Supplementary Material for: Polypharmacy and the Progression of Chronic Kidney Disease: Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease by Min H.K. (10922121)

“…Polypharmacy was defined as taking 6 or more medications at the time of enrollment; renal events were defined as a ≥50% decrease in kidney function from baseline values, doubling of the serum creatinine levels, or initiation of renal replacement treatment. …”

No inhibition of TrxR1 activity <i>in vitro</i> by addition of SecTRAPs by Karin Anestål (377878)

“…</p>b,<p>TrxR1 activity is given as turnover (min⁻¹) calculated from the decrease at 340 nm detected in a microplate reader assay with 5 nM TrxR1, 0.5 nM-500 nM truncated TrxR1 as SecTRAP, 10 µM Trx, 145 µM Insulin in 50 mM Tris-Cl, 2 mM EDTA, pH 7.4 and 200 µM NADPH.…”

Contribution of anti-MPER antibodies to the plasma's cross-neutralizing activities. by Iliyana Mikell (120166)

“…The Log10 decrease in IC50 neutralization titers in the presence of the MPER peptide is indicated.…”

Comparisons and correlations of pain intensity and respiratory and peripheral muscle strength in the pre- and postoperative periods of cardiac surgery by Thayse Campos de Menezes (6302564)

“…Methods: Forty-six patients were recruited, including 17 women and 29 men, with a mean age of 60.50 years (SD = 9.20). Myocardial revascularization surgery was performed in 36 patients, replacement of the aortic valve in 5 patients, and replacement of the mitral valve in 5 patients. …”

Data_Sheet_1_Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery.xlsx by Akihiro Kambara (10006775)

“…At 2 years post-operatively, they were able to maintain their preoperative level (22.6 ± 5.3). The patients were classified in to the cognitive decline group [11 (23%) patients; a decrease in the MMSE score by ≥ 2 points 2 years after surgery] and the maintenance/improvement group [37 (77%) patients]. …”

Interim report on the effective intraperitoneal therapy of insulin-dependent diabetes mellitus in pet dogs using “Neo-Islets,” aggregates of adipose stem and pancreatic islet cells... by Anna Gooch (7406363)

“…Current results from this translational study indicate that in dogs, Neo-Islets appear to engraft, redifferentiate and physiologically produce insulin, and are rejected by neither auto- nor allo-immune responses, as evidenced by (a) an absent IgG response to the allogeneic cells contained in the administered Neo-Islets, and (b) progressively improved glycemic control that achieves up to a 50% reduction in daily insulin needs paralleled by a statistically significant decrease in serum glucose concentrations. …”

TEA block of transient K current in rabbit CB chemoreceptor cells by Olaia Colinas (45959)

“…(A) Representative experiment showing the decrease in the peak current amplitude in depolarizing pulses to +40 mV upon application to the bath solution of TEA at concentrations from 10 M to 10 M as indicated. …”

Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma by Sigfus Gunnlaugsson (10358988)

“…Multivariable linear regression models revealed a significant sex interaction with PSQ on asthma control (<i>p</i> = 0.003), such that for each 0.10 point increase in PSQ there was a 1.88 point decrease in ACT score for females but only 0.21 point decrease in ACT score for males. …”

Table_1_Adipokinetic Hormone Receptor Mediates Trehalose Homeostasis to Promote Vitellogenin Uptake by Oocytes in Nilaparvata lugens.DOCX by Kai Lu (166354)

Table_2_Adipokinetic Hormone Receptor Mediates Trehalose Homeostasis to Promote Vitellogenin Uptake by Oocytes in Nilaparvata lugens.DOCX by Kai Lu (166354)

Mutation spectrum of eUCR41 in sample CC. by Anna De Grassi (62033)

“…Values corresponding to the middle point of each window are reported. Mutability increases with the decrease of sequence conservation: it is always below average for sequence identity >50%, whereas it is above average for nonconserved segments. …”

MK-2206 induced cytotoxicity, inhibited proliferation and was able to overcome the protective effects of the tumor microenvironment. by Vijay Ramakrishnan (117159)

“…<p>When we cultured MM cell lines with indicated concentrations of MK-2206 for 48 hrs we observed dose dependent decrease in <b>A)</b> viability as observed by MTT assays and <b>B)</b> tritiated thymidine uptake indicative of inhibition of proliferation albeit with differences in the sensitivity of cell lines to MK-2206. …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

The strength of the signal at binding sites depends on the free energy of repressor binding. by Rosalind Wenshan Pan (17174817)

“…Each data point is the mean of average mutual information across 20 synthetic datasets with the corresponding repressor binding energy. …”

microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model by Fu Jia Liu (422650)

“…Interestingly, miR-206, -290, -291a-5p and -30c-1*, positively correlated with the infarct sizes, with an initial increase up to 24hrs followed by a gradual decrease from 48 hrs to 168 hrs (R = 0.95). …”

Synaptotoxic PrP^Sc species are propagated from early in the evolution of M1000 prion disease. by Simote Totauhelotu Foliaki (5614364)

“…<p>(A) CA1 region LTP of WT mouse hippocampal slices was significantly disrupted following a five minute exposure to 0.5% (w/v; in artificial CSF) crude M1000 brain homogenates (cM1000) derived from M1000 infected WT Balb/c mice (infected through routine intracerebral injection [R.ic]) at 30% of the incubation period to the terminal stage of disease (TSD). …”

Graphene Oxide Grid Preparation by Thomas G. Martin (2619529)

“…Graphene-oxide is commercially available as solubilized flakes in sizes ranging from less than 0.5 µm to bigger than 50µm. This allows for a simple grid preparation in a few minutes without expensive equipment.…”

Measurement of threshold energies for optical pacing. by Matthew T. McPheeters (143584)

“…Error bars reflect the standard error (A) and standard deviation (B-D). In panels C and D, * indicates a statistically significance (p < 0.001) decrease compared to the smallest pulse width and spot size.…”

Validation of host-specific proteins involved in regulating Mtb infection. by Shilpi Jayaswal (250300)

“…In view of the inherent differences between the siRNA pools in the two screens, a 50% effect on bacterial load was employed as the cut-off for validation in the latter screen. …”

Improvement of the French voicing categorical perception in children with SLI after phonological auditory training by Gregory Collet (7422254)

“…With some difficulties at the beginning, children can progressively improve their performance on a task pointing specifically their difficulties with voicing. …”