lower at 4-5 h (-14.0 mmHg) in RA compared with CO. After performing RA exercises, there were greater decreases in BP during 24 h in young adults.…”

Relationship between rolling resistance, preferred speed, and manual wheelchair propulsion mechanics in non-disabled adults by Hunter Soleymani (16666614)

Data_Sheet_1_Aberrant amplitude of low-frequency fluctuations in different frequency bands and changes after one-night positive airway pressure treatment in severe obstructive slee... by Yuanfeng Sun (13277133)

“…In slow-4 frequency, there was significantly decreased ALFF in the right inferior temporal gyrus, and significantly increased ALFF in the left precuneus, right posterior cingulate gyrus and right median cingulate besides the slow-5 difference band showed. …”

Zinc gene silencing efficiency. by Alexandros Belavilas-Trovas (13301004)

“…Whole mosquitoes were collected and pooled at three time-points (3-, 7- and 10-days) post-dsRNA injection. 3–5 biological replicates were performed for each Zinc and the average expression of GFP dsRNA treated replicates was set as 1 and the decreased dsZinc replicates, compared to GFP dsRNA, was measured. …”

Methods of acquiring research EEG data from the clinical stream. by Lisa Yamada (18824166)

“…<p>The five stages for clinical iEEG acquisition are shown with different branching points for collecting research data. …”

Supplemental Material for Humphrey et al., 2020 by Kristen Humphrey (6788961)

Transient ERK1/2 dephosphorylation induces dissociation of Jarid2 and Ring1B and chromatin decompaction in NMP-L cells at the <i>PAX6</i> locus but does not reduce H3K27me3 nor eli... by Claudia I. Semprich (14204821)

“…Interprobe distance measurements in >50 nuclei in the three conditions in three individual experiments (<i>n</i> = > 150 nuclei/cell type, Mann–Whitney test/rank-sum test, *** <i>p</i> ≤ 0.001) (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000221#pbio.3000221.s024" target="_blank">S10 Data</a>), this decompaction correlated with a 2.5-fold decrease in number of base pairs per nm compared to both controls (untreated NMP-L (D3): 205 bp/nm, DMSO NMP-L (D3): 218 bp/nm and MEKi NMPL (D3): 87 bp/nm). …”