The p.Y47X, p.Q106X and p.I126S glaucoma-associated <i>FOXC1</i> mutations decrease protein stability. by Cristina Medina-Trillo (705087)

Ca²⁺ supplementation <i>in vitro</i> modulates cytokine production by primary human <i>i</i>NKT cells, Vδ2⁺ T cells, and MAIT cells. by Yusuf Cem Eskiocak (10789281)

Mutations altering LTD dynamics impair their lipid transport properties (a) Design of the STARD11-5P mutant at the omega loop (pink). by Sriraksha Srinivasan (7535654)

“…<b>(f)</b> Mass spectrometry profile of major sphingomyelins in HeLa cells; Hela cells <i>STARD11</i>-KO, and Hela cells <i>STARD11</i>-KO overexpressing STARD11-GFP WT (wt) or the STARD11-5P-GFP (5P) mutant. (<i>n</i> = 3; data are means ± SD; *<i>p</i> < 0.05, **<i>p</i> < 0.01; ***<i>p</i> < 0.001 [ordinary one-way ANOVA]). …”

Results from experiment 3, 4 and 5. by Olivia Carter (194606)

The knockdown of ApoB increased lipid accumulation and promoted HCV production. by Bei Wang (116772)

Loss of <i>FGR41</i> attenuates virulence in a host immune system dependent manner. by Andrew S. Wagner (11331477)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

Testing for soil-transmitted helminth transmission elimination: Analysing the impact of the sensitivity of different diagnostic tools by Marleen Werkman (543388)

“…Data from a Kenyan deworming study were used to parameterize the diagnostic model which was based on egg detection probabilities. …”

Flow chart for study selection. by Bruna Rubbo (287422)

“…All nine studies in six Asian countries showed reductions in pesticide suicide rates following HHP bans (range 28.0% to 91.9%), of which six applied time series analyses to account for trends prior to the intervention (reductions in pesticide suicide rates ranged 28.0% to 60.5%). Only five studies assessed overall suicides; of those, four reported decreases in overall suicide rates following the intervention, of which three used time series analysis (range 7.0% to 45.1%). …”

Engineering Two-Dimensional Mass-Transport Channels of the MoS₂ Nanocatalyst toward Improved Hydrogen Evolution Performance by Ge Wang (56838)

“…Because of the engineering of nanostructured channels, a reduction in overpotential by approximately 100 and 360 mV at −10 and −100 mA cm^–2, respectively, a decrease in the Tafel slope from 66.7 to 39.4 mV dec^–1, and a more stable operation can be achieved. …”

Flipping the Switch: Reverse-Demand Voltage-Sensitive Fluorophores by Jack T. McCann (13047830)

“…Our group has been developing voltage-sensitive fluorophores (VF dyes) that respond to changes in biological membrane potential (<i>V</i>_m). We hypothesize that the mechanism of voltage sensitivity arises from acceptor PeT (a-PeT) from an electron-rich aniline-containing molecular wire into the excited-state fluorophore, resulting in decreased fluorescence at negative <i>V</i>_m. …”

Mean area of CNV of laser spots delivered with different distances away from the optic disc. by Yanji Zhu (556453)

“…The mean CNV area tended to decrease as spots became farther away from the optic disc. …”

<i>Donson</i> deletion in the <i>Emx1</i> lineage reduces the size of the early dorsomedial pallium. by Sathish Venkataramanappa (10331993)

Table 5_Effects of mind-body exercise in chronic cardiopulmonary dyspnoea patients—a network meta-analysis of randomized controlled trials.docx by Yilin Li (507257)

Paired t test for the (A) Slow-4 and (B) Slow-5 frequency band, <i>p</i> < 0.05, AlphaSim corrected. by Lei Gao (6566)

RON5 is critical for host invasion but not egress. by Josh R. Beck (242399)

“…A minor decrease in penetration is also seen for untreated RON5_MYCcKD parasites, likely due to the lower levels of RON5 expressed in this strain relative to the parental line. …”

<i>Nkx2-1</i>-Cre-mediated deletion of <i>Donson</i> induces apoptosis in the mGE. by Sathish Venkataramanappa (10331993)

Neuroimaging findings. by Irene Flønes (849434)

“…C (upper lane): FDG-PET scan of the brain of patient 1 taken ~5 years later shows multiple foci of decreased glucose metabolism that correlate to the localization of the transient cortical signal changes on MRI. …”

Table_5_Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants.XLSX by Dominik Modrzejewski (5639621)

“…In addition, we ran a binary logistic regression analysis to verify five factors that may affect the occurrence of off-target effects: (1) Number of mismatches (2) Position of mismatches (3) GC-content of the targeting sequence (4) Altered nuclease variants (5) Delivery methods. …”

Image_5_Effects of dietary supplement with a Chinese herbal mixture on growth performance, antioxidant capacity, and gut microbiota in weaned pigs.PDF by Qinglei Xu (8497341)

“…A total of 400 weaned pigs [Duroc × (Landrace × Yorkshire)] were randomly allocated into one of four treatments: the CON group, fed with basic diet; the HM1 group, fed with basal diet supplemented with 0.5 g herbal mixture/kg diet; the HM2 group, fed with basal diet supplemented with 1.0 g herbal mixture/kg diet; or the HM3 group, fed with basal diet supplemented with 1.5 g herbal mixture/kg diet. …”