GCS in hypothalamic neurons regulates neuronal leptin signaling at the plasma membrane. by Viola Nordström (388258)

“…<p>(A) Stat3 phosphorylation was markedly decreased in Arc sections of <i>Ugcg</i>^{f/f//CamKCreERT2} mice in response to peripheral leptin (5 mg/kg; 45 min) 6 wk p.i. …”

Global correspondence of gene expression between human psoriasis and mouse psoriasiform phenotypes. by William R. Swindell (175427)

“…The Pearson correlation coefficient (<i>r</i>) calculated from each scatterplot is shown in the lower-right corner of (A) - (F). In panel (G), the human-mouse correspondence was evaluated with respect to a subset of 2617 transcripts elevated in human psoriasis and 3540 transcripts decreased in human psoriasis (FDR-adjusted P<0.05, log₂-transformed fold-change estimate greater than 0.50 in absolute value). …”

Subfoveal choroidal thickness and retinal nerve fiber layer alterations in chronic heart failure patients by Hatice Selen Kanar (12678636)

“…The patients were categorized into 2 groups: group 1: patients with 30-50% left ventricle ejection fraction and group 2: patients with the corresponding fraction value of <30%. …”

Quantitative analysis <i>in vivo</i> MRI scans. by Lucas W. E. Starmans (379995)

“…<p><i>In vivo</i> T₂ of the thrombus pre- and post-injection with FibPep-ION-Micelles (n = 5) and NCFibPep-ION-Micelles (n = 4). The horizontal lines represent the group means and the average mean for the two groups combined (n = 9). …”

Augmentation of autophagy with rapamycin protects against tumor metastasis. by Jun Yan (28467)

“…Data are presented as the mean ± S.E. of 5 mice per group. (C) Rapamycin treatment decreases p62 accumulation in the lung tissue. …”

Navigational performance and reward checking during the auditory and visual virtual spatial navigation tasks. by Jesse D. Cushman (479673)

“…Two way ANOVA for effect target vs. other quadrants and auditory vs. visual trial types: Effect of quadrant F(1,8)  = 95.16, p< 0.001, Effect of task type: F(1,8)  = 2.08, p<0.001, Interaction of quadrant and task type: F(1,8)  = 2.08, p = 0.002; Effect of quadrant for auditory task: p = 0.097, target quadrant percentage occupancy: 23.9±0.5% vs. mean non-target occupancy: 25.36±0.17%, note that occupancy is slightly decreased in the target quadrant as animals entering the reward zone are teleported out; for visual task: p<0.001, target quadrant percentage occupancy: 59.6±1.15% vs. mean non-target occupancy: 13.5±0.38%, N = 5. …”

Effects of omega-6/3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats by Francisco Edson Ximenes Gomes Pereira (6675698)

“…Fertility was evaluated by counting the number of embryos in the left hemi-uterus. Results: The mean number of writhings was as follows: sham-operated, 11.1 ± 2.9; control with endometriosis, 49.3 ± 4.4; omega-6/3, 31.5 ± 2.7; omega-9/6, 34.1 ± 4.5; medroxyprogesterone acetate, 2.1 ± 0.8; meloxicam, 1 ± 0.3. …”

Expression of miR-202-3p and its target Sufu mRNA in CLL cells. by Mosavar Farahani (819379)

“…The results represent the findings of three independent experiments. <b>(B)</b> HS-5 cells incubated with MEC-1 exosomes for 24 hrs show decreased expression of Sufu, one of the miR-202-3p targets, by RT-qPCR analysis. …”

Automated gait analysis reveals early signs of motor defects in <i>Mecp2^stop/y</i> mice. by Kamal K. E. Gadalla (659748)

“…(B–F) Plots showing stride length, overlap distance, stance width, step angle and gait symmetry (mean +/− SEM) measured in WT and <i>Mecp2^stop/y</i> mice at 4, 8 and 10 weeks (WT n = 7 at 4 weeks and 5 at 8 & 10 weeks; <i>Mecp2^stop/y</i> n = 6 at 4 weeks, n = 5 at weeks 8 & 10. …”

