datasheet1_Mutations of N1 Riboswitch Affect its Dynamics and Recognition by Neomycin Through Conformational Selection.pdf by Piotr Chyży (10159391)

“…Indeed, simulations of the unbound riboswitch show that G17 frequently stacks with base 7, while base 8 is stabilized towards the binding site in a way that it may interfere with the conformational selection mechanism and decrease riboswitch regulatory activity. In the riboswitch complexes, this single-point A to G mutation disrupts a strong hydrogen bond between nucleotides 5 and 17 and, instead, a new hydrogen bond between residue 17 and neomycin is created. …”

Supplementary file 1_Analysis of gender- and age-stratified asthma burden: forecasting prevalence trends in 2030.docx by Zhenzhen Pan (2637463)

“…Both incidence and prevalence in China are projected to decrease in the future.</p>Conclusion<p>This study finds 15–19 years is a key turning point for gender differences in asthma burden, pinpointing smoking, high BMI, and NO₂ as risk factors. …”

datasheet1_Mutations of N1 Riboswitch Affect its Dynamics and Recognition by Neomycin Through Conformational Selection.pdf by Piotr Chyży (10159391)

“…Indeed, simulations of the unbound riboswitch show that G17 frequently stacks with base 7, while base 8 is stabilized towards the binding site in a way that it may interfere with the conformational selection mechanism and decrease riboswitch regulatory activity. In the riboswitch complexes, this single-point A to G mutation disrupts a strong hydrogen bond between nucleotides 5 and 17 and, instead, a new hydrogen bond between residue 17 and neomycin is created. …”

Table_1_Influences of Canopy Nitrogen and Water Addition on AM Fungal Biodiversity and Community Composition in a Mixed Deciduous Forest of China.docx by Aihua Zhao (136578)

“…We found that (1) in the 1st year, N addition, water addition and their interactions all exhibited significant influences on AM fungal community composition; (2) in the 2nd year, only water addition significantly reduced AM fungal alpha-diversity (richness and Shannon index); (3) in the next 2 years, both N addition and water addition showed no significant effect on AM fungal community composition or alpha-diversity, with an exception that water addition significantly changed AM fungal community composition in the 4th year; (4) the increment of N or water tended to decrease the abundance and richness of the dominant genus Glomus and favored other AM fungi. (5) soil pH was marginally positively related with AM fungal community composition dissimilarity, soil NH₄⁺-N and N/P showed significant/marginal positive correlation with AM fungal alpha-diversity. …”

Token merging module. by Wen-Qing Huang (5258126)

“…Experimental results demonstrate that compared to the baseline model, the proposed enhanced model achieves a reduction of 2.5G Flops computational complexity and a 16% speed improvement on a private pavement disease dataset, with only a 1.2 percentage point decrease in AUC accuracy. …”

Prenylated Polyphenols from <i>Clusiaceae</i> and <i>Calophyllaceae</i> with Immunomodulatory Activity on Endothelial Cells by Caroline Rouger (1523164)

“…Here, 13 polyphenols belonging to 5 different chemical types of secondary metabolites (i.e., mammea coumarins, a biflavonoid, a pyranochromanone acid, a polyprenylated polycyclic acylphloroglucinol (PPAP) and two xanthones) were tested on resting and cytokine-activated EC cultures. …”

Cold shock of <i>Yersinia pseudotuberculosis</i> IP32953. by Xiaojie Jiang (4759644)

“…(B) Relative mRNA expression levels of DEAD-box RNA helicase genes <i>rhlB</i>, <i>csdA</i>, <i>dbpA</i>, <i>rhlE</i> and <i>srmB</i> in three independent cold-shocked (rapid decrease from 28°C to 3°C) cultures compared to pre-cold-shocked cultures at each time point (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0219422#pone.0219422.s003" target="_blank">S3 Table</a>). …”

Table_4_Proteomic analysis reveals semaglutide impacts lipogenic protein expression in epididymal adipose tissue of obese mice.xlsx by Ruiyi Zhu (13963501)

“…Bioinformatics analysis showed a reduction of CD36, FABP5, ACSL, ACOX3, PLIN2, ANGPTL4, LPL, MGLL, AQP7, and PDK4 involved in the lipid metabolism in the Sema group accompanied by a decrease in visceral fat accumulation, blood lipids, and improvement in glucose intolerance.…”

