Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

Image 5_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Methods<p>Mice were inoculated with 10⁷ CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. On day ten, mice were inoculated with 10⁵ PFU WT HSV-2 333 and survival, pathology, and viral titers were assessed. …”

Bacterial intracellular survival increases <i>in vivo</i> persistence in a mouse model of urinary tract infection and decreases antibiotic efficacy. by Cristina Penaranda (433703)

S5 Fig - by Cynthia Alsayyah (18452506)

“…This indicates that inhibiting the entry of citrate into mitochondria induces the same effects as inhibiting the synthesis of peroxisomal citrate (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002602#pbio.3002602.g005" target="_blank">Fig 5E</a>). …”

ALK^wt–ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain. by Vanessa Khemici (814639)

“…<i>fapR</i> mRNA levels were quantified by RT-qPCR using 16S rRNA as reference gene on total RNAs extracted from <i>wt</i> strain (PR01), <i>ΔcshA</i> strain (PR01-ΔcshA), and suppressor strains <i>ΔcshA/accC</i>^<i>M385V</i> (C51), <i>ΔcshA/accC</i>^<i>T183I</i> (sup30), <i>ΔcshA/accD</i>^<i>F253V</i> (sup17), <i>ΔcshA/accD</i>^<i>A164V</i> (sup16), <i>ΔcshA/birA</i>^{<i>D320F-FsX28</i>} (C58), <i>ΔcshA/birA</i>^{<i>R280stop</i>} (sup1) and <i>ΔcshA/bioY</i>^{<i>P123R-FsX1</i>} (C66), all at exponential growth phase in MH medium at 25°C. n = 5 for <i>ΔcshA</i>, <i>4 for wt</i> and 3 for all others. …”

The viability of human SH-SY5Y cells. by Tonglin Lu (6433043)

Immunostaining of lungs from a control mouse and a mouse infected with SARS-CoV-2. by Germán Ricardo Magaña-Ávila (18446799)

RMSD graphs for the backbone of WT PARG1, I845V and T622M mutants. by Zen Kouchi (14898435)

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

<i>Kpna1</i> KO mice show decreased anxiety-like behavior in the elevated plus maze. by Koki Sakurai (11690201)

Full-length PRR expression increases and sPRR secretion decreases in the absence of PACE4 in mouse. by Amro H. Mohammad (15081540)

<i>Il-17c</i> deletion decreases the expression of inflammatory cytokines. by Giovanna Vella (6413774)

Effects of vidarabine, V2E, V3E and V5E on AC activity in the heart of WT and AC5KO mice. by Kenji Suita (750993)

“…<p>(A) Vidarabine (Vida), V2E, V3E and V5E similarly and significantly decreased ISO (50 µmol/L)-stimulated AC activity in the WT heart in a dose-dependent manner. …”

Fig 5 - by Melissa A. Hill (13170105)

Excel spreadsheet containing, in separate sheets, the underlying numerical data and statistical analysis for Figure panels 1A-1D, 2D-2H, 3B, 4B, 4C, 4E, 5D, 5F, 5G, 5I-5M, 6A-6D, 6... by Yuru Wang (846969)