Bortezomib inhibits infectious DENV production in primary monocytes. by Milly M. Choy (790882)

“…(E) Bortezomib also inhibited 50% of virus production of the attenuated strain of yellow fever virus, YF17D, at a concentration of 0.5 nM. …”

Local recurrent connectivity emerging from unsupervised learning improves reconstruction quality. by Boris Vladimirskiy (837542)

“…<p><b>a</b> Evolution of reconstruction error (<i>δ</i>, golden, averaged across 50 consecutive presentations) during 5000 random presentations from a set of 1000 training images. …”

RAGE blocking and APP inhibition synergistically reduce oxidative stress, apoptosis and rescue sequential gliocentric cell fate change in DS HNPs. by Jie Lu (139953)

“…(B) Graphs show the S100B stimulation for 24 hours dose dependently increase H₂O₂ production and decrease mitochondrial membrane potential which can be blocked by RAGE antibody (1 µg/ml) or dalteparin sodium (1 IU/ml) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022126#pone.0022126.s005" target="_blank">Figure S5A</a></b>). …”

Image_1_Innovative agroecological practices can restore degraded farmlands and revive crop yields.JPEG by Jules Ntamwira (9683561)

“…T3 (compared to T1), had a decrease in acidity and Al³⁺; an increase in soil organic matter, K+, Ca+, and aboveground carbon stock (26.5 t/ha against 5.6 t/ha). …”

Galectin-3 expression levels in MM cell lines and effects of galectin-3 inhibition <i>in vitro.</i> by Leonardo Mirandola (214035)

“…<p>(<b>a</b>) The lysates in each lane are as follows: 1 MM-1S; 2 MM-1RL; 3 NCI-H929; 4 RPMI-8226; 5 Dox-40; 6 LR-5; 7 ARP-1; 8 ARB-B; 9 U266. Indicated MM cell lines were seeded at 300,000 cells/mL and maintained at 37°C and 5% CO₂. …”

FGFR2b-ligands signaling controls cell proliferation in the mesenchyme of the limb bud. by Soula Danopoulos (346564)

“…<p>(<b>A–D</b>) Phosphohistone H3 and E-cadherin double IF staining in control E11.5 (<b>A,B</b>) and DTG [<i>R26^rtTA/rtTA; Tg/Tg</i>] (<b>C,D</b>) limb bud exposed to Dox-IP at E10.5 and analyzed at E11.5 demonstrate significant reduction in cell proliferation of both the AER and the adjacent mesenchyme. …”

Inhibition of AKR substrate reduction by β-glucogallin. by Muthenna Puppala (175119)

“…<p>The IC₅₀ was determined to be 58±3 µM (SEM) under saturating conditions of the shared substrate glyceraldehyde. β-glucogallin showed no activity against AKR1B10 and AKR1A1 at all concentrations tested under saturating conditions of glyceraldehyde as indicated. …”

XAV939 inhibits TNKS PARP-activity in MB cell lines. by Cristiano Renna (585758)

“…<p>WB analysis and densitometry of total and nuclear MB cells extracts after XAV939 treatment: MB cell lines (DAOY, ONS-76) were treated with 5 μM XAV939 or with an equal volume of DMSO. <b>A.…”

Optimal hydrated lime concentration in asphalt binder to improve photo degradation resistance by André Gustavo Banja (5110844)

“…HL was added to the binder in contents of 5, 10, 20, and 30 wt.%. The HL modified binders were aged by using the Rolling Thin Film Oven Test and weathering tests with xenon radiation. …”

Supplementary Material for: Nomograms of Fetal Right Ventricular Fractional Area Change by 2D Echocardiography by Guirado L. (6174176)

Trends of self-rated health in relation to overweight in the adult population in Brazilian Midwest capitals by Lúcia Stela Pessanha Lopes de Souza (4660603)

“…There was an average increase of 0.5 percentage point per year in the categories “fair” and “good” and an average decrease of 1.0 percentage point in the category “very good”. …”

Data_Sheet_1_Transcriptome Analysis of the Nematode Caenorhabditis elegans in Acidic Stress Environments.ZIP by Yanyi Cong (9359063)

Data_Sheet_2_Transcriptome Analysis of the Nematode Caenorhabditis elegans in Acidic Stress Environments.PDF by Yanyi Cong (9359063)

MβCD treatment is effective in sequestering cholesterol from the plasma membrane. by Bárbara Hissa (176168)

“…(D) Cardiomyocytes treated with 5, 10 or 15 mM of MβCD reveal a substantial decrease in Filipin labeling in a dose-dependent manner whereas cholesterol replenishment with 0.05 mM of WSC returns Filipin fluorescence to control values. …”

Following OGD mTOR phosphorylation is reversed by rapamycin treatment. by Lauren Fletcher (353321)

“…<p>Primary cortical neurons were subjected to 1 h OGD and then treated with rapamycin (20 nM) or vehicle (0.01% EtOH) for multiple time points (1.5 h–24 h). (A,B) Following OGD, rapamycin significantly decreased the phosphorylation of mTOR at both Ser-2448 and Ser-2481 compared to vehicle for all time points. …”

Loss of auditory function and the generation of sensory cell apoptosis following exposure to noise. by Minal Patel (385459)

“…<p>(<b>A</b>) Comparison of the ABR thresholds (dB, mean ± SD) measured at three time points: pre-noise exposure and 2 h and 1 d post-noise exposure. …”

MST1/2 in PDGFR-α+ cells negatively regulates TGF-β-induced myofibroblasts accumulation in renal fibrosis by Yina An (11511342)

Figure CSA-2 4.18 by CIMR project (7352015)

“…Both the mean error and standard deviations clearly decrease with the addition of the MW data. Errors are reduced at a similar rate globally for both January and July.…”

FigShare Figure 4. Targetable sites to introduce pathogenic variants with prime editors. by John Morris (8904362)

“…<b>(a)</b> Total number of ClinVar pathogenic variants, broken down by mutation type (transition, transversion, insertion or deletion) and the decrease in the percentage that can be introduced with prime editing under different conditions. …”

Loss of OPCs starts during the first postnatal week in the corpus callosum after genetic ablation of <i>C1ql1</i>-expressing OPCs. by Shayan Moghimyfiroozabad (19066182)

“…PDGFRa^pos (yellow arrowhead) and PDGFRa^neg (white arrowhead) GFP^pos cells are identified in the CC-center, CC-lateral, and the cortex. Scale bars = 50 μm. Quantification of GFP^pos (green) and PDGFRa^pos GFP^pos (magenta) cells shows a decrease in the density of OPCs in CC-lateral, but not in CC-center or in the cortex of <i>C1ql1</i>^<i>Cre</i><i>; Sox10</i>^<i>DTA</i> mice compared to controls. …”