Data_Sheet_2_Global Burden Attributable to High Low-Density Lipoprotein-Cholesterol From 1990 to 2019.docx by Heyue Du (11229207)

“…The absolute annual burden from deaths and DALYs attributed to high LDL-C increased by 46% (95% UI, 35–56%) and 41% (95% UI, 31–50%) from 1990 to 2019. The age-standardized SEV, death, and DALY was decreased by 9% (95% UI, −11 to −8%), 37% (95% UI, −41−33%), and 32% (95% UI, −37 to −28%), respectively, during the study period. …”

Effect of the two mind-sets induction on the nociceptive S2-ER% oscillatory activity at Cz. by Elia Valentini (658405)

“…The difference peaked at 262 ms (range: 239–290 ms) and 5 Hz (3.3–6.8 Hz).</p>…”

Evaporative cooling system for gestating and lactating sows: a systematic review by Melissa Fabíola dos Santos Alves Mendes (10441260)

“…It can be concluded that the use of evaporative cooling system promotes increase in feed intake per lactating sow, decrease in weight loss in lactation, increase of weight of piglets at weaning, temperature reduction of the barns and decrease of the respiratory rate of the sows. …”

Table 1_Dupilumab relieves pruritus both in uremic pruritus and in atopic dermatitis with chronic kidney disease: a retrospective real-world study.docx by Qian Wang (32718)

“…The percentages of UP patients who achieved PP-NRS ≥ 4-point improvement and 5D-IS ≤ 10-point at week 4, 12, and 16 did not significantly differ from those of AD patients with CKD (p > 0.05). …”

Astrocytic volume changes in the cortex of GFAP/EGFP and GFAP/EGFP/α-Syn^−/− mice during hyperosmotic stress. by Miroslava Anderova (155561)

High-Throughput Screening of Australian Marine Organism Extracts for Bioactive Molecules Affecting the Cellular Storage of Neutral Lipids by James Rae (210551)

“…The activity of heterofibrin A1 was dose dependent with 20 µM inhibiting LD formation and triglyceride accumulation by ∼50% in the presence of 50 µM oleic acid. …”

Hit expansion around chloroxine. by Sam Barker (4832121)

“…This modification causes a significant decrease in this compound’s activity as a co-treatment with ceftazidime, with a <i>p</i>IC50 ≈ 3.4. 5,7-dichloro-2-methyl-8-quinolinol differs from chloroxine by addition of a methyl group in the 2-position (B). …”

Activation of kinin B₁R in the acute disease phase improved the pathology of EAE. by Rafael C. Dutra (205755)

“…The animals were separated into different groups: naive group, EAE group, mice treated with the B₁R agonist DABK (300 nmol/kg, i.p.) and mice treated with the B₁R antagonist DALBK (50 nmol/kg, i.p.). The agonists/antagonists were administered intraperitoneally (i.p.), twice a day (12/12 h), during different time-points of EAE. …”

Effect of BC-819 on cell growth in different lung cancer cell lines. by Günther Hasenpusch (350166)

“…The influence of BC-819 on bioluminescent A549-C8-luc was examined as well and revealed decreased luciferase and therefore reduced cell growth (more than 50%) as early as after 24 hours (C). …”

Dissociation, and not specific actions of Trypsin-EDTA, acts to suppress neurectoderm formation. by James N. Hughes (319868)

“…Error bars represent sem. (a) denotes a decrease compared to MEDII⁻/Dissociation⁻ where p<0.01. …”

Long-term growth curves of nucleus pulposus chondrocytes (NPCs) obtained from donors of various ages. by Jun-Seok Lee (181420)

“…<p>Plots of cumulative population doubling levels (PDLs) against time in culture (A) and passage number (B). The cumulative PDLs of NPCs from the young group (patients in their 30s, 40s, and 50s) were relatively higher than those from the old group (patients in their 60s and 70s). …”