An Atypical Mitochondrial Carrier That Mediates Drug Action in <i>Trypanosoma brucei</i> by Juan P. de Macêdo (735541)

“…Metabolomic analyses of parasites over-expressing TbMCP14 showed increased levels of the proline metabolite, pyrroline-5-carboxylate, suggesting a possible involvement of TbMCP14 in energy production. …”

Gadolinium Retention 10 years after Gd-CM - Gd-Concentrations in Spot - and CEMET Urine by Thomas Clemens Carmine (19756929)

“…</p><p dir="ltr">By six months post-Gd-CM, gadolinium concentrations in spontaneous urine are typically below detectable levels (see also https://doi.org/10.6084/m9.figshare.27131922.v1). By contrast, gadolinium remains quantifiable in CEMET urine, with the rate of decline slowing after this point. …”

Table_2_Proteomic analysis reveals semaglutide impacts lipogenic protein expression in epididymal adipose tissue of obese mice.xlsx by Ruiyi Zhu (13963501)

“…Bioinformatics analysis showed a reduction of CD36, FABP5, ACSL, ACOX3, PLIN2, ANGPTL4, LPL, MGLL, AQP7, and PDK4 involved in the lipid metabolism in the Sema group accompanied by a decrease in visceral fat accumulation, blood lipids, and improvement in glucose intolerance.…”

Action potential amplitude and shape vary with firing rate for the majority of neurons. A by Peter Stratton (158746)

“…These points were then used to calculate spike rise time, fall time and half width (respectively blue, green and red lines on the graphs A2 and A4) for each spike bin. …”

Comparative results of the ablation experiments. by Wen-Qing Huang (5258126)

“…Experimental results demonstrate that compared to the baseline model, the proposed enhanced model achieves a reduction of 2.5G Flops computational complexity and a 16% speed improvement on a private pavement disease dataset, with only a 1.2 percentage point decrease in AUC accuracy. …”

DataSheet_1_Immune responses during COVID-19 breakthrough cases in vaccinated children and adolescents.pdf by Daniela Rivera-Pérez (10700565)

The effect of stress on sound processing increases with repeated exposure. by Ghattas Bisharat (20706928)

“…We found a negative slope in most PPY and PV cells, indicating a decrease in activity as the stress becomes chronic (<i>t</i> test for PPY cells <i>p</i> = 9.8 × 10⁻¹⁴, PV cells <i>p</i> = 0.006) and a positive slope for SST cells indicating an increase in activity with successive applications of the stressor (<i>t</i> test for SST cells <i>p</i> = 9.5 × 10⁻⁰⁶). …”

Variation of average codeword length (ACL) by number of edges. by Dario Elias (8882177)

“…A positive variation indicates a decrease in the ACL. …”

Table_1_Do changes in working hours increase stress in Japanese white-collar workers?.DOCX by Masaki Ozawa (2354584)

“…</p>Results<p>We observed a greater increase in stress among female who worked 41–50 h per week at T1 and more than 50 hours per week at T2, and those who worked more than 50 h per week at T1 and 35–40/41–50 h per week at T2, compared to those who worked 41–50 h per week both at T1 and T2, with odds ratios (ORs) and 95% confidence intervals (95% CI) of OR = 2.09, 95% CI (1.18, 3,70); OR =1.86, 95% CI (1.14, 3.03), respectively. …”

The kava root extract and kavalactones down-regulate expression of AR and AR target genes (<i>PSA</i> and <i>TMPRSS2</i>) via accelerating the degradation of AR protein. by Xuesen Li (48046)

“…The protein expression of AR and PSA in LNCaP and C4-2B cells after indicated treatments at a concentration of their IC_{50 s} for 16 hours was analyzed by Western blot. α-Tubulin was detected as a loading control. …”

Circular Dichroism analysis, PPIase activity and nickel regulation of <i>H</i>. <i>pylori</i> WT and mutant SlyD proteins. by Milica Denic (9987685)

Gene expression comparison between <i>C. albicans</i> alone and drug-treated groups in <i>Galleria mellonella</i>. by Nadja Rodrigues de Melo (485602)

“…On the other hand this treatment also caused a significant decrease of gene expression of IMPI, C5 (*p<0.001), C6 and C7 (**p<0.05). …”