PRSS56 activity is required during both the vision-independent and dependent stages of ocular growth. by Seyyedhassan Paylakhi (4951933)

“…Reduced ocular axial length was associated with a significant decrease in VCD in <i>Prss56</i>^<i>F/F</i><i>; Ubc-Cre</i>^<i>ERT2</i> mice compared to <i>Prss56</i>^<i>F/+</i><i>; Ubc-Cre</i>^<i>ERT2</i> and uninjected controls at P30 and P45, N = 5 to 10 per group (<b>G</b>). …”

Spiking activity of dentate gyrus granule cells during exploratory behaviour evokes large short-term plasticity at mossy fiber synapses <i>in vitro</i>. by Anja Gundlfinger (366062)

“…A large dynamic range of response amplitudes is apparent with amplitudes generally largest with ISIs ranging from 50–1000 ms. …”

Alpha band EEG coherence in healthy nonagenarians by Mario Silva Jorge (12685567)

Antihypertensive effect and the underlying mechanisms of action of phytolaccagenin in rat models by Imran Ul Haq (12676309)

“…</p> <p>The antihypertensive effect of phytolaccagenin is due to a decrease in vascular resistance and cardiac depressant effects. …”

Evolutionary assembly drives community complexity. by Gui Araujo (22170819)

“…Mixed scenarios, with 20%, 50%, and 80% of invasion, exhibit a generally proportional decrease in values of richness from pure evolution to pure invasion. …”

Characterization of CLU-isoform biogenesis. by Hans Prochnow (461311)

“…(B) Western blots of recombinant CLU-V5 proteins in lysates (upper panel) and culture media (lower panel) of HEK-293 cells transiently expressing unmodified or point-mutated (crossed out codons) CLU cDNA variant 1. …”

Effect of charge-associated amino acid mutations on the surface charge of NDV HN protein and viral thermostability. by Yu Shang (49702)

“…(B) Scatter diagram summarizes the relationship between the charge of HN protein and viral thermostability (Time for 90% infectivity loss, min) at 56°C. Each point represents the data from one NDV mutant. (C) Molecular surfaces of mutated HN proteins are colored according to electrostatic potentials with a range of red (- 5.0 V) to blue (+ 5.0 V). …”

Bcl-xL siRNA effectively knocks down Bcl-xL mRNA and protein and induces platelet apoptosis. by Shifang Yu (721211)

“…<p>Leukocyte-depleted apheresis platelets (LDPs) were transfected with siBcl-xL or negative control siRNA (siNC) at a final concentration of 50 nM. LDPs without transfection were used as blank controls (control). …”

CRT silencing improved FZD-induced injury of mitochondria and cardiomyocytes. by Ming Zhang (9736)

“…When transfected NRCMs were stimulated with 50 µM FZD for 24 h, real-time PCR revealed that CRT silencing significantly inhibited the decrease of MnSOD mRNA expression (E), and western blot was used to determine the protein levels of CRT, phosphorylated and total STAT3, and MnSOD in the whole cell lysates. β-actin was used as a loading control. …”

Erratum: Why Do the Clients of Georgian Needle Exchange Programmes Inject Buprenorphine? by Otiashvili D. (4271656)

“…<i>Results:</i> Pharmaceutical buprenorphine in the form of Subutex® was the most commonly injected drug in terms of lifetime (95.5%) and last-month (75%) prevalence of use. 48% of those study participants who had injected Subutex at some point reported having used it to cope with withdrawal or to give up other opioids. 90.5% of Subutex injectors used 1–2 mg as a single dose, and the mean frequency of its injection was 6 times per month. 75% of Subutex injectors had used 3 or more types of illegal drugs during the last 30 days. …”

Reduced willingness to participate in large events. by Alyssa H. Sinclair (17102689)

“…Change in willingness was rated on a 5-point Likert-style scale. A) Mean change in willingness by event size. …”

Polyclonal HSV-2 IgG antibody response elicited by HSV-2 0ΔNLS, gD-2, or control immunogens. by William P. Halford (202208)

“…The titer of each serum sample was considered to be the reciprocal of the largest serum dilution that reduced HSV-2's cytopathic effect in Vero cell monolayers by at least 50%. (<b>B</b>) Representative immunofluorescent labeling of fixed HSV-2 plaques with a 1∶5,000 dilution of Day 60 serum from each immunization group. …”

PGRN knockdown results in reduced motor axon outgrowth. by Angela S. Laird (360986)

“…<p>A) Knockdown of <i>grna</i>, by morpholino targeted to both the start codon (ATG) and 5′UTR region of zebrafish PGRN sequence, produced a dose dependent decrease in axonal length compared to mismatch Control MO injected embryos.…”

The influence of the abdominal body segments on NMJ features. by Bonnie Nijhof (478491)

“…<p>The plots display the mean (dot) and 95% confidence interval (blue error bars) of the NMJ values for each feature over the abdominal body segments A2 (n = 148), A3 (n = 356), A4 (n = 399) and A5 (n = 198). …”

The sensitivity analysis. by Cheol Yong Han (9596787)

“…The sensitivity index − 0.5 means that a 1% increase of a parameter value <i>x</i> will result in the 0.5% decrease of the variable <i>y</i>.…”

Factor analysis of abnormal postural change cardiovascular autonomic indices within pSS patients by Fin ZJ Cai (51289)

“…RR intervals, low frequency RR power (HRV), proportion of successive RR intervals differing by more than 50 ms (pNN50), change in systolic blood pressure on standing (ΔSBP), low frequency systolic blood pressure power (BPV) and the 30/15 ratio were all decreased in patients who have primary Sjögren's syndrome (pSS) relative to control individuals on standing. …”

Vascular permeability visualized via FITC-dextran staining. by Steven Hyun Seung Lee (12884158)

“…Data represented as mean ± SEM (n = 5).</p>…”

Changes in work output, redox state of mitochondrial respiratory chain, oxygen consumption, and heart rate of isolated perfused hearts from wild type and <i>Mecr</i> transgenic mic... by Zhijun Chen (254277)

“…<p>From the 25 min time point, the hearts were electrically paced to 5 Hz and from the 30 min time point they were paced to 7.5 Hz. …”

Table 1_Atherosclerosis index and BMI: new predictors of cognitive function in ischemic survivors.docx by Lingyan Zhao (13985310)

“…Each one-unit increase in AIP was associated with a 1.15-point reduction in MMSE score (p < 0.001). Similarly, each one-unit increase in AIP-BMI corresponded to a 0.04-point decrease in MMSE score (p < 0.001). …”

Characterisation of antigens bound by MAbs CA7 and TH1. by Genna E. Davies (505256)

“…Asterisks show significant (p<0.001) decrease in absorbance value compared to respective controls (time point zero). …”