EGCG treatment decreases TTR deposition and associated biomarkers in the gastrointestinal tract of old hTTR V30M mice. by Nelson Ferreira (188837)

Statistical summary for weekly weather and air quality variables in state parks and protected areas (PPA) over the study period (2017 - 2021) in the Pacific Northwest, United State... by Kira Minehart (21029571)

Statistical summary for weekly weather and air quality variables in local parks and protected areas (PPA) over the study period (2017 - 2021) in the Pacific Northwest, United State... by Kira Minehart (21029571)

Statistical summary for weekly weather and air quality variables in federal parks and protected areas (PPA) over the study period (2017 - 2021) in the Pacific Northwest, United Sta... by Kira Minehart (21029571)

Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen. by Pranjali Beri (14945400)

“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”

Decreased expression of 5-HT_2A receptors but not of PSD-95 in spinal cord of carrageenan-injected rats. by Anne-Sophie Wattiez (460341)

Decreased <i>S</i>. <i>epidermidis</i> biofilm formation on immobilized proteins MBP-QQ-5 and MBP-QQ-7. by Nancy Weiland-Bräuer (5581526)

Mean SARS-CoV-2 viral load log 10 between groups. by Bruno Martins Tomazini (6509528)

“…</p><p>Results</p><p>From September 25, 2021, to February 3, 2022, 153 patients were randomized. The mean decay rate in SARS-CoV-2 viral load log₁₀ within 10 days was -3.75 (95% CI, -4.11; -3.19) in the placebo group, -3.83 (95% CI, -4.40; -2.27) in the halofuginone 0.5mg group and -4.13 (95% CI, -4.69; -3.57) in the halofuginone 1mg group, with no statistically significant difference in between placebo vs. halofuginone 0.5mg (mean difference -0.08; 95% CI -0.82 to 0.66, p = 0.96) and between placebo vs. halofuginone 1mg (mean difference -0.38; 95% CI, -1.11; 0.36, p = 0.41). …”

Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival. by Kyle C. Kloepping (9928265)

“…The error bars for all data presented in Fig 2 represent the mean ± SEM. Results demonstrate that TPP derivatives decrease melanoma cell viability and clonogenic survival; and there is a structure-activity relationship between TPP side chain length and decreased viability and clonogenic survival.…”

Geometric mean concentrations of 5 most abundant PCDD/F congeners and the sum of other congeners (A), and PCDD and PCDF TEQ (C) in different study areas during the first (1972–1986... by Matti Viluksela (321291)

Telmisartan decreased iNOS expression in LPS-induced BV2 microglia. by Nofar Torika (3169497)

LGP2 overexpression decreases the transcript levels of the IFN signaling and proinflammatory cytokines during ZIKV infection. by Zhongyuan Tan (5779016)

Effect of CXB and DMC combinations on ATP supply derived from both glycolysis <i>plus</i> OxPhos in HeLa (A) and SiHA (B) cells. by Diana Xochiquetzal Robledo-Cadena (5265959)

Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study by Jilles M. Fermont (3746068)

“…In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. …”

Committed effective doses calculated using five different sets of data. by Martin Šefl (11607984)

Nicotine decreased Akt phosphorylation in SK-BR-3 cells. by Masanori A. Murayama (5774585)

(A) Decreasing CaMKII activity by KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L) decreases spontaneous AP firing rate (n = 10 for each drug), cAMP (n = 4 for each drug) and ATP (n = 5 for each drug). by Yael Yaniv (162548)

Depletion of SAMHD1 induces cell cycle delay and spontaneous DNA damage response. by Kiwon Park (6492266)

Depletion of SAMHD1 induces R-loop-mediated genome instability and cellular DNA damage response. by Kiwon Park (6492266)

Functional analysis of miR-142-3p upregulation on invasiveness, viability and size of MDA-MB-231, MDA-MB-468 and MCF-7 breast cancer cells. by Alexander Schwickert (835514)

“…(f, h) pseudo-three-dimensional representations of the phase images in e, g correspond to the projection of the cell thickness. (i) cell volume V of n = 251 miR-142-3p transfected cells appears significantly decreased in comparison to the volume of n = 172 control cells; Data are mean ± SEM, *P<0.05, ***P<0.001.…”