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points decrease » point increase (Expand Search)
point decrease » point increase (Expand Search)
ppm decrease » _ decrease (Expand Search), nn decrease (Expand Search), pa decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
3 points » _ points (Expand Search), 5 points (Expand Search), _ point (Expand Search)
e point » _ point (Expand Search), 5 point (Expand Search), a point (Expand Search)
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation.
Published 2022“…Either Prb1 or Snf7 in <i>snf7Δ</i> cells facilitated GFP-Atg8 degradation and prApe1 maturation (bottom), but only Snf7 (not Prb1) facilitated phagophore closure in <i>snf7Δ</i> cells. The red arrows point to these key results. <b>F.</b> The blots shown in panel E were quantified as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010431#pgen.1010431.g006" target="_blank">Fig 6A and 6B</a>. …”
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NatB-inactivation decreased Drk levels through its N-terminal sequences, which was regulated by the N-end rule E3 ubiquitin ligase POE/UBR4.
Published 2020“…Data were collected from eye discs containing MARCM clones similar to those shown in (A-C). (E-J) Wing discs containing FRT control or <i>psid</i> MARCM clones marked by GFP expression (pointed by arrowheads). …”
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