Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP^Sc Glycoform and Prion Infectivity by Elizaveta Katorcha (628696)

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

The effects of β₁-adrenoceptor stimulation on I_Kur and I_Kto,f. by Vladimir E. Bondarenko (411443)

“…Simulated currents are obtained by 4.5-s depolarizing pulses to between −80 and +50 mV (in 10-mV increment) from a holding potential of −90 mV. …”

Royal jelly arranges apoptotic and oxidative stress pathways and reduces damage to liver tissues of rats by down-regulation of Bcl-2, GSK3 and NF-κB and up-regulation of caspase an... by Abdullah Aslan (9997699)

“…</p> <p><b>Results</b></p> <p>RJ caused a significant decrease in MDA level, Bcl-2, GSK3 and NF-κB protein expression levels, whereas induced a significant increase in GSH level, CAT activities and Bax, BDNF, caspase-6, caspase-3, Nrf-2 protein expression levels.…”

Table_1_Management of Donor-Specific Antibodies in Haploidentical Transplant: Multicenter Experience From the Madrid Group of Hematopoietic Transplant.pdf by Rebeca Bailén (10430765)

“…</p>Results<p>We identified a total of 20 haplo-HSCT in 19 patients performed with DSAs in 5 centers. 10 (53%) patients presented anti-HLA class I DSAs (6 of them with > 5000 mean fluorescence intensity (MFI)), 4 (21%) presented anti-HLA class II (1 with > 5000 MFI) and 5 (26%) presented both anti-HLA class I and II (5 with > 5000 MFI). 90% of patients received at least two treatments as desensitization strategy and all experienced a decrease of MFI after desensitization (mean reduction 74%). …”

Polyol-responsiveness of anti-EBNA1 mAbs. by Sarah J. Duellman (374308)

“…After the anti-EBNA1 mAbs are bound to the EBNA1-coated well, either a control buffer (TE: 50 mM Tris-HCl, pH 7.9+0.1 mM EDTA) or a salt-polyol buffer (AS/PG: TE buffer+1 M ammonium sulfate+40% propylene glycol or NaCl/PG: TE buffer+1 M NaCl+40% propylene glycol) was added to the wells. …”

FRACTAL AGGREGATES EVOLUTION DURING FLOCCULATION by R. B. Moruzzi (6542864)

“…The Gf values of 20, 30, 40, 50 and 60 s-1 and Tf values of 2 to 180 minutes were studied, with a ΔTf of 1 minute for 2 ≤ Tf ≤ 10 minutes and a ΔTf of 5 minutes for 10 ≤ Tf ≤ 180 minutes. …”

MyD88 plays an important role in early neutrophil recruitment after infection with <i>B. pseudomallei</i>. by W. Joost Wiersinga (33895)

“…LIX levels were unaltered in MyD88 KO mice at this early time point (F). SSC, side scatter; FITC: fluorescein isothiocyanate; PE, phycoerythrin; MFI, mean fluorescence intensity; MPO, Myeloperoxidase; MIP-2: macrophage-inflammatory protein-2; LIX, lipopolysaccharide-induced CXC chemokine. …”

Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling-6 by Troels Schepeler (79446)

Obese <i>Ugcg</i>^{f/f//CamKCreERT2} mice are initially slightly hyperphagic and show hypometabolism and hypothermia. by Viola Nordström (388258)

“…(<i>n</i> = 9) (LM). Individual means. (C) Metabolic rate of <i>Ugcg</i>^{f/f//CamKCreERT2} mice was decreased 5 and 9 wk p.i., indicating lower energy expenditure (<i>n</i> = 7–10); <i>p</i> = 0.073 week 5; <i>p</i> = 0.77 week 11 (LM). …”

Quantitative Analysis of the Extracellular Response Kinase 1 and 2 (ERK1/2), Calcium-Calmodulin Kinase II (CAMKII), Fragile X Protein (FMRP), and the Nicotinic Acetylcholine Recept... by Robert K. Naviaux (256148)

