Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes by Robert Smith (2450401)

“…In addition, simvastatin caused a decrease in maturation and activity of legumain. Dysregulation of glucose metabolism and decreased legumain activity by simvastatin points out new knowledge about the effects of statins on skeletal muscle, and may contribute to the understanding of the myotoxicity observed by statins.…”

Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection by Zizhang Sheng (280791)

“…We also analyzed the presence of AID hotspots and coldspots at different points in lineage development and observed an average decrease in mutability of less than 10 percent over time. …”

Supplementary file 1_Estimating a minimum clinically important difference for the Developmental Behaviour Checklist – parent report.docx by Daniel L. Sutherland (22061309)

“…</p>Results<p>21 studies were included in the meta-analyses and indicated an average DBC total raw score decrease of 3.01 or 4.73 (depending on analytic methods) in randomised controlled trials, and an average decrease of 9.16 points in pre-post designs. …”

DataSheet_1_The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers.pdf by Eline van Diest (14330511)

“…We successfully enhanced the fraction of γδECTO-αCD3-dimers by shortening the linker length between the heavy and light chain in the anti-CD3 scFv, though this also decreased protein yield by 50%. …”

Septin 7 localization is perturbed by TTFields. by Nidhi Gera (528784)

“…The ratio of the average intensity of Septin 7 staining at midline that of the total staining within the cell in Sham (n = 10) and presence of TTFields at 150kHz (n = 9) or 500kHz (n = 8) showed a significant decrease in Septin accumulation at the midlines in cells treated with 150 kHz TTFields (<b>C</b>). …”

DataSheet1_Modeling the hydrodynamic wake of an offshore solar array in OpenFOAM.pdf by Martin van der Eijk (19498426)

Data_Sheet_1_Maternal Exercise Improves High-Fat Diet-Induced Metabolic Abnormalities and Gut Microbiota Profiles in Mouse Dams and Offspring.DOCX by Liyuan Zhou (5712599)

The probability of tumor nodule eradication increases with the increase of CTL number. by Claire Christophe (714134)

“…Other lines: same evolution when the mean killing time is decreased by 10%, 50% and 90%. (<i>E</i>) Mean time needed to eradicate the tumor nodule for the CTL population ((<i>T</i>_<i>S</i>)). …”

Tension between hysteresis and biphasic dose-response. by Jeffrey V. Wong (168573)

“…Hysteresis is measured by calculating the path difference 24 hours after an increase in serum from 0.01% or after a decrease from 10%. Biphasic response is measured 36 hours after an increase in MYC synthesis (parameter ke_MC; <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002491#pcbi.1002491.s007" target="_blank">Text S1</a>). …”

Electrically Induced Liquid Metal Droplet Bouncing by Shubhi Bansal (4491013)

Nut1/Hos1 and Sas2/Rpd3 control the H3 acetylation of two different sets of osmotic stress-induced genes by María E. Pérez-Martínez (7376762)

Rice yields and the effect of weed management in an organic production system with winter flooding by Toru Uno (9869996)

The effects of laser acupuncture on the modulation of cartilage extracellular matrix macromolecules in rats with adjuvant-induced arthritis - Fig 5 by Tien-Chien Pan (6475403)

“…Different italic letters indicate significant differences between groups using Scheffe’s post hoc test (P < 0.05). A scale bar indicates 50 μm.</p>…”

Dose response analysis of active compounds identified in the primary HTS. by Kishore Polireddy (153876)

“…<p>(a) ABCB6 expressing cells showed dose dependent decrease in median channel fluorescence (representing PPIX fluorescence) in response to benzethonium chloride, verteporfin, and to a lesser extent piperlongumine. …”

Synaptic facilitation between tail SNs and MNs following sensitizing tail shocks declined during aging. by Andrew T. Kempsell (738294)

“…C) Monosynaptic facilitation between tail SNs and MNs following sensitizing tail shocks decreased during aging. A single AP evoked in tail SNs by 50 ms injected current resulted in a monosynaptic EPSP in tail MNs in mature (n = 14) and aged II (n = 13) preparations. …”

Secondary screening of primary hits reveals four true <i>p27^Kip1</i> inhibitors. by Brandon J. Walters (301187)

“…Dose-dependent luciferase inhibition (black) and alamar blue inhibition (blue) of each compound (n = 3, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091173#pone-0091173-t001" target="_blank">Table 1</a> lists the calculated IC₅₀’s). …”

The public health system and the place of autism by Vanini Mandaj (16029441)

“…Final Considerations: although the Psychosocial Care Network for Children is the reference in the region, it is known that this facility alone cannot meet all needs of individuals with autism spectrum disorder. A service network coordinated according to patient’s individual needs and the region's reality would ensure their expected rights, decrease public spending, and enable these users to occupy not only one but many places in society.…”

Ndk contributes to phagosome maturation arrest. by Jim Sun (367834)

“…In the bottom panel dotted circles indicate the position of Ndk-beads, while the red fluorescent signal (PKH) shows the location of BSA-beads and a significant decrease of dextran colocalization with distant PKH-BSA-beads. …”

Intracellular chloride measurements by Wallace B Thoreson (5462)

“…An example of the reduction in MEQ fluorescence, indicating an increase in intracellular [Cl], produced by application of 12.1 mM Kto a cone. C. A greater decrease in MEQ fluorescence was produced by application of 69.9 mM K. …”

The effect of loss of combinations of PAPs on the phenotype of <i>Salmonella</i>. by Helen E. McNeil (8190873)

“…Data presented is the time taken for the fluorescence to decrease by 25% +/- SE. (Data for 10% and 50% drop can be seen in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008101#ppat.1008101.s011" target="_blank">S1 Table</a>) <b>B</b>. …”