Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

HVR1-swap compensatory E1/E2 substitutions typically decrease virus entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

ABCC3 overexpression decreases the retention of anti-cancer agents. by Sai A. Balaji (1452556)

Tumor volume decreases with increasing <i>Salmonella</i> dosage. by Robert A. Kazmierczak (3140379)

Effect of decreased endogenous betaglycan expression on metanephric development and glomerulogenesis. by Kenneth A. Walker (280683)

Decreasing mean transistor size since 2000. by David Burg (8209752)

(R)-albuterol decreases cytokine protein levels in activated T cells by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”

(R)-albuterol decreases cytokine levels in activated murine splenocytes by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol (R), (S)-albuterol (S) or racemic albuterol (R + S) at a dose (10M) were added to murine splenocytes pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP), (Fig 3 A, B). …”

Expression of cerebral serotonin related to anxiety-like behaviors in C57BL/6 offspring induced by repeated subcutaneous prenatal exposure to low-dose lipopolysaccharide by Pei-Tan Hsueh (752475)

“…We concluded that maternal immune activation induced by exposure to a low dose of LPS decreased cerebral 5-HT levels in parallel to the down-regulation of the tph2 and slc6a4 genes and in conjunction with anxiety-like behaviors in offspring.…”

RL2 decreases viability and induces apoptosis in cultured cells. by Olga A. Koval (548122)

Dexamethasone decreases PGC-1α protein expression and transcription. by Jill A. Rahnert (2872766)

“…<p>(A) Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased PGC-1α protein expression (p = 0.01). n = 3/treatment from 3 experiments. …”

Dexamethasone decreases CRTC1 and CRTC2 nuclear localization. by Jill A. Rahnert (2872766)

“…<p>Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased (A) total CRTC1 (p = 0.004 and CRTC2 protein (p = 0.0007). n = 9/treatment from 3 experiments. …”

Pro- and anti-inflammatory cytokines are significantly decreased at acute time points following IR. by Jordan A. Gunning (18143970)

ST2-104 decreases the Aβ_25-35-mediated increase in intracellular Ca²⁺. by Yingshi Ji (9013004)

HSP90 inhibition by RGRN-305 decreased the gene expression of proinflammatory cytokines induced by SARS-CoV-2 S protein. by Hakim Ben Abdallah (14578241)

Rapamycin treatment significantly decreases induction of lytic KSHV proteins. by Lisa A. Nichols (357612)

19606 decreases the luminal pH of the ACV during infection. by Jesus S. Distel (11250759)

Mutation of Ser-473 in GC-A to alanine but not glutamate decreases ANP-stimulated guanylyl cyclase activity. by Andrea R. Yoder (165684)

Daily patterns of FF in a typical harmonic syllable across seven days of baseline and three days post 5-HT lesion (after the bird began singing again). by William E. Wood (491639)