OSTEOTOMY AT THE BASE OF FEMORAL NECK AND OSTEOPLASTY FOR THE TREAMENT OF SCFE by LARISSA MARTINS GARCIA (14108288)

“…Methods: Comparative cohort with 12 patients (14 hips) with moderate and severe SCFE who underwent osteotomy at the base of neck and osteoplasty between 2007 and 2014. The mean age at surgery was 13.3 ± 2.5 years and the mean follow-up was 3.8 ± 2.2 years. …”

Validation of the Dual-path Platform chromatographic immunoassay (DPP® CVL rapid test) for the serodiagnosis of canine visceral leishmaniasis by Fabiano Borges Figueiredo (437925)

“…Analysis of the clinical groups showed a gradual decrease in the sensitivity and an increase in the specificity with the reduction of clinical signs in the dogs that were assessed, reaching a sensitivity of 75% (42.8-94.5%) among asymptomatic dogs and lower specificity of 56% (46.2-66.3%) among symptomatic dogs. …”

Early term ocular changes after cold compress application by Alperen Bahar (6571784)

“…Results: The average age of the participants was 30.74 ± 5.82 years. There was no significant change in the central corneal thickness after cold compress application, and there was a significant decrease in the anterior segment volume (p<0.001), anterior segment depth (p<0.001), and pupil diameter. …”

Marimastat reduces necroinflammatory injury following a single dose of carbon tetrachloride (CCl4) via a TNF-dependent pathway. by Vincent E. de Meijer (343377)

“…Serum ALT levels in TNF p55−/− p75−/− animals were 5-fold lower compared to wild type controls, corroborating the findings on histology and indicating decreased hepatic injury in animals lacking both TNF-receptors (F). …”

Effects of lesions and dropout on network information profiles. by Alexandra M. Proca (18721264)

“…By increasing redundancy, dropout (denoted as <i>p</i> = 0.0 and <i>p</i> = 0.5) results in decreased reliance on individual neurons, allowing the network to be more robust to their removal. …”

Levels of ghrelin and gastrin mRNA in remodeled stomach after VSG and RYGB. by Konstantinos Arapis (715018)

“…<b>(D)</b> Comparative number of gastrin positive cells per antral mucosa area (μm²) showing significant decrease in G cell number. Values are means ± SEM for n = 4 in each group.…”

Data_Sheet_1_Modulation of Septo-Hippocampal Neural Responses in Anesthetized and Behaving Rats by Septal AMPA Receptor Mechanisms.docx by Khairunisa Mohamad Ibrahim (10921080)

“…The current results showed that microinjection of AMPAR antagonist, NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione, 20 μg/μl, 0.5 μl), evoked a decrease in the frequency of theta activity evoked by various means in anesthetized and behaving rat. …”

Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice by N.F. Correa-Netto (6510125)

“…Animal models provide a relevant and accessible means of investigating the behavioral effects of ayahuasca without the environmental conditions associated with the ritualistic use of the beverage. …”

Table 2_Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.docx by Supriya Raghav (21412907)

“…Machine learning models, including random forest and K-means clustering, were used to identify key factors influencing treatment costs and to segment patient subgroups that were most responsive to the intervention. …”

Early term ocular changes after cold compress application by Alperen Bahar (6571784)

“…Results: The average age of the participants was 30.74 ± 5.82 years. There was no significant change in the central corneal thickness after cold compress application, and there was a significant decrease in the anterior segment volume (p<0.001), anterior segment depth (p<0.001), and pupil diameter. …”

Role of EZH2 and G9a enzymes in histone methylation pattern and in miR-212 expression levels in NSCLC. by Mariarosaria Incoronato (197260)

“…These results suggest that in Calu-1 cells the upregulation of EZH2 and G9a enzymes contributes to increase histone methylation and thus to decrease miR-212 expression levels. Means ± SD of four independent experiments in triplicate are given.…”