Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells and in xenografts: Identification of apoptotic genes as targets for demethylation-2 by Khaldoun Al-Romaih (79731)

“…</p><p></p>n is the Mean of tumor volumes measured in 12 xenograft tumors. There was a significant decrease (p < 0.05) in tumor volumes as a result of decitabine treatment. , Osteoid assessment . …”

PLK2i treatment of OHSCs does not affect generation of pS129 positive aggregates, but reduces the nuclear pS129 intensity. by Sara Elfarrash (8159490)

“…Slices were stained with MJF-14, pS129 (11A5), and DAPI, scale bar = 50 μm. i. The magnified region (white boxed area) shows nuclear pS129-signal that co-localizes with DAPI (arrowheads). ii. …”

microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model by Fu Jia Liu (422650)

“…Interestingly, miR-206, -290, -291a-5p and -30c-1*, positively correlated with the infarct sizes, with an initial increase up to 24hrs followed by a gradual decrease from 48 hrs to 168 hrs (R = 0.95). …”

Developmental differences in global cortical phase-locking and power. by Scott Marek (841529)

“…<p>(A) Across most frequency bands, adolescents displayed similar resting-state phase-locking to adults. However, in the 5–9 Hz frequency band, there was a significant linear decrease in phase-locking throughout development (gray shaded region; <i>p</i> < 0.05, FDR corrected). …”

Smad1 target genes repressed and activated in senescence. by Atsushi Kaneda (198186)

“…<p>(<i>A</i>) Repression of Smad1 target genes by H3K27me3. 838 Smad1 target genes in MEF were sorted by fold expression change between MEFp2 and mean of RasV12 day3, 7, and 10 (<i>Expression column</i>). 50 genes showed increase of H3K27me3 reads in RasV12 by 0.4 or more (↑<i>column</i>), and were significantly enriched downward (*P = 0.004, Kolmogorov-Smirnov test), i.e. repressed. …”

Buffer Zones for 2,4-D Applications Nearby Tobacco Fields by Matheus Machado Noguera (13022509)

“…Drifted herbicide was collected using tobacco plants placed at various points (-50 up to 400 meters from application zone), following three schemes: a) 0 to 0.5 hours after application (HAT); b) 0 to 24 HAT; and c) 0.5 to 24 HAT. …”

Interim report on the effective intraperitoneal therapy of insulin-dependent diabetes mellitus in pet dogs using “Neo-Islets,” aggregates of adipose stem and pancreatic islet cells... by Anna Gooch (7406363)

“…Current results from this translational study indicate that in dogs, Neo-Islets appear to engraft, redifferentiate and physiologically produce insulin, and are rejected by neither auto- nor allo-immune responses, as evidenced by (a) an absent IgG response to the allogeneic cells contained in the administered Neo-Islets, and (b) progressively improved glycemic control that achieves up to a 50% reduction in daily insulin needs paralleled by a statistically significant decrease in serum glucose concentrations. …”

Reduced (owner-animal metadata) XGBoost model on the <i>any health problem</i> binary using the primary decision-maker dataset. by Richard Barrett-Jolley (739341)

“…The fact that the prediction thresholds are all low (< 0.5) shows that this model struggles to predict health issues. …”

Acute HIV-1 gp120 induces calcium (Ca²⁺) flux and dephosphorylation of Kv2.1 in hippocampal neurons. by Andrew J. Shepherd (462677)

“…In the left panel, HH buffer (wash) was perfused over the coverslip, prior to a pulse of 50 mM KCl (K50) to demonstrate depolarization-induced Ca²⁺ influx in each neuron. …”

Acute TTBK1 inhibition reduces tau phosphorylation at disease relevant sites <i>in vivo</i>. by Gregory M. Dillon (8681430)

“…(A) At the highest dose tested (75mg/kg), there was a significant decrease in tau phosphorylation at several sites when quantified by immunoblotting (S422, AT180, S396, and AT8). …”

Slow killing strains survive better in small spaces with equal starting abundance. by Raymond Copeland (17854736)

“…Each line consists of 20 evenly spaced data points. Each data point is the mean of many simulations; for the <i>N</i>_<i>max</i> = 9, 26, 68, 106, 1025, and 10,686 cell simulations we average across 750, 750, 500, 100, 50 and 20 simulations, respectively. …”

DataSheet_1_Noninvasive Analysis of Tree Stems by Electrical Resistivity Tomography: Unraveling the Effects of Temperature, Water Status, and Electrode Installation.pdf by Andrea Ganthaler (7860380)

“…Temperature changes above the freezing point did not affect ER distribution patterns but average ER levels, which increased exponentially and about 2.5-fold from 30 to 0°C in all species. …”

PPARγ-mediated transactivation activity as well as receptor binding activity of falcarindiol. by Atanas G. Atanasov (27419)

“…Each data point represents the mean ± SEM from four independent experiments performed in duplicate.…”

Action potential amplitude and shape vary with firing rate for the majority of neurons. A by Peter Stratton (158746)

“…<b>B</b>: Rise-time, fall-time and half-width changes for all neurons. Mean changes were respectively +4.6±9.0% (p<0.007), +0.8±9.3% (p>0.64) and +5.2±7.9% (p<0.0008). …”

Influential genomes and their combined effect. by Eva S. Deutekom (7321661)

“…Genomes that are not selected have a white fill. The colour of the scatter plot points is according to the cosine distance to human, with a maximum cosine distance found to be 0.57. …”

Data_Sheet_1_Implementation of Video Visits During COVID-19: Lessons Learned From a Primary Care Practice in New York City.pdf by Sanjai Sinha (256132)

“…Patients who completed video visits reported high satisfaction (mean 4.6 on a 5-point scale [SD: 0.97]); 13.3% reported technical challenges during video visits.…”

Relationship between cluster extension and HCV RNA content. by Frederik Graw (175938)

“…Symbols indicate the mean of total HCV RNA content and cluster size, arrows determine the 2.5% and 97.5% percentiles of the 10,000 bootstrap replicates. …”

TBr inhibited cell proliferation in leukemia cell lines. by Anup S. Pathania (657368)

“…<p>(A–B) Cell proliferation assay. Cells were treated with 1, 10, 30, 50 and 100 µM concentrations of TBr for 24 and 48 h. …”

DataSheet1_Arctic stratosphere changes in the 21st century in the Earth system model SOCOLv4.pdf by Pavel Vargin (16809465)

“…In the late 21st century, the strengthening of the zonal mean meridional heat flux with a maximum of up to 20 K m/s (∼25%) in the upper stratosphere close to 70°N in January–February is obtained in the moderate scenario of GHG emission, while only a slight increase in this parameter over 50 N–60 N with the maximum up to 5 K m/s in the upper stratosphere and a decrease with the comparable values over the high latitudes is revealed in the severe GHG emission scenario. …”

Fig S1. by Leonardo Santos (477304)

“…<p>Testing of gRNA Efficiency in Inducible 3T3-Cas9 Cells. (A) Western blot analysis of total cell extracts at various time points following incubation with doxycycline. …”