“…<p>(A) ERK1 (MAPK3) and ERK2 (MAPK1) phosphorylation was decreased by over 90% by gestational poly(IC) exposure and normalized by suramin treatment (Sal-Sal = 100+/−5%; Sal-Sur = 6.2+/−0.8%; PIC-Sal = 9.9+/−2.6%; PIC-Sur = 84+/−2.3%; one-way ANOVA F(3,12) = 241; p<0.0001; n = 4–5 males per group; age = 16 weeks). …”

Dephosphorylation of ERK1/2 is involved in the WIN-induced down regulation of MMP-9 mRNA, but not in the effect of WIN on MMP-9 protein. by Svantje Tauber (121637)

“…WIN treatment resulted in a dephosphorylation of ERK associated with inhibition of secretion, intracellular accumulation and decrease of MMP-9 mRNA (lanes 1 and 2). …”

Parameter sensitivities. by Julio M. Belmonte (204008)

“…Parameters changes one-at-a-time with remaining parameter set to their reference values. …”

DataSheet1_Long-Term Variation in Wintertime Atmospheric Diffusion Conditions Over the Sichuan Basin.docx by Guoyin Wang (10939987)

“…Both V_E and ASI reveal a decrease tendency of atmospheric diffusion condition from the northwestern portion of the basin to the southeast. …”

Supplementary Material for: Headache in Pediatric Moyamoya Disease after Revascularization Surgery by Yang J. (3341234)

“…<b><i>Introduction:</i></b> Patients with moyamoya disease (MMD) often have headaches after successful revascularization surgery. We aimed to characterize headache in surgically treated MMD patients and elucidate its clinical meaning and pathophysiology. …”

Table_1_Multivariate piecewise linear regression model to predict radiosensitivity using the association with the genome-wide copy number variation.xlsx by Joanna Tobiasz (11816504)

“…The weighted mean relative errors (MRE) decreased with increasing the segments' number. …”

RAD21 is necessary for ERα binding within the <i>MYC</i> locus but not an exogenous ERE. A) RAD21 silencing abrogates ERα binding upstream of <i>MYC</i>. by Miranda V. McEwan (121381)

“…Firefly luciferase activity was normalized to <i>Renilla</i> luciferase activity, and expressed as relative luciferase units (RLU). The mean ± SEM (n  = 5 biological replicates) is shown. …”

Impact of fruit-tree shade intensity on the growth, yield, and quality of intercropped wheat by Xu Qiao (4600141)

“…The photosynthetic rate of wheat in the jujube-, apricot-, and walnut-based intercropping systems decreased by, respectively, 11.3%, 31.9%, and 36.2% compared to monoculture wheat, and the mean number of fertile florets per spike decreased by 26.4%, 37.4%, and 49.5%. …”

Intravenous Ibuprofen for Treatment of Post-Operative Pain: A Multicenter, Double Blind, Placebo-Controlled, Randomized Clinical Trial by Andrea Gago Martínez (2734993)

“…The primary outcome measure was median morphine consumption within the first 24 hours following surgery. The mean±SEM of morphine requirements was reduced from 29,8±5,25 mg to 14,22±3,23 mg (p = 0,015) and resulted in a decrease in pain at rest (p = 0,02) measured by Visual Analog Scale (VAS) from mean±SEM 3.34±0,35 to 0.86±0.24, and also in pain during movement (p = 0,02) from 4.32±0,36 to 1.90±0,30 in the ibuprofen treatment arm; while in the placebo group VAS score at rest ranged from 4.68±0,40 to 2.12±0,42 and during movement from 5.66±0,42 to 3.38±0,44. …”

Inhibition of β-catenin by resveratrol and inh21 enhances endothelial marker expression. by Paola Campagnolo (737176)

“…<p>Levels of activated β-catenin (ABC) were reduced by resveratrol treatment (A). Transfection of vessel resident progenitor cells with miR21 inhibitor (inh21) decrease ABC expression, as compared to the negative control (inhNC, B). …”