The reduced expression of ZBRK1 is inversely correlated with the increased expression of KAP1 in cervical cancer specimens. by Li-Fang Lin (449199)

“…<p><b>A</b>, All tumor specimens from 50 patients with different stages of cervical cancer were obtained from surgically resected tissues. …”

High Intensity Exercise in Multiple Sclerosis: Effects on Muscle Contractile Characteristics and Exercise Capacity, a Randomised Controlled Trial by Inez Wens (635807)

“…</p><p>Results</p><p>Compared to SED, 12 weeks of high intensity exercise increased mean fiber CSA (H_ITR: +21±7%, H_CTR: +23±5%). …”

Table 1_Imeglimin may affect hemoglobin A1c accuracy via prolongation of erythrocyte lifespan in patients with type 2 diabetes mellitus: insights from the INFINITY clinical trial.d... by Takeshi Osonoi (1951555)

“…</p>Results<p>The change in hemoglobin concentration at 6 months was not statistically significant (mean ± SD: −0.2 ± 0.9 g/dL; p = 0.23). While HbA1c and GA decreased and 1,5-AG increased one month after imeglimin initiation, GA and 1,5-AG showed rapid changes compared to the gradual decrease in HbA1c. …”

Inhibition of PI3K/Akt activity reduces phosphorylation of GSK3β while increases HB9 motor neuron differentiation. by Luis Ojeda (208583)

“…In both ELL and FL primed groups, all inhibitors decreased GSK3β Ser9 phosphorylation as compared with DMSO controls (mean ± SEM; n = 3; * p<0.05, ** p<0.01, *** p<0.001, one-way ANOVA). …”

“Deep” Sequencing Accuracy and Reproducibility Using Roche/454 Technology for Inferring Co-Receptor Usage in HIV-1 by David J. H. F. Knapp (444976)

“…For repeated measurements of a non-homogeneous clinical sample, increasing input copy number both decreased variance in the measured proportion of non-R5 using virus (p<<0.001 and 0.02 for single replicates and triplicates respectively) and increased measured viral diversity (p<0.001; multiple measures). …”

Training at maximal power in resisted sprinting: Optimal load determination methodology and pilot results in team sport athletes by Matt R. Cross (5089268)

“…<div><p>Aims</p><p>In the current study we investigated the effects of resisted sprint training on sprinting performance and underlying mechanical parameters (force-velocity-power profile) based on two different training protocols: (i) loads that represented maximum power output (<i>L</i>_opt) and a 50% decrease in maximum unresisted sprinting velocity and (ii) lighter loads that represented a 10% decrease in maximum unresisted sprinting velocity, as drawn from previous research (<i>L</i>₁₀).…”

DataSheet1_Interaction of Serum Alkaline Phosphatase and Folic Acid Treatment on Chronic Kidney Disease Progression in Treated Hypertensive Adults.docx by Yuanyuan Zhang (101797)

“…The primary outcome was CKD progression, defined as a decrease in estimated glomerular filtration rate (eGFR) of ≥30% and to a level of <60 ml/min/1.73 m² if baseline eGFR was ≥60 ml/min/1.73 m²; or a decrease in eGFR of ≥50% if baseline eGFR was <60 ml/min/1.73 m²; or end-stage renal disease. …”

Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments by Céline Portal (3876436)

“…Ten days of BAK in one eye followed by 4 days without any treatment induced a −18.3% decrease in conjunctival goblet cell density. …”

Difference in GHG emissions (<em>x</em>-axis) and food availability (<em>y</em>-axis) in 2050 for the different scenarios with respect to 'TREND' by H Valin (557174)

“…</strong> Difference in GHG emissions (<em>x</em>-axis) and food availability (<em>y</em>-axis) in 2050 for the different scenarios with respect to 'TREND'. Panels (A)–(C) and (D) delineate domains where food provision increases ((A), (B)) or decreases ((C), (D)) and GHG emission savings increase ((B), (D)) or decrease ((A), (C)). …”