DataSheet1_A phase 1 study of dimdazenil to evaluate the pharmacokinetics, food effect and safety in Chinese healthy subjects.pdf by Fei Wang (19534)

“…The median T_max for dimdazenil was in the range of 0.5–1.5 h, and the apparent terminal t_1/2z ranged from 3.50 to 4.32 h. Taking Dimdazenil with food may delay T_max and decrease C_max, without affecting the total exposure (AUC). …”

Table_2_Functional analysis of the bZIP-type transcription factors AtfA and AtfB in Aspergillus nidulans.DOC by Beatrix Kocsis (13825417)

“…Production of the mycotoxin sterigmatocystin (ST) was decreased to undetectable levels in the ΔatfA mutant, yet ST production was restored in the ΔatfAΔatfB mutant, suggesting that ΔatfB can suppress ST production defect caused by ΔatfA. …”

Table_1_Functional analysis of the bZIP-type transcription factors AtfA and AtfB in Aspergillus nidulans.DOC by Beatrix Kocsis (13825417)

“…Production of the mycotoxin sterigmatocystin (ST) was decreased to undetectable levels in the ΔatfA mutant, yet ST production was restored in the ΔatfAΔatfB mutant, suggesting that ΔatfB can suppress ST production defect caused by ΔatfA. …”

Image_1_Functional analysis of the bZIP-type transcription factors AtfA and AtfB in Aspergillus nidulans.JPEG by Beatrix Kocsis (13825417)

“…Production of the mycotoxin sterigmatocystin (ST) was decreased to undetectable levels in the ΔatfA mutant, yet ST production was restored in the ΔatfAΔatfB mutant, suggesting that ΔatfB can suppress ST production defect caused by ΔatfA. …”

Retinoic acid regulates Bcl-2 family protein interactions in MCAO animals. by Ju-Bin Kang (16021324)

“…Molecular weights (kDa) are depicted at right. Data (<i>n</i> = 5) are represented as mean ± S.E.M. *<i>p</i> < 0.001, **<i>p</i> < 0.01 vs. vehicle + sham animals, #<i>p</i> < 0.01 vs. vehicle + MCAO animals.…”

Table_1_Examining the relationship between CDAI and frailty and its manifestation in Parkinson’s disease: a cross-sectional study.DOCX by Zhaohao Zeng (16989468)

“…Vitamin A, C, E, selenium and carotenoids exhibited J-shaped relationships where frailty risk decreased below intake thresholds of 1093.04 μg, 161.53 mg, 13.66 mg, 109.99 μg, and 5057.50 μg, respectively. …”

Presentation_1_Regional citrate anticoagulation for replacement therapy in patients with liver failure: A systematic review and meta-analysis.zip by Bo Peng (273834)

Table_1_The hemodynamic stability of remimazolam compared with propofol in patients undergoing endoscopic submucosal dissection: A randomized trial.docx by Yuwei Qiu (7455965)

“…</p>Results<p>The incidence of hypotension decreased by 50%, from 67.9% in propofol group to 32.1% in remimazolam group (p < 0.01). …”

Table_1_The gut microbiota as a potential biomarker for methamphetamine use disorder: evidence from two independent datasets.docx by Linzi Liu (9386378)

“…Background<p>Methamphetamine use disorder (MUD) poses a considerable public health threat, and its identification remains challenging due to the subjective nature of the current diagnostic system that relies on self-reported symptoms. …”

Data Sheet 1_Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.docx by Jingang Zhao (20416198)

“…Importantly, our vaccine provided complete protection for all six guinea pigs against a lethal challenge of 100 GPID₅₀, with histopathological scores indicating protection equivalent to that conferred by the inactivated vaccine. …”

Impact of land use land cover changes on ecosystem service value – A case study of Guangdong, Hong Kong, and Macao in South China by Sarah Hasan (8690172)

Image_1_Vitamin D Enhances Anticancer Properties of Cediranib, a VEGFR Inhibitor, by Modulation of VEGFR2 Expression in Melanoma Cells.pdf by Anna Piotrowska (802338)

Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration by Jeanette M. Metzger (8259900)

“…<div><p>Cardiac dysautonomia is a common nonmotor symptom of Parkinson’s disease (PD) associated with loss of sympathetic innervation to the heart and decreased plasma catecholamines. …”

<i>Pax2.1</i> and <i>pax6a</i> expression is altered in <i>sox11</i> morphants. by Lakshmi Pillai-Kastoori (596161)

“…Relative transcript abundance was normalized to <i>atp5h</i> (18 hpf) or <i>gapdh</i> (24 hpf) levels and is presented as the mean fold-change in expression relative to controls (n = 50 embryos per group, 3 independent biological replicates. …”

Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice by Sayantani Sinha (716150)

“…Surprisingly, it is not known whether such tumors also form in endochondral elements of the craniofacial skeleton. Here, we carried out a retrospective analysis of cervical spine MRI and CT scans from 50 consecutive HME patients that included cranial skeletal images. …”

Table1_Risk of drug-induced angioedema: a pharmacovigilance study of FDA adverse event reporting system database.xlsx by Maoxia Fan (16914033)

“…Based on the individual drug reporting odds ratio (95% confidence interval) as a measure of risk signal strength, the top five drugs are as follows: lisinopril [ROR (95% CI): 46.43 (42.59–50.62)], enalapril [ROR (95% CI): 43.51 (39.88–47.46)], perindopril [ROR (95% CI): 31.17 (27.5–35.32)], alteplase [ROR (95% CI): 29.3 (26.95–31.85)], ramipril [ROR (95% CI): 20.93 (19.66–22.28)]. …”

Image_1_Negative Association of Interleukin-33 Plasma Levels and Schistosomiasis Infection in a Site of Polyparasitism in Rural Cameroon.TIF by Severin Donald Kamdem (8069741)

“…</p><p>Principal findings: We found a prevalence of 13.5% (37/275), 18.2% (50/275), and 8% (22/275), respectively for schistosomiasis, malaria and hepatitis (B or C) single infections. …”

Image_1_Crop coefficient determination and evapotranspiration estimation of watermelon under water deficit in a cold and arid environment.jpeg by Hengjia Zhang (16381497)

“…<p>To investigate the evapotranspiration and crop coefficient of oasis watermelon under water deficit (WD), mild (60%–70% field capacity, FC)and moderate (50%–60% FC) WD levels were set up at the various growth stages of watermelon, including seedling stage (SS), vine stage (VS), flowering and fruiting stage (FS), expansion stage (ES), and maturity stage (MS), with adequate water supply (70%–80% FC) during the growing season as a control. …”

DataSheet_1_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.docx by Ermeng Xiong (11176635)

“…Defective plasmablast formation caused by Ern1 deletion could not be rescued by the active, spliced form of XBP1 whose processing is dependent on and downstream of IRE1a, suggesting that in early plasma cell differentiation IRE1a acts independently of XBP1. …”

Table2_Risk of drug-induced angioedema: a pharmacovigilance study of FDA adverse event reporting system database.xlsx by Maoxia Fan (16914033)

“…Based on the individual drug reporting odds ratio (95% confidence interval) as a measure of risk signal strength, the top five drugs are as follows: lisinopril [ROR (95% CI): 46.43 (42.59–50.62)], enalapril [ROR (95% CI): 43.51 (39.88–47.46)], perindopril [ROR (95% CI): 31.17 (27.5–35.32)], alteplase [ROR (95% CI): 29.3 (26.95–31.85)], ramipril [ROR (95% CI): 20.93 (19.66–22.28)]. …”