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Overconfident results with the bivariate random effects model for meta-analysis of diagnostic accuracy studies
Published 2022“…In 2001, Rutter and Gatsonis proposed the hierarchical summary receiver operating characteristic (HSROC) model,1 and in 2004 Macaskill described an empirical Bayes approach.2 Soon after, in 2005, Reitsma et al. proposed the bivariate random effects model,3 which has been widely adopted and is the most commonly used method for diagnostic meta-analysis.4 However, as pointed out by Diaz,5 the statistical performance of the bivariate model has not been scrutinized. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
Published 2016“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
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Experimental Investigation on the Flexural Capacity of Reinforced Concrete Beams with Treated Wastewater and Recycled Concrete Aggregates
Published 2023“…In addition, the utilization of FA at a 20% replacement ratio enhanced the flexural strength by 5% to 7%.…”
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DEVELOPMENT AND EVALUATION OF VIRTUAL REALITY EXERGAMES FOR UPPER LIMB AMPUTEE REHABILITATION
Published 2024“…User evaluation revealed positive user satisfaction(ratings: 3.8 to 4.5 on a 5-point Likert Scale). Quantitative analysis of the box and block test scores across 10 healthy participants for the motor skills assessment revealed a strong correlation (r = 0.99, P < 0.001) between training sessions and the evaluation scores. …”
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …”
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …”
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Thermal properties of phase-change materials based on high-density polyethylene filled with micro-encapsulated paraffin wax for thermal energy storage
Published 2015“…Microcapsules consisting of paraffin wax cores with a melting point of approximately 42 °C and a melamine-formaldehyde resin shell were synthesized using in situ polymerization. …”
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Thermal and mechanical characterization of injection moulded high density polyethylene/paraffin wax blends as phase change materials
Published 2014“…Elongation at break decreased as paraffin wax content increased, and Young's modulus decreased with wax content but in the case of blends with a 30vol. % of wax and more, brittle rupture occurred and no yield point was observed.…”
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