Histone deacetylase (HDAC) inhibitor assessment. by Ilona Tkachyova (343715)

“…ITF 2357, an HDAC inhibitor which is structurally and functionally similar to SAHA, produced a dose-response curve with IC₅₀ of 0.2 μM. …”

WIDS 2020 Poster(Wafaa Alabsi).pdf by Wafaa Alabsi (8704977)

“…</p> <p><b>Results</b></p> <p>The glycosylation of numerous peptides synthesized in our group including PNA5 has been shown to increase enzymatic stability and penetration of the BBB; decrease the clearance rate; thus, increase the half-life (t_1/2), the area under the curve (AUC) and the maximum concentration C_max.…”

Table 1_Elucidating the effects of nine-steaming-nine-drying on the morphology, metabolomic profile, and active ingredients of Polygonatum sibiricum Redouté.xls by Rui Wang (52434)

“…These alterations resulted in darker coloration, as evidenced by a significant decrease in L* values, elimination of tongue-numbing effects, enhanced sweetness, and improved quality of P. sibiricum Red. …”

Pre- and postsynaptic components of altered Panx1^−/− LTP. by Nora Prochnow (4627)

“…Adenosine treatment normalized the input sensitivity of the Panx1^−/− towards values of the untreated controls (Panx1^+/+). d, fEPSP sample traces of the Panx1^−/−, revealing a decrease in oscillatory activity (arrow) and amplitudes. e, NMDA dependence of ^−/− and ^+/+ derived LTP after application of 50 µM D-AP5. …”

Forms of lime application and use of phosphogypsum in low acid soil in southern Brazil: soybean-wheat yield and soil chemical properties by Marcos Renan Besen (5554829)

“…Incorporated liming caused a decrease in soil Al3+ levels until 0.60 m depth, whereas SL decreased Al3+ levels until 0.30 m depth. …”

DataSheet_1_Host-Induced Silencing of FMRFamide-Like Peptide Genes, flp-1 and flp-12, in Rice Impairs Reproductive Fitness of the Root-Knot Nematode Meloidogyne graminicola.docx by Alkesh Hada (9141278)

“…This also led to significant decrease in total number of endoparasites by 31–50% for Mg-flp-1 and 34–51% for Mg-flp-12 transgenics. …”

Regulation of nestin expression by thrombin and cell density in cultures of bone mesenchymal stem cells and radial glial cells-0 by Franz Wautier (86113)

High dose wIFN-α significantly induced intrahepatic expression of T cell, NK cell and IFN-γ response genes. by Simon P. Fletcher (793613)

“…For genes where wIFN-treated < placebo, the fold change ratio was calculated by -1 x (placebo/ treated), i.e. -1.50 equals a 50% decrease in treated vs. placebo.…”

Ca²⁺ sensitivity of the contractile apparatus and maximum Ca²⁺-activated force. by Thomas J. Harvey (800460)

“…Male C (n = 10) and NR (n = 8) showed no significant difference in the relative amount of TnC, however there was a reduction in the amount of cTnI from NR samples, showing a significant decrease compared with controls (unpaired t-test, *P<0.05). …”

Overexpression of miR-105 inhibits tumour cell growth but does not induce apoptosis. by D. Rice Honeywell (442714)

“…<p>(A–B) Tumour cells were transfected with either 50 nM miR-105 (closed squares) or control (open circles) mimics and subsequently seeded into 96-well plates in replicates of 8. …”

Supplementary Material for: Intravitreal Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Clinical Practice of Single Center: Three-Year Outcomes by Choovuthayakorn J. (10496261)

“…However, when initial VA was 20/40 and better, a non-statistically significant change in mean VA by +2.0, −3.5, and −3.6 letters were noted at the same time point (<i>p</i> value between 0.078 and 0.273). …”

Impact of precipitation and temperature changes on hydrological responses of small-scale catchments in the Ethiopian Highlands by Tatenda Lemann (3187935)

“…Results indicate that runoff reacts disproportionately strongly to precipitation and temperature changes: a 24% increase in precipitation led to a 50% increase in average annual runoff, and an average annual rainfall–runoff ratio that was 20% higher. …”

Synaptic weights are optimal with respect to output noise. by John Porrill (35799)

“…<p>Here the plant suffers a 50% decrease in gain and learning takes place in 4 PFs carrying levels <i>α</i>_i = 1, 1, 2, and 2 of the same unit power signal <i>s</i> and levels <i>σ</i>_i = 1/2, 1, 1/2, and 1 of independent noise (see legend below for [A]). …”

NF-κB regulation of mesodermal and neural markers: by Chi Zhang (9857)

“…G: Treatment of early embryos with AKBA (50 µM from the 4-cell stage on) lead to a decrease in <i>Xbra</i> staining (control and AKBA-treated embryos marked). …”

Effects of resistance exercise versus combined training on post-exercise hypotension in women with metabolic syndrome by Ramires Alsamir Tibana (8977688)

“…Therefore, RE and COMB elicited post-exercise hypotension in women with MS; COMB provided a greater decrease which may be of value in the prevention and treatment of cardiovascular disorders.…”

Optimization of the Malachite-Green ATPase assay for EHD4^ΔN. by Saif Mohd (19251157)

“…<b>B</b> MLG-based ATPase assays for 4 μM EHD4^ΔN, 500 μg/ml DOPS and 50 μM ATP were done at 37°C and 30°C. A further decrease to 25°C did not affect the enzymatic activity compared to 30°C (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0302704#pone.0302704.s002" target="_blank">S2I Fig</a>). …”

mIMCD-3 cells as an <i>in vitro</i> model to examine target genes of endogenous tRA/RARs. by Yuen Fei Wong (133656)

“…</b> Treating cells with 1 µM AGN193109 for 24 h resulted in a decrease of RARE-luciferase activity to about 50% of that of the vehicle control group; the reduction was at least partially abolished with simultaneous addition of exogenous tRA at 0.01–1 µM, in a dose-dependent manner. ** and ***: p<0.01 and p<0.001, respectively. …”

Supplementary Material for: Differentiating ischemic optic neuropathy from glaucoma using diagnostic tests by Smeets F. (17818949)

Average changes in parameter trajectories. by Philippa J. Karoly (761618)

Sufficiently high Arp2/3 density is required to maintain the continuity of branched network architecture. by June Hyung Kim (22386484)