Roles of HSC70 and Cofactor DjA1 in KCNQ4 Biogenesis. by Yanhong Gao (244711)

“…Knockdown of HSC70 or DJA1 resulted in a significant decrease in total KCNQ4 level. Each data point in the bar graphs represents the mean ±SD of three experiments (* p≤0.05, ** p≤0.01).…”

Dotted and solid lines represent, respectively, countries with and without substantial slum populations. by Julius Alexander McGee (4672354)

“…While, at higher levels of urbanization, the rate of increase in CIWB for countries without substantial slum populations begins to slow down, there is no turning point at which the CIWB begins to decrease. Moreover, as we also see from the estimates in Model 4, having a substantial slum population actually moderates the association between urbanization and CIWB, although the relationship is more approximately linear.…”

Pumpless, “Self-Driven” Microfluidic Channels with Controlled Blood Flow Using an Amphiphilic Silicone by Kokou S. Dogbevi (8636739)

“…Such a system would be especially useful toward developing a single use, optical imaged point-of-care (POC) device. While readily used to prepare microfluidics via soft lithography, silicones inhibit capillary flow of blood due to their extreme hydrophobicity. …”

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice by Asimina Hiona (246175)

“…D257A mice display impaired mitochondrial bioenergetics associated with compromised state-3 respiration, lower ATP content and a resulting decrease in mitochondrial membrane potential (Δψ_m). …”

HIV-1 Nef Inhibits Protease Activity and Its Absence Alters Protein Content of Mature Viral Particles by Luiza M. Mendonça (584366)

“…Collectively, our data support the hypothesis that the decreased infectivity typical of <i>nef</i>-deficient viruses is due to an abnormal function of the viral Protease, which is in turn associated with less mature particles being produced and the loss of Integrase content in these particles, and these results may characterize Nef as a regulator of viral Protease activity.…”

Table_1_Transforming Growth Factor (TGF) β and Endometrial Vascular Maturation.docx by Qinsheng Lu (778233)

“…Our previous data demonstrated an increase in TGFβ1 in the endometrium of RPL, while others have shown a decrease in women with HMB. However, TGFβ1 bioavailability is tightly controlled, and we therefore sought to perform an extensive immunohistochemical analysis of different components in the pathway in the endometrium of normal controls, women with HMB or RPL. …”

Table_1_Non-invasive Biomarkers of Liver Inflammation and Cell Death in Response to Alcohol Detoxification.DOCX by Manuela G. Neuman (11086812)

“…Fibrosis stage and steatosis were assessed by measuring liver stiffness (LS) and controlled attenuation parameter (CAP) in all patients using transient elastography (FibroScan, Echosens, Paris). Mean observation interval between the measurements was 5.7 ± 1.4 days (mean + –SD).…”

NHR-80 can function in the absence of <i>daf-16</i> but requires <i>daf-12</i>. by Jérôme Goudeau (228021)

“…When <i>daf-16(mu86);glp-1(e2141ts)</i> mutants are compared to <i>glp-1(e2141ts)</i> mutants, there is a 1.5-fold decrease (Wilcoxon rank-sum test <i>p</i> value <0.05). …”

Table 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Data Sheet 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Table 2_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Table 4_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Table 3_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Image 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.pdf by Ana Virseda-Berdices (9638081)

“…Background<p>HCV eradication with antiviral treatment reduces hepatic disease, but some patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to examine the association between peripheral blood mononuclear cells (PBMCs) gene expression before HCV therapy and a pronounced decrease in the liver stiffness measurement (LSM) value in HIV/HCV-coinfected patients after HCV treatment and achievement of sustained virological response (SVR).…”

Non-contributory pension programs and frailty of older adults: Evidence from Mexico by Emma Aguila (3461918)

Enhancing the number of human otic sensory cells by Notch inhibition. by Hanae Lahlou (5394905)

“…(D) The decrease of Notch pathway components after DBZ treatment was accompanied with a significant upregulation of two otic sensory markers (<i>ATOH1</i>, <i>MYO7A</i>) transcripts. …”

Contrasting effects of necrotrophic and biotrophic plant pathogens on the aphid Aphis fabae by Al-Naemi, F.

“…However, sequential plant infection (pathogens applied 5 days apart) led to a 70% decrease in fecundity and 50% reduction in intrinsic rate of increase. …”
Get full text
Get full text

Hypoxia and hyperoxia alter NO levels and can drive vasodilation and vasoconstriction. by William Davis Haselden (9175156)

“…<p>All simulations in this figure used a dynamic model. In these simulations we varied arterial oxygen concentration, and the baseline diameter of the vessel was 50μm. …”

<i>lin-4</i> and its targets <i>lin-14</i> and <i>lin-28</i> are expressed reciprocally during larval development. by Katherine Olsson-Carter (244338)

“…*p-value = 0.012. ***p-values<0.001 (2.5×10⁻⁵ for L3 and 6.3×10⁻⁷ for L4). …”

Frequency and voltage range of noise-dependent MPOs in neuropathic model. by Young-Ah Rho (162030)

“…Spike threshold was estimated as the voltage at the inflection point for <i>dV</i>/<i>dt</i>. Sample response shows progressive inactivation (decrease in <i>h</i>; <i>green</i>) and the corresponding rise in spike threshold (<i>red</i>) which eventually leads to the termination of repetitive spiking. …”