بدائل البحث:
fold decrease » fold increase (توسيع البحث), fold increased (توسيع البحث)
ppm decrease » _ decrease (توسيع البحث), nn decrease (توسيع البحث), pa decreased (توسيع البحث)
ht decrease » _ decrease (توسيع البحث), nn decrease (توسيع البحث), we decrease (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
2 fold » 5 fold (توسيع البحث), _ fold (توسيع البحث)
5 ht » 5 h (توسيع البحث)
fold decrease » fold increase (توسيع البحث), fold increased (توسيع البحث)
ppm decrease » _ decrease (توسيع البحث), nn decrease (توسيع البحث), pa decreased (توسيع البحث)
ht decrease » _ decrease (توسيع البحث), nn decrease (توسيع البحث), we decrease (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
2 fold » 5 fold (توسيع البحث), _ fold (توسيع البحث)
5 ht » 5 h (توسيع البحث)
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Additional Analysis of visually induced calcium transients in Fig 6.
منشور في 2020"…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …"
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Serotonin modulates L2 neuron visually induced calcium transient kinetics.
منشور في 2020"…Light or dark stimuli (A, middle panel, white and black vertical bars respectively) were flashed at random every 5 s for 6 min. …"
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Macroscopic and histological assessment of colic tumor and inflammation in mice.
منشور في 2020الموضوعات: -
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
منشور في 2022"…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
منشور في 2022"…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"
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RhoA gene expression and activity are impacted with increased intracellular 5HT.
منشور في 2020"…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …"
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GSK343 decreased neuroblastoma viability, proliferation, and motility.
منشور في 2021"…<p>(A) SK-N-AS, SK-N-BE(2), SH-EP and WAC(2) cells (1.5 × 10<sup>3</sup> cells) were treated with increasing concentrations of GSK343 (0, 5, 15, 25 μM) for 24 hours and viability was measured using alamarBlue<sup>®</sup> assay. …"
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Design, Synthesis, and Biological Evaluation of New Peripheral 5HT<sub>2A</sub> Antagonists for Nonalcoholic Fatty Liver Disease
منشور في 2020"…Here, structural modifications of pimavanserin (CNS drug), a 5HT<sub>2A</sub> antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT<sub>2A</sub> antagonists. …"
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